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Clin Med I Exam 2
Cardiac
220
Other
Graduate
09/30/2012

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Term
How BP is
Definition
the force against arterial walls
Term
BP is the product of
Definition
CO x PVR
Term
treatment of BP works to reduce these key factors
Definition
CO(SVxHR) and PVR
Term
Normotensive reading
Definition
<120/<70
Term
Primary HTN reading Stage I
Definition
140-159/90-99
Term
Primary HTN reading Stage II
Definition
>160/>100
Term
Secondary HTN characteristics
Definition
Abrupt Onset
Asymptomatic
End Organ Damage
Term
Malignant HTN Characteristics
Definition
1% of all patients with HTN
Can be fatal
Symptoms include:
drowsiness, confusion, HA, nausea,
loss of vision, respiratory distress
Term
HTN in pregnancy with preeclampsia
Definition
protein in urine, HAs, edema
toxemia
10% of Pregnancies
3rd tri
severe, sudden onset
low birth weight
fetus- eye or brain damage
mother- kidney damage, convulsion and coma
Term
HTN in pregnancy without preeclampsia
Definition
before 16-20 weeks
older women
medication for treatment
can continue after pregnancy
Term
Symptoms of HTN
Definition
"silent killer"
HA
Dizziness
Visual changes
Term
Clinical Clues of HTN
Definition
Family history

Hypokalemia

Truncal obesity; moon face; hirsutism; bruising

Morbid obesity; nocturnal snoring

Renovascular Hypertension-Early onset; atherosclerosis; worsening renal function with ACE/ARB

Pheochromocytoma- Pallor; head pain; perspiration; paroxysmal hypertension/postural hypotension

Polycystic Kidney- Bilateral flank masses

Coarctation- Diminished pulses; rib notching; UE pulses greater than LE pulses (

Renal Parenchymal disease- Flank pain; dysuria; hematuria; anemia; volume overload; history RD


Drug Induced-NSAID’s; drug abuse; steroids; ETOH; contraceptives; decongestants;

