| Term 
 | Definition 
 
        | Superficial infection that causes honey-colored crusts.  Only epidermis is involved, so no scarring once it heals.  Does not causes "sick" patient.  Can be caused by streptococcus or other bacteria.  Can involve the hair follicle - which makes crust more difficult to remove. |  | 
        |  | 
        
        | Term 
 
        | How do you treat impetigo?  Notes |  | Definition 
 
        | If small spot, use topical (bacitracin).  If large or if topical won't be used, use systemic oral abx. |  | 
        |  | 
        
        | Term 
 
        | Describe cellulitis.  Notes |  | Definition 
 
        | Skin infection that is deeper than impetigo.  It is not an abscess; it is firm throughout.  Cellulitis is not terribly demarcated.  Signs of inflammation. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Ecythema is like an impetigo infection that has gone deeper and now involves the dermis.  This can cause scarring after healing.  Impetigo may be the precursor. |  | 
        |  | 
        
        | Term 
 
        | Describe lymphangitis.  Notes |  | Definition 
 
        | Inflammation of the lymph system proximal to a distal injury.  Sometimes there is a breach in the skin. |  | 
        |  | 
        
        | Term 
 
        | How do you treat cellulitis?  Notes |  | Definition 
 
        | Treat with antibiotics - penicillin.  If suspect possibility of staph can treat with macrolide or sulfa drugs. |  | 
        |  | 
        
        | Term 
 
        | How do you treat lymphangitis?  Notes |  | Definition 
 
        | Hot compresses make it feel better and resting the arm is good.  Treat with abx - inpatient if septic.  Follow up is key. |  | 
        |  | 
        
        | Term 
 
        | T/F - Notes Staph can cause lymphangitis.
 |  | Definition 
 
        | True - but Strep is a more common cause. |  | 
        |  | 
        
        | Term 
 
        | Describe folliculitis.  Notes |  | Definition 
 
        | Infection of the hair follicle.  Does not have the crusting that is seen with impetigo.  May have pustules.  Will not see white heads or black heads - cannot squeeze material from deeper. |  | 
        |  | 
        
        | Term 
 
        | How do you treat folliculitis?  Notes |  | Definition 
 
        | If small, may not need abx.  Antiseptic.  Do not shave while treating! |  | 
        |  | 
        
        | Term 
 
        | Describe a furuncle.  Notes |  | Definition 
 
        | Deep infection in which pus is coming out of a deeper abscess.  Has a core of inspissated pus (drying).  May scar. |  | 
        |  | 
        
        | Term 
 
        | How do you treat a furuncle during induration?  Notes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How do you treat a furuncle once it spontaneously breaks or is fluctuant and ready to be broken open?  Notes |  | Definition 
 
        | Break open - no anesthetic needed and won't work well because of acidic wound.  Remove the core. |  | 
        |  | 
        
        | Term 
 
        | Describe a carbuncle.  Notes |  | Definition 
 
        | A collection of furuncles.  These are typically found on the back of the legs or the back of the neck. |  | 
        |  | 
        
        | Term 
 
        | How do you treat a carbuncle?  Notes |  | Definition 
 
        | Prescribe a pain med, abx, and hot compresses.  Wait for furuncles to come to the surface.  Cut out a 1 cm square, break up the inside, pack and leave open. |  | 
        |  | 
        
        | Term 
 
        | Describe erysipelas.  Notes |  | Definition 
 
        | "Slapped face" rash.  Fever.  Firm.  Septic!!  Commonly on face, but can occur other places. |  | 
        |  | 
        
        | Term 
 
        | How do you treat erysipelas?  Notes |  | Definition 
 
        | Abx, may put on IV to get ahead of this. |  | 
        |  | 
        
        | Term 
 
        | What drugs should be used to treat pharyngitis and impetigo?  Notes |  | Definition 
 
        | Penicillin or erythromycin (macrolide) |  | 
        |  | 
        
        | Term 
 
        | What drugs should be used to treat cellulitis and erysipelas?  Notes |  | Definition 
 
        | Penicillin or dicloxacillin |  | 
        |  | 
        
        | Term 
 
        | What drugs do you use to treat necrotizing fasciitis or strep. toxic shock syndrome?  Notes |  | Definition 
 
