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Clin Med - Strep and Staph
Streptococcus and Staphyloccocus
61
Other
Graduate
03/07/2010

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Cards

Term
Describe impetigo. Notes
Definition
Superficial infection that causes honey-colored crusts. Only epidermis is involved, so no scarring once it heals. Does not causes "sick" patient. Can be caused by streptococcus or other bacteria. Can involve the hair follicle - which makes crust more difficult to remove.
Term
How do you treat impetigo? Notes
Definition
If small spot, use topical (bacitracin). If large or if topical won't be used, use systemic oral abx.
Term
Describe cellulitis. Notes
Definition
Skin infection that is deeper than impetigo. It is not an abscess; it is firm throughout. Cellulitis is not terribly demarcated. Signs of inflammation.
Term
Describe ecthyma. Notes
Definition
Ecythema is like an impetigo infection that has gone deeper and now involves the dermis. This can cause scarring after healing. Impetigo may be the precursor.
Term
Describe lymphangitis. Notes
Definition
Inflammation of the lymph system proximal to a distal injury. Sometimes there is a breach in the skin.
Term
How do you treat cellulitis? Notes
Definition
Treat with antibiotics - penicillin. If suspect possibility of staph can treat with macrolide or sulfa drugs.
Term
How do you treat lymphangitis? Notes
Definition
Hot compresses make it feel better and resting the arm is good. Treat with abx - inpatient if septic. Follow up is key.
Term
T/F - Notes
Staph can cause lymphangitis.
Definition
True - but Strep is a more common cause.
Term
Describe folliculitis. Notes
Definition
Infection of the hair follicle. Does not have the crusting that is seen with impetigo. May have pustules. Will not see white heads or black heads - cannot squeeze material from deeper.
Term
How do you treat folliculitis? Notes
Definition
If small, may not need abx. Antiseptic. Do not shave while treating!
Term
Describe a furuncle. Notes
Definition
Deep infection in which pus is coming out of a deeper abscess. Has a core of inspissated pus (drying). May scar.
Term
How do you treat a furuncle during induration? Notes
Definition
hot compresses and abx
Term
How do you treat a furuncle once it spontaneously breaks or is fluctuant and ready to be broken open? Notes
Definition
Break open - no anesthetic needed and won't work well because of acidic wound. Remove the core.
Term
Describe a carbuncle. Notes
Definition
A collection of furuncles. These are typically found on the back of the legs or the back of the neck.
Term
How do you treat a carbuncle? Notes
Definition
Prescribe a pain med, abx, and hot compresses. Wait for furuncles to come to the surface. Cut out a 1 cm square, break up the inside, pack and leave open.
Term
Describe erysipelas. Notes
Definition
"Slapped face" rash. Fever. Firm. Septic!! Commonly on face, but can occur other places.
Term
How do you treat erysipelas? Notes
Definition
Abx, may put on IV to get ahead of this.
Term
What drugs should be used to treat pharyngitis and impetigo? Notes
Definition
Penicillin or erythromycin (macrolide)
Term
What drugs should be used to treat cellulitis and erysipelas? Notes
Definition
Penicillin or dicloxacillin
Term
What drugs do you use to treat necrotizing fasciitis or strep. toxic shock syndrome? Notes
Definition
Cindamycin (IV) and/or Penicillin
Term
What are the 5 cardinal manifestations of rheumatic fever? Notes
Definition
1. Carditis
2. Polyarthritis
3. Erythema marginatum
4. Subcutaneous nodules
5. chorea
Term
How many major manifestations of rheumatic fever must you have for diagnosis? Notes
Definition
At least 2
Term
What are the 2 most common major manifestations of rheumatic fever? Notes
Definition
carditis and polyarthritis
Term
If the patient presents with only 1 major manifestation of rheumatic fever, how many minor manifestations must the pt have?
Definition
1 major + 2 minor = diagnosis
Term
What are the possible minor manifestations of rheumatic fever? Notes
Definition
arthralgia, fever, inc. acute-phase reactants, inc. erythrocyte sed rate, ince. C-reactive protein, prolonged PR interval
Term
How do you prevent recurrent attacks of rheumatic fever? Notes
Definition
1 of the following: Penicillin, sulfadiazine, or erythromycin for allergic individuals
Term
How long is secondary rheumatic fever prophylaxis continued? Notes
Definition
At least 10 years with carditis (maybe lifelong), and at least 5 years without carditis
Term
Does long term secondary prophylaxis for rheumatic fever lead to drug resistance? Notes
Definition
There is no evidence that it does at this time.
Term
Where is staphylococcus carried? Notes
Definition
nasopharynx
Term
T/F - Notes
Staphyloccocus in the nasopharynx can cause infection in the host or in others.
Definition
True
Term
T/F - Notes
Staph usually causes an invasive, disseminated infection as opposed to a local infection.
Definition
False - usually local but can invade
Term
Why does Staph tend to complicate inflamed/traumatized tissue (ex. wounds)? Notes
Definition
surface receptors on Staph adhere to inflamed/traumatized tissue and thus complicate these areas
Term
What types of infections are commonly caused by Staph? Notes
Definition
furuncle or skin abscess
bullous impetigo
surgical wound infection
nosocomial bacteremia
acute or R sided bacterial endocarditis
hematogenous osteomyelitis
septic arthritis
pyomyositis
renal carbuncle
scalded skin syndrome
toxic shock syndrome
food-borne gastroenteritis
botryomycosis
paraspinous or epidural abscess
Term
What types of infections are less commonly caused by Staph? Notes
Definition
cellulitis
nosocomial pneumonia
brain abscess
empyema
Term
What types of infections are rarely caused by Staph? Notes
Definition
CAP
ascending UTI
meningitis
enterocolitis
Term
What is Nikolsky's sign? Notes
Definition
Where the skin slips off - as in scalded skin syndrome
Term
What are furuncles frequently mistaken for by patients? Notes
Definition
spider bites
Term
What drug do we use to treat Staph and why? Notes
Definition
Bactrim DS - sulfa drug
because Staph is getting more resistant to dicloxicillin and macrolides
Term
When should you suspect a carrier state for Staph? Notes
Definition
repeated infections
Term
How do you treat the carrier state for Staph? Notes
Definition
Mupirocin ointment intranasally bid
Rifampin plus dicloxacillin
Term
When is the best time to treat osteomyelitis? Notes
Definition
the first time that it shows - be aggressive! Don't let it come back!
Term
What are the 3 types of osteomyelitis? Notes
Definition
Hematogenous, vertebral, and focal
Term
What would the WBC count be in a patient with osteomyelitis? Notes
Definition
> 15,000