Thyrotoxicosis-Excess thyroid hormone, tachycardia, goiter
Term
Causes of Primary HTN
Definition
Unknown, but probably genetic or lifestyle causes.
Term
Cause of secondary hypertension
Definition
Uncontrolled essential hypertension resulting in end organ damage
Term
hypertensive risk factors
Definition
Family history of hypertension
Tobacco
Alcohol
Dyslipidemia
Diabetes Mellitus
CAD
CVD
CHF
PVD
Renal Disease
Term
Roles of Race and Ethnicity in hypertension
Definition
Increases with age
Age 65 > majority whites hypertensive
African Americans Develop Hypertension much earlier, most by age 55
Highest prevalence rates are in elderly African American women > 75%
After age 75
Term
Lifestyle factors of hypertension
Definition
Obesity
Dietary
Tobacco
Alcohol
Salt and Potassium intake
Physical Inactivity
STRESS
Term
"Stroke Belt"
Definition
states with stroke mortality more than 10% above the national mean.
10 of the 11 states in the stroke belt are in the Southeastern United States
Term
risks of untreated hypertension
Definition
Stroke
Cardiomegally
Cardiomyopathy
Heart Attack
Congestive heart failure
Cardiac Arrhythmia
Diabetes
Kidney Disease/Failure
Visual Changes
Sexual dysfunction
Term
Initial work up for HTN
Definition
History
Physical Examination – BP, Fundoscopic, Cardiac, Pulses, Abdomen
Testing – urinalysis, creatnine, potassium, glucose, uric acid, calcium, lipid profile, EKG.
Treatment choice algorithm (Risk group A-C)
4 major
Term
The 4 major Objectives of the initial work-up
Definition
Define severity of hypertension and identify target organ disease (if any)
Determine other risk factors for cardiovascular disease
Look for clues of secondary causes of hypertension
Confirm that hypertension is sustained
Term
Number of BP reading to be done before diagnosis of HTN
Definition
at least 2
UNLESS Pressure > 180/112 --> Diagnosis made-->start treatment
Term
Cardiovascular risk ____ with increasing pressures
Definition
rises
Term
Systolic pressure is a ____(better;worse) predictor of events than diastolic
Definition
better
UNLESS < 50 yrs of age, then Diastolic is better
Term
_________ represents decreased arterial compliance and is an even better indicator of cardiovascular risk.
Definition
Pulse pressure
Term
antihypertensive plan
Definition
Pharmacologic therapy
HTN results from an altered hemodynamic relationship between cardiac output and total peripheral resistance and either or both may be elevated.
Antihypertensive agents can be characterized by their ability to lower cardiac output or total peripheral resistance.
Pick an agent based on the underlying hemodynamic abnormality
Term
major pharmacologic categories or classes
Definition
Diuretics
Beta-Blockers
Central Acting Adrenergic Agents
Vasodialators
ACE Inhibitors
Alpha blockers
ARBs
CCBs
Term
treatment of resistant hypertension
Definition
Add new drugs
Consider possible non-compliance
Look for secondary causes
Rule our renal artery stenosis (No ACE if present)
Refer to hypertension specialist/clinic
Term
Non-Pharmacologic therapy
Definition
Lifestyle modification
Term
Drug treatment of hypertensive emergencies
Definition
Nitroprusside
Nitroglycerin
Labetalol
Esmolol
Enalaprit
Term
Drugs shown to reduce morbidity and mortality
Definition
diuretics, beta blockers and ace inhibitors
Term
Beta blockers can induce ______in patients with chronic lung disease
Definition
bronchospasm
Term
____________ may worsen renal function, especially so if RA stenosis is present
Definition
ACE inhibitors
Term
Thiazide diuretics are ineffective when serum creatnine > ________
Definition
2.5mg/dl.
Term
Spirinolactone may induce ______________
Definition
hyperkalemia
Term
Alpha blockers can induce _____hypotension in the elderly
Definition
postural
Term
ACE Inhibitors and ARB’s are contraindicated in ___________
Definition
pregnancy
Term
Abrupt cessation of Clonidine may lead to ________hypertension
Definition
rebound
Term
Beta Blockers CAN _____triglyceride levels and _____HDL cholesterol levels
Definition
raise;lower
Term
Metabolic Syndrome clues
Definition
Obesity
Hypertension
Hyperglycemia
Hypertriglyceridemia
Low HDL
Term
Sinus Arrhythmia _______ HR with inspiration
Definition
increases
Term
Sinus Arrhythmia is common in these populations
Definition
young and elderly
Term
Sinus Arrhythmia types
Definition
1. Paroxysmal Supraventricular Tachycardia (PSVT)
2. Atrial Fibrillation
3. Atrial Flutter
Term
Sinus Arrythmias are due to
Definition
Reflex changes in vagal tone
Term
Sinus Bradycardia due to
Definition
increase in vagal tone
Term
Sinus bradycardia has HR of
Definition
<60bpm
Term
Sinus Bradycardia is common among
Definition
healthy persons/athletes
Term
In Sinus Bradycardia HR _______ with exercise or atropine
Definition
increases
Term
Sinus Tachycardia
Definition
HR > 100 bpm
Term
Causes of Sinus Tachycardia
Definition
Fever, exercise, pain, anemia, shock, hyperthyroid etc
Term
Onset and termincation of Sinus Tachycardia
Definition
gradual
Term
If Sinus Tachycardia is higher than 160bpm
Definition
think other atrial arrhythmias
Term
Premature Atrial Beats (PAC’s)have an abnormal _-wave
Definition
P
Term
________in HR usually makes PACs disappear
Definition
Increase
Term
PACs
Definition
Firing of atrial ectopic focus
Term
paroxysmal supraventricular tachycardia types
Definition
i. AVNRT
ii. AVRT
Term
Which type of paroxysmal supraventricular tachycardia is more commone
Definition
AVNRT
Term
AVNRT
Definition
- re-enters AV node;circular re-entry
Term
AVRT
Definition
re-entry pattern somewhere other than the AV node-->more dangerous because there is no refractory period
Term
Signs and Symptoms of paroxysmal supraventricular tachycardia
Definition
palpitations/CP/SOB
EKG-HR usually 160-220 bpm and regular
Term
Treatments of paroxysmal supraventricular tachycardia
Definition
i. Mechanical measures: Valsalva, head b/t knees, cold water (baroreceptors reset), cough, carotid sinus massage (baroreceptors reset)
ii. Drugs: adenosine, Ca2+ blockers, B-blockers
iii. Cardioversion
iv. Ablation
Term
WPW (supraventricular tachycardia) has an additional wave called a
Definition
delta wave- occurs at beginning of QRS wave
Term
Treatment of supraventricular tachycardias
Definition
catheter ablation or drugs
Term
atrial fibrillation
Definition
most common chronic arrythmia
Term
causes of atrial fibrillation
Definition
Valvular dz., CHF, HTN, hyperthyroid, CAD, “holiday heart”, pulm. dz., chest trauma, surgery
Term
Signs and Symptoms of atrial fibrillation
Definition
palpitations, fatigue, irregularly irregular rhythm on exam
EKG-ALWAYS irregularly irregular rhythm;no P-waves
Term
treatment of hemodynamically stable atrial fibrillation
Definition
AV blocking agents or cardioversion (48 hr rule) - risk for embolism goes up because it will push it out. Put them on blood thinners and control heart rate. Fix it later
Term
treatment of hemodynamically unstable atrial fibrillation
Definition
cardioversion
Term
Long-term Management of A. fib
Definition
Ventricular Rate control (drugs) & anticoagulation (Coumadin)

vs.

