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CHPT 10
Muscle Tissue
35
Biology
Undergraduate 2
10/29/2012

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Term
Cardiac Tissue
Definition
1. Automaticity
2. Variable contraction tension
3. Extended contraction time
4. Prevention of wave summation
Term
Automaticity
Definition
Contraction without neural stimulation
-Controlled by pacemaker cells
Term
Variable contraction tension
Definition
controlled by nervous system
Term
Extended Contraction Time
Definition
ten times as long as skeletal muscle
Term
Prevention of Wave Summation and Tetanic Contractions by Cell Membranes -
Definition
due to long refractory period
Term
Length-Tension Relationship:
The forcefullness of muscle contraction
Definition
depends on the length of the sarcomeres
Term
Length-Tension relationship:
When a muscle fiber is stretched
Definition
there is less overlap between the thick and thin filaments and tension (forefulness) is diminished.
Term
Length-Tension relationship:
When a muscle fiber is shortened
Definition
the filaments are compressed and few myosin heads make contact with thin filaments and tension is diminished.
Term
Slow Oxidative Fibers (SO fibers)
Definition
-least powerful type of muscle fibers
-APPEAR DARK RED = more myoglobin = stores oxygen in muscle = to make ATP
-Generate ATP mainly by AEROBIC CELLULAR RESPIRATION = USING OXYGEN
-have a SLOW SPEED OF CONTRACTION
-very resistant to fatigue
Term
Fast Oxidative-Glycolytic Fibers (FOG fivers). Glycogen = liver and muscle
Definition
-contain LARGE AMOUNTS OF MYOGLOBIN AND MANY BLOOD CAPILLARIES = DARK RED
-generate ATP by AEROBIC CELLULAR RESPIRATION
-moderately high resistance to fatigue
-speed of contraction faster = walking and sprinting
Term
Fast Glycolytic Fibers (FG fibers)
Definition
-generate the most powerful contractions
-have LOW MYOGLOBIN CONTENT = LESS OXYGEN STORAGE
-relatively few blood capillaries, few mitochondria = appear white in color
-generate ATP MAINLY BY GLYCOLOSIS = ANAEROBIC
-fibers contract strongly and quickly: fatigue quickly = weight lifting
Term
Muscle Metablolism:
MUSCLE FATIGUE
Definition
factors that contribute
-INADEQUATE RELEASE OF CALCIUM ions from the SR
-depletion of creatine phosphate
-insufficient oxygen
-depletion of glycogen and other nutrients
-buildup of lacttic acid and ADP.
-Failure of the motor neuron to release enough acetylocholine
Term
Muscle Metabolism:
Oxygen Consumption After Exercise
Definition
After exercise, heavy breathing continues and oxygen consumption remain above the resting level.
Term
Muscle Metabolism:
Excess post-exercise oxygen consumption (EPOC) = The added oxygen that is taken into the body after exercise = this added oxygen is used to RESTORE MUSCLE CELLS TO THE RESTING LEVEL in three ways..
Definition
1. to convert lactic acid into glycogen
2. to synthesize creatine phosphate and ATP
3. to replace the oxygen removed from myoglobin
Term
Control of Muscle Tension:
MOTOR UNITS
Definition
-consists of a MOTOR NEURON AND THE MUSCLE FIBERS it stimulates
-the axon of a motor neuron branches out forming NEUROMUSCLAR JUNCTIONS WITH DIFFERENT MUSCLE FIBERS
-total strength of contraction depends on SIZE OF MOTOR UNITS AND THE NUMBER THAT ARE ACTIVATED
-THE INCREASE IN CONTRACTION WITH AN INCREASE IN STIMULATION IS TERMED RECRUITMENT ie see summmation
Term
Twitch Contraction
Definition
MUSCLE FIBERS IN A MOTOR UNIT IN RESPONSE TO AN ACTION POTENTIAL
Term
Latent Period (2 msec)
Definition
a BRIEF DELAY BTWN THE STIMULUS AND MUSCULAR CONTRACTION
Term
Contraction Period (10-100 msec)
Definition
-Ca++ binds to troponin
-Myosin-binding sites on actin are exposed
-cross-bridges form
Term
Relaxation Period (10-100 msec)
Definition
-Ca++ is transported into the SR
-Myosin-binding sites are covered by tropomyosin
-myosin heads detach from actin
Term
WAVE SUMMATION
Definition
increasing tension or SUMMATION OF TWITCHES
-repeated stimulations BEFORE THE END of relaxation phase
Term
INCOMPLETE TETANUS
Definition
sustained but wavering contraction
Term
COMPLETE TETANUS
Definition
if stimulation frequency is high enough, muscle never begins to relax, and is in CONTINUOUS CONTRACTION
Term
ISOTONIC CONTRACTION
Definition
skeletal muscle CHANGES LENGTH = resulting in motion
Term
ISOMETRIC CONTRACTION
Definition
skeletal muscle develops tension, but is PREVENTED FROM CHANGING LENGTH
Term
CARDIAC MUSCLE
Definition
-STRIATED, FOUND ONLY IN HEART
-single nucleus
-no triads
-are aerobic = HIGH IN MYOGLOBIN, MITOCHONDRIA
-HAVE INTERCALATED DISCKS
-HEART CONTRACTS AS A UNIT
-GAP JUNCTIONS = ALLOW ION PASSAGE
Term
Intercalated Discs
Definition
-specialized contact points between cardiocytes
-join cell membranes of adjacent cardiocytes (gap junctions, desmosomes)
Term
Functions of Intercalated Discs
Definition
-maintain structure
-enhance molecular and electrical connections
-CONDUCT ACTION POTENTIALS
Term
Because intercalated discs link HEART CELLS MECHANICALLY, CHEMICALLY AND ELECTRICALLY...
Definition
the heart functions like a SINGLE, FUSED MASS OF CELLS.
Term
SMOOTH MUSCLE IN BODY SYSTEMS
Definition
-forms around other tissues
-in blood vessels = REGULATES BLOOD PRESSURE AND FLOW
-in reproductive and glandular systems = PRODUCES MOVEMENTS
-in digestive and urinary systems = forms SPHINCTERS AND PRODUCES CONTRACTIONS
-in integumentary system = ARRECTOR PILI MUSCLES cause "goose bumps"
Term
STRUCTURE OF SMOOTH MUSCLE
Definition
contraction LAST LONGER than skeletal muscle contraction
Term
EPINEPHRINE BOUND TO BETA-ADRENERGIC receptors on smooth muscle cells of the intestines causes them to...
Definition
RELAX
Term
EPHINEPHRINE BOUND TO ALPHA2 RECEPTORS causes the arteries to...
Definition
CONTRACT (constrict), REDUCING CIRCULATION TO THESE ORGANS
Term
ACH causes smooth muscle cells in blood vessels to...
Definition
RELAX = INCREASE BLOOD FLOW
Term
ACH acts indirectly by inducing the nearby endothelial cells to make and release NO (NITRIC OXIDE = GAS = ENTERS BY DIFFUSION ["IT CAN GO ANYWHERE IN YOUR BODY"], which then...
Definition
signals the underlying smooth muuscle cells to relax NITROGLYCERINE is converted to NO, which RELAXES BLOOD VESSELS
Term
VIAGRA inhibits...
Definition
this CYCLIC GMP PHOSPHODIESTERASE (ENZYME THAT BREAKS DOWN CYCLIC GMP). (The cyclic GMP keeps blood vessels relaxed.)
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