normal is about 5,000-10,000
Term
What lab tests would you run for suspected osteomyelitis? Notes
Definition
CBC/WBC, Chem profile, sed rate, C-reactive protein, bone/blood C&S, bone biopsy, plain film x-ray
Term
What are the 3 treatment options for osteomyelitis? Notes
Definition
1. Medical
2. Medical/ surgical debridement/ stabilization
3. Medical/ surgical amputation
Term
Name 3 indications for surgery in an osteomyelitis case. Notes
Definition
1. failure of medical treatment
2. soft tissue abscess
3. joint sepsis/ instability
Term
Name 4 factors that influence treatment and prognosis. Notes
Definition
1. degree of necrosis
2. condition of host
3. site and extent of involvement
4. disabling effects
Term
How do we classify osteomyelitis cases? Notes
Definition
Anatomic type 1-4 and physiologic class A-C

Anatomic type
1. medullary
2. superficial
3. localized
4. diffuse

?
A. healthy
B. immunocompromised
C. treatment worse than disease
Term
What is the most common cause of osteomyelitis? Notes
Definition
Staphylococcus aureus
Term
T/F - Notes
Staph. can cause GI infections.
Definition
True
Term
What is the definition of acute diarrhea? Notes
Definition
< 3 weeks
Term
What are the possible causes of acute diarrhea? Notes
Definition
infection, drug-related (abx, laxatives, etc), or IBD (inflammatory bowel disease such as Crohn's or UC)
Term
What is the definition of chronic diarrhea? Notes
Definition
> 3 weeks
Term
What are the possible causes of chronic diarrhea? Notes
Definition
drug-related, giardia, malabsorption, UC< tumors
Term
What causes diarrhea pathophysiologically? Notes
Definition
decreased fluid absorption
increased fluid secretion
motor changes
mucosal injury
Term
What 10 things do you need to know when a patient complains of diarrhea? Notes
Definition
1. Amount of water
2. blood
3. pus
4. time
5. cramps
6. travel
7. food history
8. contacts
9. fluid intake
10. temperature
Term
When is Giardia especially likely? Notes
Definition
1. hx of travel to mountainous areas of North America
2. travel to Russia (St. Petersburg)
3. travel to developing tropical/semitropical world
4. Contact with day care centers
Term
What are the 5 key things to note during the physical exam of the patient with diarrhea? Notes
Definition
1. hydration
2. overall appearance
3. age
4. vitals
5. abdominal exam
Term
What lab tests should be run on a patient presenting with diarrhea? Notes
Definition
Stool C&S, WBC, RBC, Ova and parasites, Rotavirus and Norwalk
abdominal x-ray
Term
What are the possible causes of diarrhea that has lasted > 2 weeks? Notes
Definition
parasites, disaccharidase, bacterial, host deficiencies, or other
Term
What is the treatment for diarrhea? Notes
Definition
Fluid and electrolytes
abx - especially for travelers
Pepto bismol before eating and before bed
Lomotil - if necessary; don't use with food poisoning
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