Restoring sinus rhythm (drugs/cardioversion) & antiarrhythmic drugs

Paroxysmal A. fib-needs anticoagulation
Term
Atrial Flutter Rythym
Definition
REGULAR, really fast- conduction 4:1 or 3:1 P to QRS waves
Term
Atrial Flutter EKG
Definition
250-350 bpm-regular rhythm-variable conduction
Sawtooth pattern
Term
Atrial Flutter Treatment
Definition
vii. Rate control
viii. Anticoagulation
Term
Ventricular Premature Beats
Definition
Isolated beats from ventricular tissue-benign in healthy hearts

GOES AWAY WITH EXERCISE
Term
Bigeminy PVCs
Definition
Every other regular beat is a PVC
Term
Trigeminy PVC
Definition
every 3rd beat is a PVC
Term
Ventricular Tachycardia
Definition
3 or more consecutive PVC’s-usu. 160-240 bpm
Term
Ventricular Tachycardia-->patients with
Definition
Acute MI
Cardiomyopathy
Myocarditis
Term
Nonsustained V. tach
Definition
less than 30 sec. and terminating spontaneously
Term
Treatment of Nonsustained V-tach
Definition
-treat with drugs (B-blockers)
Term
treatment of sustained V. tach with LV dysfunction (CHF)
Definition
need defibrillator
Term
treatment of sustained V. tach with normal LV function
Definition
can try medical mgmt (B-blockers, amiodarone)
Term
What are the causes of V-fib
Definition
LVH, CHF, HCM, A.S., PPH, congenital heart dz, Brugada syndrome
Term
When V-fib often occurs
Definition
early am hours
Term
long QT syndrome
Definition
rare inborn heart condition in which delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes
Term
torsade de pointes
Definition
TDP, a form of irregular heartbeat that originates from the ventricles
Term
long QT syndrome can lead to
Definition
palpitations, fainting and sudden death due to ventricular fibrillation. Episodes may be provoked by various stimuli, depending on the subtype of the condition
Term
sick sinus syndrome
Definition
Fibrosis of conduction system
Term
Sinus sick syndrome is most common in what population
Definition
the elderly
Term
sick sinus syndrome symptoms
Definition
syncope, dizziness, palpitations
Term
sick sinus syndrome treatment
Definition
pacemaker
Term
Accelerated idioventricular rhythm
Definition
rhythm of ectopic ventricular origin, faster than the normal rate of the His-Purkinje system but slower than 100 beats per minute, without retrograde conduction to the atria
Term
1st degree AV block
Definition
PR interval > 0.21 sec ( a little prolonged) You watch it to see if it progresses further. No real treatment.
Term
2nd degree AV block
Definition
Mobitz Type I (Wenckebach)-PR interval progressively lengthens then drops a beat (drugs, ischemia, fibrosis etc.) P wave gets longer and longer and longer then drops.

Mobitz Type II-intermittently drop beats w/o PR interval lengthening (usu. organic dz) drop beat = no QRS, its gone, then picks back up.

