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chp 5
chp 5
74
Biology
Undergraduate 1
09/24/2010

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Term
epidermis
Definition

 

Composed of keratinized stratified squamous epithelium, consisting of four distinct cell types and four or five layers
Term

epidermis layers

 

[image]

Definition

corneum

lucidum

granulosum

spinosum

basale

Term
epidermis function
Definition
 acting as the body's major barrier against an inhospitable environment. It is the thinnest on the eyelids at .05 mm and the thickest on the palms and soles at 1.5 mm
Term
dermis cells types
Definition
Cell types include fibroblasts, macrophages, and occasionally mast cells and white blood cells
Term
dermis layers
Definition

papillary layer

reticular layer

Term

dermis damage

 

 striae

Definition
dermal tearing (during pregnancy) also called “stretch marks”
Term

dermis damage

 

 blister

Definition
separation of epidermal/dermal layer by a fluid-filled pocket.  Result of 2nd degree burn.
Term
dermis keloid
Definition
abnormal proliferation of connective tissue during healing of skin wounds
Term
hypodermis
Definition

 

Subcutaneous layer deep to the skin
Composed of adipose and areolar connective tissue
Term
granulosum
Definition
what is the last layer of the epidermis to receive nutrients
Term

fibrous protein that helps give the epidermis its protective properties

 

stratum basale

Definition
what is the function of keratin? where do we find it?
Term
papillary layer
Definition
where do your fingerprints come from
Term
skin color
Definition

 

MelaninCaroteneHemoglobin
Term
sabaecous glands
Definition

 

Widely distributed
Most develop from hair follicles
Become active at puberty
•secrete Sebum
Oily holocrine secretion
Bactericidal
Softens hair and skin
Term
hair
Definition

 

Filamentous strands of dead keratinized cells produced by hair follicles
Contains hard keratin which is tougher and more durable than soft keratin of the skin
Made up of the shaft projecting from the skin, and the root embedded in the skin
Consists of a core called the medulla, a cortex, and an outermost cuticle
Pigmented by melanocytes at the base of the hair
Term
nails
Definition

 

Scalelike modification of the epidermis on the distal, dorsal surface of fingers and toes
Term

functions of the integumentary sytem

 

protection

Definition

 chemical, physical, and mechanical barrier

Term

skin cancer types

 

basal cell carcinoma

Definition

 

Least malignant and most common skin cancer
Stratum basale cells proliferate and invade the dermis and hypodermis
Slow growing and do not often metastasize
Can be cured by surgical excision in 99% of the cases
Term
1st degree
Definition

(only the epidermis is damaged Symptoms include localized redness, swelling, and pain

 

Term
lanugo
Definition
 
downy coat of delicate hairs covering the fetus
Term
vernix caseosa
Definition

 substance produced by sebaceous glands that protects the skin of the fetus in the amnion

 

 

 white cheesy substance from sebaceous glands; protects skin in amnion

Term
milia
Definition
accumulations in sebaceous glands on forehead and nose
Term
45%
Definition
if patient has the front of both legs, the front of his torso and the front and back of one arm burned, what percentage of his body is burned?
Term

area Asymetrical

Border look weird

Color more tahn 1 color

Diameter bigger than a pencil eraser

Elevation

Definition
your patient asks you to look @ a mole on her shoulder. what signs would cause concern
Term
hair follicle
Definition
[image]
Term
structure of the nail
Definition
[image]
Term
epidermis
Definition
[image]
Term
rule of nines
Definition
[image]
Term
[image]
Definition
[image]
Term
epidermis cell types
Definition
Cell types include keratinocytes, melanocytes, Merkel cells, and Langerhans’ cells
Term

 

Keratinocytes
Definition

– produce the fibrous protein keratin

Term
Melanocytes
Definition

 produce the brown pigment melanin

Term
Langerhans’ cells
Definition
– epidermal macrophages that help activate the immune system
Term
Merkel cells –
Definition
function as touch receptors in association with sensory nerve endings
Term
stratum basale
Definition

 

Deepest epidermal layer firmly attached to the dermis
Consists of a single row of the youngest keratinocytes
Cells undergo rapid division, hence its alternate name, stratum germinativum
Term
stratum spinosum
Definition

 

Cells contain a weblike system of intermediate filaments attached to desmosomes
Melanin granules and Langerhans’ cells are abundant in this layer
Term
stratum granulosum
Definition

 

Thin; three to five cell layers in which drastic changes in keratinocyte appearance occurs                                        
Keratohyaline and lamellated granules accumulate in the cells of this layer
Term
stratum lucidum
Definition

Thin, transparent band superficial to the stratum granulosum
Consists of a few rows of flat, dead keratinocytes
Present only in thick skin (palm and sole)
Term
Stratum Corneum
(Horny Layer)
Definition