        | Cindamycin (IV) and/or Penicillin |  | 
        |  | 
        
        | Term 
 
        | What are the 5 cardinal manifestations of rheumatic fever?  Notes |  | Definition 
 
        | 1. Carditis 2. Polyarthritis
 3. Erythema marginatum
 4. Subcutaneous nodules
 5. chorea
 |  | 
        |  | 
        
        | Term 
 
        | How many major manifestations of rheumatic fever must you have for diagnosis?  Notes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the 2 most common major manifestations of rheumatic fever?  Notes |  | Definition 
 
        | carditis and polyarthritis |  | 
        |  | 
        
        | Term 
 
        | If the patient presents with only 1 major manifestation of rheumatic fever, how many minor manifestations must the pt have? |  | Definition 
 
        | 1 major + 2 minor = diagnosis |  | 
        |  | 
        
        | Term 
 
        | What are the possible minor manifestations of rheumatic fever?  Notes |  | Definition 
 
        | arthralgia, fever, inc. acute-phase reactants, inc. erythrocyte sed rate, ince. C-reactive protein, prolonged PR interval |  | 
        |  | 
        
        | Term 
 
        | How do you prevent recurrent attacks of rheumatic fever?  Notes |  | Definition 
 
        | 1 of the following:  Penicillin, sulfadiazine, or erythromycin for allergic individuals |  | 
        |  | 
        
        | Term 
 
        | How long is secondary rheumatic fever prophylaxis continued?  Notes |  | Definition 
 
        | At least 10 years with carditis (maybe lifelong), and at least 5 years without carditis |  | 
        |  | 
        
        | Term 
 
        | Does long term secondary prophylaxis for rheumatic fever lead to drug resistance?  Notes |  | Definition 
 
        | There is no evidence that it does at this time. |  | 
        |  | 
        
        | Term 
 
        | Where is staphylococcus carried?  Notes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | T/F  - Notes Staphyloccocus in the nasopharynx can cause infection in the host or in others.
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | T/F  - Notes Staph usually causes an invasive, disseminated infection as opposed to a local infection.
 |  | Definition 
 
        | False - usually local but can invade |  | 
        |  | 
        
        | Term 
 
        | Why does Staph tend to complicate inflamed/traumatized tissue (ex. wounds)?  Notes |  | Definition 
 
        | surface receptors on Staph adhere to inflamed/traumatized tissue and thus complicate these areas |  | 
        |  | 
        
        | Term 
 
        | What types of infections are commonly caused by Staph?  Notes |  | Definition 
 
        | furuncle or skin abscess bullous impetigo
 surgical wound infection
 nosocomial bacteremia
 acute or R sided bacterial endocarditis
 hematogenous osteomyelitis
 septic arthritis
 pyomyositis
 renal carbuncle
 scalded skin syndrome
 toxic shock syndrome
 food-borne gastroenteritis
 botryomycosis
 paraspinous or epidural abscess
 |  | 
        |  | 
        
        | Term 
 
        | What types of infections are less commonly caused by Staph?  Notes |  | Definition 
 
        | cellulitis nosocomial pneumonia
 brain abscess
 empyema
 |  | 
        |  | 
        
        | Term 
 
        | What types of infections are rarely caused by Staph?  Notes |  | Definition 
 
        | CAP ascending UTI
 meningitis
 enterocolitis
 |  | 
        |  | 
        
        | Term 
 
        | What is Nikolsky's sign?  Notes |  | Definition 
 
        | Where the skin slips off - as in scalded skin syndrome |  | 
        |  | 
        
        | Term 
 
        | What are furuncles frequently mistaken for by patients?  Notes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What drug do we use to treat Staph and why?  Notes |  | Definition 
 
        | Bactrim DS - sulfa drug because Staph is getting more resistant to dicloxicillin and macrolides
 |  | 
        |  | 
        
        | Term 
 
        | When should you suspect a carrier state for Staph?  Notes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How do you treat the carrier state for Staph?  Notes |  | Definition 
 
        | Mupirocin ointment intranasally bid Rifampin plus dicloxacillin
 |  | 
        |  | 
        
        | Term 
 
        | When is the best time to treat osteomyelitis?  Notes |  | Definition 
 
        | the first time that it shows - be aggressive!  Don't let it come back! |  | 
        |  | 
        