Usually progress to 3rd degree, watch closely. Usually get pacemakers before it gets to 3rd degree.
Term
3rd degree AV block
Definition
complete dissociation b/t atria and ventricles-slow ventricular rate at around 45 bpm
i. Atria does its own thing, ventricle does its own thing. Won’t really see a P-wave because QRS overrides it.
ii. Need-pacemake
iii. AV (Heart) Block
Term
Intraventricular conduction
Definition
a delay in conduction of a ventricular impulse within the ventricles that does not correspond to either a right bundle branch block or a left bundle branch block.
Term
AV dissociation
Definition
control of the atria by one pacemaker and of the ventricles by another, independent pacemaker
Term
VASODEPRESSOR
Definition
(vasovagal, neurocardiogenic)-”faint”-common in young women in response to stress, pain, claustrophobia
Term
VASODEPRESSOR Treatment
Definition
lying down, removing offending stimulus, fluids, supportive care
Term
VASODEPRESSOR symptoms
Definition
Nausea, diaphoresis, tachycardia prior to fainting
Term
ORTHOSTATIC (POSTURAL) HYPOTENSION
Definition
elderly, DM, autonomic neuropathy, drugs (vasodilators, diuretics, B-blockers etc.), volume depletion
Term
ORTHOSTATIC (POSTURAL) HYPOTENSION signs
Definition
>20 mm Hg decline in BP upon standing
Term
ORTHOSTATIC (POSTURAL) HYPOTENSION treatment
Definition
gait training/stability, remove offending agents, volume repletion
Term
CARDIOGENIC SYNCOPE
Definition
usu. no prodrome so injury is common
Mechanical: A.S., pulm. stenosis, HCM, congenital heart dz
Term
CARDIOGENIC SYNCOPE Signs
Definition
Arrhythmic: sick sinus, AV block, SVT, V. tach
Term
CARDIOGENIC SYNCOPE Treatment
Definition
fix/treat underlying problem
Term
Questions to ask about Arrythmias
Definition
a.Slow or fast? Rate helps diagnose
b.If fast, how fast?
c.Regular or irregular?
d.Narrow (atrial) or wide (ventricular) complex?
e.Symptomatic?
Term
Signs of Cardiac disease
Definition
1. Change in alertness
2. Gripping chest or throat
3. Palor or Cyanosis
4. Labored breathing
5. Sweating
6. Apnea/No pulse
Term
cardiac disease Symptoms
Definition
1. Chest pain
2. Shortness of breath
3. Weakness and feeling lightheaded
4. Nausea and vomiting
5. Pain, numbness, and swelling in the feet and ankles, abdomen
6. Pale skin with or without sweating
7. Wet cough
8. Indigestion
9. Anxiety and restlessness
10. Backache
11. Difficulty feeding and poor weight gain in infants
12. Erectile dysfunction
13. Fatigue
14. Activity intolerance
15. PND
16. Orthopnea
17. Change in level of consciousness or alertness
18. Fatigue or activity intolerance
19. Extreme sweating and clammy, pale skin
Term
Ventricle dilation and hypertrophy
Definition
i. Reduced pumping efficiency
ii. Heart Failure
iii. Development of arrhythmias, blood clots, reduced exercise capacity, shortness of breath, fainting, fatigue
Term
Cardiomyopathy Genetic
Definition
Hypertrophic Cardiomyopathy
Term
Cardiomyopathy Acquired (causes)
Definition
Inflammatory, peripartum, Viral Infections, Sarcoidosis
Term
Cardiomyopathy toxin (causes)
Definition
Drugs, Alcohol, Heavy Metals, Chemotherapeutic agents
Term
Cardiomyopathy Endocrine Disorders (causes)
Definition
Diabetes, Thyroid Disease
Term
Cardiomyopathy Autoimmune Disorders (causes)
Definition
Lupus, RA, Scleroderma
Term
Cardiomyopathy Nutritional Deficiencies (causes)
Definition
Beri-beri, Scurvy
Term
Types of Cardiomyopathy
Definition
Genetic
Acquired
Toxins
Endocrine Disorders
Autoimmune Disorders
Nutritional Deficiencies
Term
Pericardial Disease
Definition
puts pressure on the heart, causing poor heart function. If left untreated, pericardial effusion can cause heart failure or death

Pericardial effusion may be related to inflammation of the pericardium that's caused by disease or injury

pericardial effusion can also occur without inflammation.

