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Chronic Fatigue
Pathophysiology 2
7
Health Care
Graduate
12/01/2009

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Cards

Term
Disorder type
Definition
Functional: lab tests normal, use criteria to diagnose
Term
Main diagnostic criteria
Definition
1. Severe chronic fatigue of 6 months or longer not from other conditions
2. 4 or more of other symptoms
Term
Symptoms for diagnostic criteria
Definition
1. Impairment of short term memory, concentration
2. Sore throat
3. Tender lymph nodes
4. muscle pain, multi-joint
5. headache
6. Unrefreshing sleep
7. Postexertional malaise lasting 24 hours +
Term
Cause
Definition
Immune system theory: criteria all resemble sx of a viral attack. Though no active viral replication, cytokines secreted by WBCs cause fatigue, pain, aches, nodes.
Term
Immune system theory
Definition
CFS patients usually have initial flu or virus, then come down with CFS. After flu gone, immune system fails to stop secreting cytokines and continues to cause those sx.
Term
Risk factors
Definition
Allergies, flu, mental stress (suppresses immunity)
Term
Treatment
Definition
None very effective.
Hydrocortisone
Exercise
NADH supplement: important for cellular respiration
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