        | Term 
 
        | What are the 3 types of osteomyelitis?  Notes |  | Definition 
 
        | Hematogenous, vertebral, and focal |  | 
        |  | 
        
        | Term 
 
        | What would the WBC count be in a patient with osteomyelitis?  Notes |  | Definition 
 
        | > 15,000 
 normal is about 5,000-10,000
 |  | 
        |  | 
        
        | Term 
 
        | What lab tests would you run for suspected osteomyelitis?  Notes |  | Definition 
 
        | CBC/WBC, Chem profile, sed rate, C-reactive protein, bone/blood C&S, bone biopsy, plain film x-ray |  | 
        |  | 
        
        | Term 
 
        | What are the 3 treatment options for osteomyelitis?  Notes |  | Definition 
 
        | 1. Medical 2. Medical/ surgical debridement/ stabilization
 3. Medical/ surgical amputation
 |  | 
        |  | 
        
        | Term 
 
        | Name 3 indications for surgery in an osteomyelitis case.  Notes |  | Definition 
 
        | 1. failure of medical treatment 2. soft tissue abscess
 3. joint sepsis/ instability
 |  | 
        |  | 
        
        | Term 
 
        | Name 4 factors that influence treatment and prognosis.  Notes |  | Definition 
 
        | 1. degree of necrosis 2. condition of host
 3. site and extent of involvement
 4. disabling effects
 |  | 
        |  | 
        
        | Term 
 
        | How do we classify osteomyelitis cases?  Notes |  | Definition 
 
        | Anatomic type 1-4 and physiologic class A-C 
 Anatomic type
 1. medullary
 2. superficial
 3. localized
 4. diffuse
 
 ?
 A. healthy
 B. immunocompromised
 C. treatment worse than disease
 |  | 
        |  | 
        
        | Term 
 
        | What is the most common cause of osteomyelitis?  Notes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | T/F  - Notes Staph. can cause GI infections.
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the definition of acute diarrhea?  Notes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the possible causes of acute diarrhea?  Notes |  | Definition 
 
        | infection, drug-related (abx, laxatives, etc), or IBD (inflammatory bowel disease such as Crohn's or UC) |  | 
        |  | 
        
        | Term 
 
        | What is the definition of chronic diarrhea?  Notes |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the possible causes of chronic diarrhea?  Notes |  | Definition 
 
        | drug-related, giardia, malabsorption, UC< tumors |  | 
        |  | 
        
        | Term 
 
        | What causes diarrhea pathophysiologically?  Notes |  | Definition 
 
        | decreased fluid absorption increased fluid secretion
 motor changes
 mucosal injury
 |  | 
        |  | 
        
        | Term 
 
        | What 10 things do you need to know when a patient complains of diarrhea?  Notes |  | Definition 
 
        | 1. Amount of water 2. blood
 3. pus
 4. time
 5. cramps
 6. travel
 7. food history
 8. contacts
 9. fluid intake
 10. temperature
 |  | 
        |  | 
        
        | Term 
 
        | When is Giardia especially likely?  Notes |  | Definition 
 
        | 1. hx of travel to mountainous areas of North America 2. travel to Russia (St. Petersburg)
 3. travel to developing tropical/semitropical world
 4. Contact with day care centers
 |  | 
        |  | 
        
        | Term 
 
        | What are the 5 key things to note during the physical exam of the patient with diarrhea?  Notes |  | Definition 
 
        | 1. hydration 2. overall appearance
 3. age
 4. vitals
 5. abdominal exam
 |  | 
        |  | 
        
        | Term 
 
        | What lab tests should be run on a patient presenting with diarrhea?  Notes |  | Definition 
 
        | Stool C&S, WBC, RBC, Ova and parasites, Rotavirus and Norwalk abdominal x-ray
 |  | 
        |  | 
        
        | Term 
 
        | What are the possible causes of diarrhea that has lasted > 2 weeks?  Notes |  | Definition 
 
        | parasites, disaccharidase, bacterial, host deficiencies, or other |  | 
        |  | 
        
        | Term 
 
        | What is the treatment for diarrhea?  Notes |  | Definition 
 
        | Fluid and electrolytes abx - especially for travelers
 Pepto bismol before eating and before bed
 Lomotil - if necessary; don't use with food poisoning
 |  | 
        |  |