 

Outermost layer of keratinized cells
Accounts for three quarters of the epidermal thickness
Functions include:
Waterproofing
Protection from abrasion and penetration
Rendering the body relatively insensitive to biological, chemical, and physical assaults
Term
epidermal layers
Definition
[image]
Term
papillary layer
Definition
Areolar connective tissue with collagen and elastic fibers
Its superior surface contains peglike projections called dermal papillae
Dermal papillae contain capillary loops, Meissner’s corpuscles, and free nerve endings
Dermal ridges à epidermal ridges: fingerprints
Term

 

Reticular layer
Definition
Accounts for approximately 80% of the thickness of the skin
Collagen fibers in this layer add strength and resiliency to the skin
Elastin fibers provide stretch-recoil properties
Term

 

Melanin
Definition

 yellow to reddish-brown to black pigment, responsible for dark skin colors

Freckles and pigmented moles – result from local accumulations of melanin
Term
Carotene
Definition
– yellow to orange pigment, most obvious in the palms and soles of the feet
Term
Hemoglobin
Definition
 reddish pigment responsible for the pinkish hue of the skin
Term

 

Cyanosis

Definition

blue when deoxygenated blood due to heart failure or respiratory disorders

Term
Erythema/redness
Definition

– embarrassment, fever, hypertension, inflammation, allergy

Term
Pallor/blanching –
Definition
fear, anger, anemia, low BP
Term
Jaundice
Definition

yellow – liver disorder (bilirubin from bile)

Term
Bronzing
Definition

 Addison’s, hypofunction of adrenal cortex

Term
Bruises
Definition
 escaped blood/hematomas
Term

type of sweat glands

 

 

Eccrine sweat glands
Definition
 – found in palms, soles of the feet, and forehead
Term
Apocrine sweat glands
Definition
– found in axillary and anogenital areas
Term
Ceruminous glands
Definition
modified apocrine glands in external ear canal that secrete cerumen
Term
Mammary glands
Definition
– specialized sweat glands that secrete milk
Term
hair functions
Definition

 

Helping to maintain warmth
Alerting the body to presence of insects on the skin
Guarding the scalp against physical trauma, heat loss, and sunlight
Term
Hair Follicle
Definition

 

Root sheath extending from the epidermal surface into the dermis
Deep end is expanded forming a hair bulb
A knot of sensory nerve endings (a root hair plexus) wraps around each hair bulb
Bending a hair stimulates these endings, hence our hairs act as sensitive touch receptors
Term

 

Vellus
Definition

pale, fine body hair found in children and the adult female

Term
Terminal
Definition
coarse, long hair of eyebrows, scalp, axillary, and pubic regions
Term

 

True, or frank, baldness
Definition
Genetically determined and sex-influenced condition
Male pattern baldness – caused by follicular response to DHT
Term

functions of the igumentary system

 

 

 

Metabolic functions
Definition

– synthesis of vitamin D in dermal blood vessels

Term
functions of the integumentary sytem
Cutaneous sensation –
Definition
exoreceptors sense temperature, touch and pain
Term

functions of the integumentary system

 

Body temperature regulation is accomplished by:

Definition
Dilation (cooling) and constriction (warming) of dermal vessels
Increasing sweat gland secretions to cool the body
Term
Blood reservoir
Definition
 skin blood vessels store up to 5% of the body’s blood volume
Term
Excretion
Definition
limited amounts of nitrogenous wastes and salt are eliminated from the body in sweat
Term

skin cancer types

 

squamous cell carcinoma

Definition

 

Arises from keratinocytes of stratum spinosum
Arise most often on scalp, ears, and lower lip
Grows rapidly and metastasizes if not removed
Prognosis is good if treated by radiation therapy or removed surgically
Term

skin cancer types

 

melanoma

Definition

 

Cancer of melanocytes is the most dangerous type of skin cancer because it is:
Highly metastatic
Resistant to chemotherapy
Term

melanoma characteritics

 

A Asymmetry

Definition
the two sides of the pigmented area do not match
Term

melanoma characteristics

 

B border

Definition
:  Border is irregular and exhibits indentations
Term

melanoma characteristics

 

C color

Definition
  (pigmented area) is black, brown, tan, and sometimes red or blue
Term

melanoma characteristics 

D: 
Definition
Diameter is larger than 6 mm (size of a pencil eraser)
Term

melanoma characteristics

 

elevation

Definition
is it elevated
Term

2nd degree

 

Definition

 

– epidermis and upper regions of dermis are damaged
Symptoms mimic first degree burns, but blisters also appear
Term
3rd degree burn
Definition

 

– entire thickness of the skin is damaged
Burned area appears gray-white, cherry red, or black; there is no initial edema or pain (since nerve endings are destroyed)
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