Term
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Definition
PSNS These meds influence the activity of cholinergic receptors, that mediate or control responses to acetylcholine.
This will affect the PSNS and the Pre-ganglionic activity of the SNS as well as the skeletal muscle system through the somatic motor system.
REST AND RELAX |
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Term
| cholinergic receptor subtypes |
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Definition
NicotinicM (Neuromuscular)
NicotinicN (ganglionic)
Muscarinic |
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Term
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Definition
| sweat galnds, blood vessels and all organs regulated by PSNS. - chronotropic (remem to check HR <60 hold), in sweating/secretion, inc bronchial secretions. smooth muscle contraction (constric in bronchi, inc tone and motility in GI smooth muscle and bladder), miosis |
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Term
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Definition
| CXN on the ciliary muscles pupil getting smaller. |
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Term
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Definition
Bethanechol (Urecholine)
Used most often with urinary retention, gastroesophageal reflux dz.,
Pilocarpine
Used mainly with glaucoma
Muscarine (not on the market today)
Found in most poisonous mushrooms |
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Term
| Muscarinic Agonists- nursing considerations |
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Definition
Take the HR before administering
If administering via eye drops then apply inter-canthus pressure
Keep atropine on hand when using these types of meds |
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Term
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Definition
These will block the action of acetylcholine at the muscarinic sites
Also known as anti-muscarinic, muscarinic blockers, and anticholinergic meds.
The opposite affect of the muscarinic agonist is expected
MAIN REASON IS TO SPEED UP HR |
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Term
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Definition
0.5 mg standard dose the main med in this class, leads to:
inc HR (main usage)
inc gland secretions
Relaxation of the bronchi
dec tone of the bladder and GI tract
Mydriasis (big pupil) |
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Term
| what must you have to get atropine |
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Definition
| symptomatic bradycardia. change of level of consciousness. low CO, not enough o2, restless, skin turning blue, pins needles, low CRefill, |
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Term
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Definition
Dry mouth
Blurred vision
Elevated intraocular pressure
Urinary retention
Constipation
Tachycardia
Asthma exacerbation
anti-cholergenic effect- DRYING |
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Term
| other anti-muscarinic meds |
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Definition
Scopolamine (used for motion sickness)
Ipratropium Bromide (Atrovent): used for maintenance of COPD and asthma, short onset and long acting.
Dicyclomine: used for a spastic colon
Oxybutynin (Diropan) and Tolterodine (Detrol): used for overactive bladder. |
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Term
| neuromuscular blocking agents |
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Definition
These block acetylcholine from activating nicotinicM receptors
The result is:
Profuse body-wide smooth muscle relaxation (paralysis)
Hypotension
HAVE TO BE SEDATED. EVERYTHING IS PARALYZED- watch BP |
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Term
intermediate acting Neuromuscular blocking agents:
meds |
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Definition
Pancuronium (Pavulon)
Vecuronium (Norcuron) |
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Term
ultra short acting Neuromuscular blocking agents:
meds |
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Definition
Succinylcholine (Anectine)
peds- displaces potassium - hypokalemia |
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Term
Neuromuscular blocking agents:
meds precautions |
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Definition
NEVER GIVE ANY OF THESE MEDICATIONS UNLESS THE PATIENT IS ALREADY INTUBATED!!!!!!!
NEVER GIVE THESE MEDICATIONS OFF OF THE SURGICAL OR INTENSIVE CARE FLOORS!!!!!!!!
The patient is awake, yet cannot move/breath.
If they are going to be on this, give them a sedative as well. |
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Term
| Neuromuscular blocking agents: uses |
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Definition
Conjunction with ventilatory support
Prior to intubation
Muscle relaxation during surgery |
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Term
| Neuromuscular blocking agents: SE/AR |
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Definition
Prolonged apnea
Malignant hyperthermia
Post-op pain
Hyperkalemia (succinylcholine can cause the tissues to release potassium) |
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Term
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Definition
| sickness level in a population |
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Term
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Definition
| death level in a population |
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Term
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Definition
| uncontrolled rising in temp. |
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