Term
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Definition
| ingestion of microorganisms, foreign substances, necrotic cells, & connective tissue by specialized cells |
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Term
| Chronic inflammation cell types |
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Definition
| monocyte/macrophages, fibrocyte, endothelial cells, lymphocytes, plasma cells. |
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Definition
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Definition
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Definition
| pink or red tinge (RBC's) |
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Term
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Definition
| mucous, damaged tissue such as lung, nose, vagina. |
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Term
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Definition
| if too much fluid, where does it go. |
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Term
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Definition
| inflammation of lymph vessels |
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Term
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Definition
| lymph nodes become enlarged (hyperplasia of immune cells, TTP) |
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Term
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Definition
| caused by endogenous pyrogens(bacteria) released into circulation. Prostaglandins are released from macrophages and cause a shift to occur in neurons in relation to cold |
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Term
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Definition
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Term
| Leukocytosis - Neutrophilia |
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Definition
| occurs during bacterial infections or an MI |
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Term
| Leukocytosis: Lymphocytosis |
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Definition
| occurs with viral infections |
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Term
| Leukocytosis (Eosinophilia) |
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Definition
| seen in allergies & parasitic infections |
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Term
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Definition
body is unable to make enough WBC's.
-seen in overwhelming infection, malnourishment, chronic debilitation. May lead to Cachexia |
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Term
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Definition
| found in skin, bone, tendon & ligament. Characteristic- builds tensile force when stretched. |
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Term
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Definition
| found in cartilage. Characteristic- surface resists shear forces, deep resists compression. |
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Term
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Definition
| found in pliable tissues such as skin, blood vessels, uterus GI tract. |
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Term
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Definition
| found in all epithelial cells except the liver. Characteristic- tensile strength to underlying structure-- basement membrane. |
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Term
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Definition
| found in anchoring filaments of lymph vessels to open them up, aids in drainage |
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Term
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Definition
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Term
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Definition
| type I collagen has decreased vascularization. |
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Term
| Secondary intention of healing |
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Definition
| Scar on top of granulation tissue. |
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Term
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Definition
| Stable cells, repair and regeneration, depends on amount of damage. Knock off a couple of cels, can still regenerate hepatocytes. |
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Term
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Definition
| Stable cells-able to regenerate but not constantly dividing |
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Term
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Definition
| kills off type I pneumocytes, basement membrane regenerates to type II then diffentiates to Type I |
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Term
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Definition
| repair with cell loss and destruction. |
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Term
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Definition
| damaged cells heal by repair only. Conn tissue scar makes cardiomyocytes hypo elastic and hypo kinetic. Once an MI then the tissue doesn't function as well. More prone to secondary complications. |
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Term
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Definition
| Permanent cells, heal by repair but not a connective tissue scar, a glial scar. Sprouting from adjacent CNS cells is possible. Brain does not regenerate, certain cells in CNS can regenerate |
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Term
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Definition
| Permanent cells- replaced by scar tissue repair. No regeneration of PNS but axon regrowth @ rate of 1 mm/day or 1"/month. Lipid debris is removed by macrophages mobilized from the surrounding tissues by Wallerian degeneration |
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Term
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Definition
| Stable cells- adjacent satellite cells can move into area and regenerate skeletal muscle BUT if cut/sliced--satellite cells don't know where to go so repair only |
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Term
| Skeletal muscle hemostasis w hematoma |
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Definition
| inflammation in the 1st phase (24-48 hours post injury) |
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Term
| Skeletal muscle proliferation |
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Definition
| phase follows w/ phagocytosis, activation of satellite cells & myofiber regeneration. (6-8 weeks post injury) |
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Term
| skeletal muscle specifics, last phase |
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Definition
| maturation involves tissue remodeling. |
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Term
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Definition
| stable cells, in the process of repair--leads to regeneration because tissue is connective tissue. Takes greater than 1 year for return to full tensile strength |
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Term
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Definition
| begins as platelets enter the tear & initiate clot formation. This happens immediately followed by inflammatory phase. (starts in 1st 72 hours after injury) |
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Term
| Tendon- Fibrin & fibronectin |
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Definition
| start cross linking to reduce bleeding. |
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Term
| Tendon-proliferative phase |
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Definition
| occurs 2-3 weeks post injury. Fibroblasts spouting collagen type III |
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Term
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Definition
| begins around week 3 after initial injury. Type III is replaced by type I. Collagen is oriented along the lines of stress & organized to resist stretch and tearing. |
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Term
| 12-16 weeks to reach a level that tendon can be stressed. |
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Definition
| maximum tension should be avoided for at least 8 weeks post tendon repair. |
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Term
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Definition
| mild pain w/in 24 hours. Mild swelling, TTP & pain when stretched. |
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Term
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Definition
| moderate pain. Stress & palpation greatly increase pain. When torn=hypermobility |
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Term
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Definition
| avulsion of tissue w/severe pain. Stress to tissue us usually painless, palpation reveals defect. Torn ligaments = instability of joint. |
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Term
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Definition
| avascular, aneural, alymphatic. After adolescence, repair only. If younger, then regeneration. |
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Term
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Definition
| stable cells. Cortical & cancellous. regeneration--fractures--easily regenerates. Is approximated by pinning, screws & plating. Immobilization period 4-8 weeks. WB 4-8 weeks |
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Term
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Definition
| Inflammatory phase- hematoma formation |
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Term
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Definition
| reparative phase-formation of a soft callus around 2 weeks post injury. Growth factors involved in repair. |
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Term
| Endochondral ossification |
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Definition
| soft to hard callus leading to fracture stability (6-12 weeks) phase 2. |
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Term
| Fx healing remodeling 3.) |
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Definition
| union persists until bone is returned to normal (may take months to years) |
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Term
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Definition
| forms between fractured bone ends |
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Term
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Definition
| occurs at the bone ends because of torn blood vessels |
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Term
| Follows necrosis after a bone fracture |
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Definition
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Term
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Definition
| blood vessels, phagocytic cells, fibroblasts-lay down new collagen, susceptible to fx again because has no bony material. |
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Term
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Definition
| no bone, not able to withstand weight bearing. |
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Term
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Definition
| lay down cartilage, forms a fibrocartilagenous callus (collar). Still not weight bearing. |
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Term
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Definition
| form new bone * replaces the cartilage callus. Forms bony hard callus. |
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Term
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Definition
| remodeled by both osteoclasts and osteoblasts over following months. More compact bone is laid down and excess bone in callus is removed. Remodeling occurs according to bone stress. |
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