Pericardial effusion can be caused by the accumulation of blood after a surgical procedure or injury
Term
CHF
Definition
Heart loses its ability to blood to body
Term
CHF symptoms
Definition
1. Shortness of breath
2. Chest pain
3. Syncope
4. Reduced exercise tolerance
5. Orthopnea/Paroxysmal Nocturnal Dyspnea
6. Extremity or Abdominal edema
7. Blood clots
Term
Dyspnea is associated with what diseases
Definition
Orthopnea, Paroxysmal nocturnal dyspnea, decreased LV function causing increased LA pressure transmitted through the pulmonary veins leading to venous congestion
Term
Chest Pain is associated with what conditions
Definition
Pericarditis, Aortic dissection, Pulmonary Emboli, MI
Term
Palpitations are associated with what conditions
Definition
cardiac arrhythmias
Term
Syncope is associated with what conditions
Definition
Acute MI, Valvular disease, Hypertrophic obstructive cardiomyopathy, Arrhythmias, Reflex vasodilatation or bradycardia, Acute pulmonary embolism, Hypovolemia
Term
Edema is associated with what conditions
Definition
Increase LV pressure leads to pulmonary edema
increased RV pressure leads to peripheral edema
Term
Cyanosis is associated with what conditions
Definition
: left heart shunting as caused by a structural abnormality (ASD or VSD), pulmonary parenchymal disease or vascular disease (COPD, PE, pulmonary AV fistula), vasoconstriction due to decreased cardiac output
Term
Fatigue is associated with what conditions
Definition
nonspecific symptom of cardiac disease; by poor cardiac output or even medical therapy
Term
elements of a general screening cardiovascular physical examination
Definition
a. Fundoscopic
b. Jugular Venous pressures
c. Carotid Auscultate
d. Arterial Pressure
e. Precordium
f. Auscultation of the chest
g. Abdominal Exam
h. Pulses
i. Diagnostic testing
Term
CV disease diagnostic tests
Definition
Blood Work
CT
MUGA
Nuclear Cardiology
Cardiac Cath
Echocardiogram
Stress Tests
EKG
MRI
U/S
Term
risk factors for coronary artery disease
Definition
a. Diabetes (DM)
b. Hypertension (HTN)
c. Hyperlipidemia
d. Male sex, + FH of CAD, age, obesity, smoking, sedentary lifestyle, poor diet
e. CAD is a disease of risk factors
f. Metabolic Syndrome
g. C-Reactive Protein (CRP)
h. Myocardial hybernation
i. Angina
Term
chronic stable angina pectoris symptoms
Definition
• Circumstances-consistently reproducible, relieved with NTG/rest
• Characteristics-typical pain pattern
• Location/Radiation-often L shoulder/upper arm
Term
chronic stable angina pectoris signs
Definition
HTN, murmur, signs of other diseases
Term
chronic stable angina pectoris EKG at rest
Definition
normal
Term
chronic stable angina pectoris EKG on exertion
Definition
ST-segment depression, T wave flattening/inversion
Term
What are differential diagnoses for Chest Pain
Definition
GERD
Pneumonia
PE
Pneumothorax
Costochondritis
Pericarditis
Aortic Dissection
Term
Treatment of Stable Angina
Definition
1. Nitrates (vasodilators)
2. Beta-blockers-decrease mortality
3. Calcium channel blockers-anti-anginal properties
4. Anti-platelet agents (ASA, Plavix)
5. Revascularization-stenting vs. CABG
Term
acute coronary syndrome
Definition
a classification encompassing clinical presentations ranging from unstable angina through non, sometimes also including Q wave infarction.
Term
Coronary vasospasm
Definition
normal or diseased arteries-triggered by cold, emotional stress, vasoconstricting meds (Cocaine)
Term
Prinzmetal angina (syndrome “X”)
Definition
women < 50 yo without usual risk factors, often early am sx. which awaken pt. from sleep, can have arrhythmias and conduction defects,
Term
Prinzmetal angina EKG
Definition
EKG = ST segment elevation
Term
Prinzmetal angina treatment
Definition
treat with nitrates and Ca2+ channel blockers
Term
NSTEMI EKG
Definition
ST-segment depression, T wave flattening/ inversion
Term
NSTEMI treatment
Definition
• Anticoagulation/anti-platelet therapy-ASA, Plavix, LMWH etc.
• Nitrates-vasodilators
• Beta-blockers-decrease mortality-decrease sympathetic activity
1. Control sympathetic surge (Epi/NE)
2. Post op arrhythmia risk
• Statins-anti-inflammatory properties
• Coronary angiography
Term
NSTEMI labs
Definition
• CK-MB-serial enzymes (positive enzymes) MB fraction
1. Serial enzymes-draw more than once because there is a lag time between onset of symptoms every 6-8 hrs for 3 sets (24 hrs)
