Term
| What are the most common causes of liver cirrhosis in the US? |
|
Definition
1) excessive alcohol use
2) chronic HCV |
|
|
Term
| What are common presenting symptoms with cirrhosis? |
|
Definition
|
|
Term
| What lab tests are characteristic for cirrhosis? |
|
Definition
| decreased albumin and prolonged prothrombin time |
|
|
Term
| What is a classic ALT AST indicator of alcoholic cirrhosis? |
|
Definition
|
|
Term
| Who is affected most common /c primary billiary cirrhosis? |
|
Definition
|
|
Term
| What is common from secondary osteoporosis in persons with primary billiary cirrhosis? |
|
Definition
1) bone pain
2) multiple fractures
3) vertebral collapse |
|
|
Term
| What are the alk phos levels usually seen in primary billiary cirrhosis? |
|
Definition
|
|
Term
| what lab test is seen in 90-95% of patients with primary billary cirrhosis? |
|
Definition
| antimitochondrial antibodies in high titer |
|
|
Term
| What is the primary cause of hepatic iron overload? |
|
Definition
| hereditary hemochromatosis |
|
|
Term
| What 2 labs are often seen with hemochromatosis? |
|
Definition
1) 80-90% saturation of serum transferin
2) serum ferritin is usually elevated |
|
|
Term
| What symptoms are usually seen by age 15 in persons with Wilson's disease |
|
Definition
| neurologic/hepatic dysfunction |
|
|
Term
| What Px finding is unique to Wilson's disease? |
|
Definition
| Kayser-Fleischer rings at periphery of cornea |
|
|
Term
| How is the diagnosis of alpha 1 antitrypsin deficiency made? |
|
Definition
| absence of alpha 1 antitrypsin protein on electrophoresis |
|
|
Term
| What are some common risk factors for NASH? |
|
Definition
1) obesity
2) diabetes mellitus
3) lipid abnormalities |
|
|
Term
| What are 4 common clinical findings associated with NASH? |
|
Definition
1) fatigue
2) weakness
3) malaise
4) hepatomegaly |
|
|
Term
| What is one of the most serious complications of cirrhosis? |
|
Definition
|
|
Term
| When is spontaneous bacterial peritonitis usually seen? |
|
Definition
|
|
Term
| What are the most common organisms associated with bacterial peritonitis? |
|
Definition
1) E. coli
2) Strep pneumoniae
3) klebsiella
4) other gram negative |
|
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