• Troponin-very sensitive and specific (+ for 5-7 days)-may not be elevated early-careful with renal insufficiency
1. Can be elevated superficially in renal insuffiency
Term
STEMI Symptoms
Definition
o pain at rest,
o often in early am-sweaty,
o apprehensive,
o N/V,
o dyspnea,
o sudden death and
o ventricular arrhythmias more common-can have painless infarction (DM, women, elderly)
Term
STEMI Signs
Definition
anxious, diaphoretic, resp. distress, CHF
Term
STEMI Labs
Definition
o CK-MB
o Troponin
Term
STEMI EKG
Definition
ST-segment elevation which can progress to Q waves (Q-wave vs. non-Q-wave MI)
Term
STEMI Treatment
Definition
o Anti-platelet therapy
o Analgesia-morphine (also a vasodilator), morphine is helpful in acute MI
o Beta-blockers-careful with bradycardia or shock, DECREASE HR
o Nitrates
o ACE inhibitors-decrease remodeling, really good for post MI, in response to Hypoxia
o Coronary angiography, thrombolytics
Term
complications of acute myocardial infarction
Definition
o Postinfarction ischemia
• Myocardial Dysfunction
• RV infarction
• Mechanical defects-papillary muscle or IV septum rupture
• Myocardial rupture-LV free wall
• LV aneurysm
• Pericarditis-Dressler syndrome
• Mural thrombus-large anterior infarcts-arterial emboli
Term
post-infarction management
Definition
 Statins
 Beta-blockers-reduce sudden death
 Antiplatelet therapy (ASA, Plavix, warfarin, aspirin)
 ACE inhibitors/ARB’s-prevents cardiac remodeling esp. with LV dysfunction/CHF
 Cardiac rehab/exercise programs
Term
Signs and Symptoms of Right sided HF
Definition
1. Marked JVD
2. Clear chest
3. Hypotension
4. Marked peripheral edema
5. Ascites, hepatomegaly
6. Poor exercise tolerance
Term
Treatment of Right Sided HF
Definition
1. Often will be on Lasix, Digoxin,
2. Have chronic pump failure
Term
Signs and Symptoms of left-sided HF
Definition
Severe apprehension, agitation, confusion
Pulmonary congestion
Jugular Venous Distention
Level of Conciousness
Chest Pain
Diaphoresis
Cyanosis
Term
Signs of CHF
Definition
Severe apprehension, agitation, confusion
Pulmonary congestion
Jugular Venous Distention
Term
CHF CXR
Definition
i. Kerley’s lines : A and B fluid infiltrating between lobes
ii. Pulmonary Edema
iii. Cephalization
iv. Pleural Effusions (bilateral)
v. Cardiomegaly – bigger than half chest cavity
Term
CHF EKG
Definition
i. Can have weird heart rhythms
ii. Left atrial enlargement
iii. Arrhythmias
iv. Hypertrophy (left or right)
v. Types of rhythms
Term
CHF Clinical Data
Definition
i. Heart Sounds noted with CHF (sometimes)
ii. Systolic Murmurs
1. Mitral Regurg
2. Aortic Stenosis
iii. Diastolic Murmurs
1. Mitral Stenosis
2. Aortic Insufficiency
iv. S3: Rapid filling of a diseased ventricle, ken-tuc-kee
v. S4: valves flapping ten-ess-ee
Term
CHF Labs
Definition
i. Chemistry
1. Renal Function: Be Wary
ii. BNP > 5000 is CHF (if neg BNP, not CHF)
1. Used in ER departments the world over
2. Good negative correlation
3. Need baseline for positivity
4. Pulmonary versus cardiac dyspnea
Term
CHF Drug Therapies
Definition
ii. Vasodilators—ACE inhibitors
iii. Diuretic agents
iv. Inotropic agents
v. CCB
vi. BB
Term
HF Signs and Symptoms
Definition
1. Pulmonary congestion (left heart failure)
dyspnea (rest, exertional, nocturnal), orthopnea
2. Systemic congestion (right heart failure)
edema, nausea, abdominal pain, nocturia
3. Low cardiac output
4. Hypotension, tachycardia, tachypnea
5. Fatigue and weakness
Term
HF Diagnosis
Definition
1. CXR (enlarged heart, CHF)
2. Electrocardiogram (tachycardia, A-V block, LBBB, NSSTT changes, PVC’s)
3. 24-hour Holter monitor
a. if lightheadedness, palpitation, syncope
4. Echocardiogram (left ventricular dilation, global hypokinesis, low EF)
5. Myocardial biopsy, rare
6. Cardiac catheterization (R/O CAD)
Term
Pulmonary Edema Symptoms
Definition
1. shortness of breath upon exertion
2. sudden respiratory distress after sleep
3. difficulty breathing, except when sitting upright
4. coughing
Term
Pulmonary Edema Diagnosis
Definition
1. Rapid pulse, rapid breathing, abnormal breath and heart sounds, and enlarged neck veins.
2. Chest x ray is often used to confirm the diagnosis.
3. Arterial blood gas testing may be done.
4. Sometimes pulmonary artery catheterization is performed to confirm that the patient has pulmonary edema and not a disease with similar symptoms
Term
Pulmonary Edema Treatment
Definition
1. Placing the patient in a sitting position,
2. Oxygen
3. Assisted or mechanical ventilation (in some cases)
4. Drug therapy
5. The goal of treatment is to reduce the amount of fluid in the lungs, improve gas exchange and heart function, and, where possible, to correct the underlying disease.
Term
NYHA Class I
Definition
Cardiac disease, but no symptoms and no limitation in ordinary physical activity, e.g. shortness of breath when walking, climbing stairs etc
Term
NYHA Class II
Definition
Mild symptoms (mild shortness of breath and/or angina) and slight limitation during ordinary activity.
Term
NYHA Class III
Definition
Marked limitation in activity due to symptoms, even during less-than-ordinary activity, e.g. walking short distances (20–100 m).Comfortable only at rest.
Term
NYHA Class IV
Definition
Severe limitations. Experiences symptoms even while at rest. Mostly bedbound patients.
Term
AHA/ACC Heart Failure Stage A
Definition
People at high risk for developing heart failure but who do not have heart failure or damage to the heart
Term
AHA/ACC Heart Failure Stage B
Definition
People with damage to the heart but who have never had symptoms of heart failure; for example, those who have had heart attack
Term
AHA/ACC Heart Failure Stage C
Definition
People with heart failure symptoms caused by damage to the heart, including shortness of breath, tiredness, inability to exercise
Term
AHA/ACC Heart Failure Stage D
Definition
People who have advanced heart failure and severe symptoms difficult to manage with standard treatment
Term
Dilated Cardiomyopathy
Definition
Ventricular dilation, hypokinetic left ventricle, and systolic dysfunction
Term
Dialated cardiomyopathy
Definition
Term
Most common of the cardiomyopathies
Definition
Dilated cardiomyopathy
Term
Hypertrophic cardiomyopathy
Definition
i. Genetic disease characterized by hypertrophy of the left ventricle with marked variable clinical manifestations morphologic and hemodynamic abnormalities
Term
Hypertrophic cardiomyopathy without Obstruction
Definition
Exessive thickening of the muscle
Hypertrophy is usually greatest in the septum.
left ventricle is almost always affected
Term
Hypertrophic cardiomyopathy with Obstruction
Definition
Asymmetric septal hypertrophy with obstruction to the outflow of blood from the heart may occur
Term
Restrictive Cardiomyopathy
Definition
Abnormal diastolic function
Rigid ventricular wall with impaired ventricular filling
Bear some functional resemblance to constrictive pericarditis
Importance lies in its differentiation from operable constrictive pericarditis
Term
Restricive Cardiomyopathy Classifications
Definition
Idiopathic
Myocardial
Noninfiltrative
Endomyocardial
Term
Restricive Cardiomyopathy Signs and Symptoms
Definition
Symptoms of right and left heart failure
Term
Dialated Cardiomyopathy Diagnosis
Definition
1. CXR (enlarged heart, CHF)
2. Electrocardiogram (tachycardia, A-V block, LBBB, NSSTT changes, PVC’s)
3. 24-hour Holter monitor
a. if lightheadedness, palpitation, syncope
4. Echocardiogram (left ventricular dilation, global hypokinesis, low EF(below 35%))
5. Myocardial biopsy, rare
6. Cardiac catheterization (R/O CAD)
Term
Dialated Cardiomyopathy Treatment
Definition
1. Limit activity based on functional status
2. Salt restriction
3. Fluid restriction
4. Initiate medical therapy
5. Cardiac transplantation
6. Left Ventricular Reduction Procedures
Term
Hypertrophic Cardiomyopathy Diagnosis
Definition
1. Echocardiogram
2. EKG
Term
Hypertrophic Cardiomyopathy Treatment
Definition
1. Beta-adrenergic blockers (atenolol, toprol, sotalol, tenormin etc)
2. Calcium channel blockers (norvasc, cardizem, etc)
3. Anti-arrhythmics – Amiodarone, norpace
4. Pacemakers (ICD)
5. Myomectomy (resection of septum)
6. Alcohol septal ablation (controlled MI through septal perforator perfusing basal septum) -->wall thinning-->decreases in LVOTO
7. Transplantation
Term
Restrictive Cardiomyopathy Diagnosis
Definition
Symptoms of right and left heart failure
Jugular Venous Pulse
Echo-Doppler
Abnormal mitral inflow pattern
Prominent E wave (rapid diastolic
filling)
Reduced deceleration time (increased LA
pressure)
Term
Restrictive Cardiomyopathy Treatment
Definition
i. No satisfactory medical therapy
ii. Drug therapy must be used with caution
1. Diuretics for extremely high filling pressures
2. Vasodilators may decrease filling pressure
3. (?) Calcium channel blockers to improve diastolic compliance
4. Digitalis and other inotropic agents are not indicated
Term
cor pulmonale symptoms
Definition
a. Retrosternal Chest Pain
b. Cough
c. Dyspnea
d. Fatigue
e. Sputum production
Term
cor pulmonale signs
Definition
1. Tachycardia
2. Cyanosis
3. Finger Clubbing
4. Accentuated right ventricle precordial thrust
5. Along left sternal border
6. Accentuated and Split pulmonic heart sound (P2)
7. Right sided S4 Heart Sound
8. Right Sided Heart Failure signs
9. Kussmaul's Sign
10. Distention of jugular neck veins on inspiration
11. Pulsus Paradoxus
12. Exaggerated fall in Blood Pressure on inspiration
13. Jugular Vein Distention
14. Hepatomegaly with Ascites
15. Pedal edema
Term
cor pulmonale findings
Definition
a. Mitral Stenosis
b. Left to right cardiac shunts
Term
cor pulmonale CXR
Definition
• Enlarged pulmonary artery
• Dilated right ventricle
• Primary Pulmonary Hypertension signs
• Tapering of pulmonary artery branches
Term
cor pulmonale V/Q
Definition
• Evaluate suspected recurrent Pulmonary Embolism
Term
Idiopathic Pulmonary Hypertension
Definition
is a progressive condition that affects the heart and lungs.
Term
Idiopathic Pulmonary Hypertension Symptoms
Definition
ii. Dyspnea (60% of patients)
iii. Weakness (19%)
iv. Recurrent syncope (13%)
v. Women are more likely to be symptomatic than men.
Term
Epicarditis Pain
Definition
Often described as more of a sharp, stabbing pain in, often lasts for hours, positional
Term
Aortic dissection pain
Definition
Knifelike, excruciating chest pain more common in– tearing pain
Term
Pulmonary Embolism Pain
Definition
sharp, pleuritic chest pain, worse with inspiration, cough
Term
Costocondritis Pain
Definition
sharp, worse with inspiration, cough, movement(rule out others)
Term
Esophagitis/gastritis pain
Definition
Dull, retrostrenal, may be positionalor associated with eating
Term
Herpes Zoster Pain
Definition
Pain associated with rash
Term
Dyspnea
Definition
an uncomfortable, heightened awareness of breathing frequently experienced during exertion, although can be experienced at rest in severe cardiac disease
Term
Orthopnea
Definition
inability to breath while supine– need an extra pillow or two
Term
Paroxysmal nocturnal dyspnea
Definition
premature reawakening due to dyspnea
Term
Dyspnea causes
Definition
decreased LV function causing increased LA pressure transmitted through the pulmonary veins leading to venous congestion
Term
what Venous congestion lead to
Definition
exudation of the fluid into the alveolar space leading to decreased gas exchange
Term
In cardiac patients dyspnea can be an ______ __________
Definition
anginal equivalent
Term
what is an anginal equivalent
Definition
a symptom other than typical anginal type chest pain, with the same cause
Term
Palpitations
Definition
the subjective sensation of the heart beating
Term
Syncope
Definition
is the transient loss of consciousness resulting from inadequate cerebral blood flow
Term
cardiac disease edema is the result of ______________________
Definition
increased venous pressure
Term
_______LV pressure leads to pulmonary edema and ________ RV pressure leads to peripheral edema
Definition
Increase; increased
Term
cyanosis
Definition
the unusual bluish discoloration of the skin
Term
Cyanosis is a reflection of
Definition
decreased arterial oxygenation (lower than 85%)
Term
Central cyanosis often results from
Definition
from right to left heart shunting as caused by a structural abnormality (ASD or VSD)
pulmonary parenchymal disease or vascular disease (COPD, PE, pulmonary AV fistula)
Term
Peripheral cyanosis may be a result of
Definition
systemic vasoconstriction due to decreased cardiac output
Term
Localized peripheral cyanosis may be a result of
Definition
venous or arterial occlusive or vasospastic disease (thrombotic, embolic, Raynauds)
Term
Fatigue may be caused by
Definition
poor cardiac output or even medical therapy
Term
Fatigue may be the only symptom of cardiac disease in
Definition
in atypical populations, dementia, stoic individuals
Term
Ventricle dilation and hypertrophy can cause
Definition
Reduced pumping efficiency
Heart Failure
Development of arrhythmias, blood clots, reduced exercise capacity, shortness of breath, fainting, fatigue
Term
Causes of CHF
Definition
loss of heart muscle contractility,
valvular dysfunction,
fluid overload,
hyperdynamic state
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