Term
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Definition
- competitive inhibitor at all 5 receptors
- Different response based off dose
- Uses: antidote to AChE ihibitors, retinal exam, adjivant in anesthesia
- adverse effects: mydriasis, blurred vision, constipation, urinary retention, dry mouth, hot skin |
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Term
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Definition
| Slight bradycardia, followed by tachycardia, dry mouth, thirst, inhibition of sweating, slightly dilated pupils |
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Term
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Definition
| Dilated pupils (mydriasis), blurred near vision (cycloplegia) |
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Term
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Definition
| Dry and hot skin, urinary retention |
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Term
| 10 mg or more of atropine |
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Definition
| Cardiovascular depression, coma, respiratory failure |
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Term
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Definition
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Term
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Definition
- blocks all 5 muscarinic recepotrs
- for treatment of motion sickness
- similar adverse effects to atropine, with more CNS depression |
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Term
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Definition
- blocks M3
- treats Asthma, COPD |
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Term
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Definition
- blocks M3
- treats IBS, can be used for urinary incontinence |
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Term
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Definition
- blocks M3
- used for urinary incontinence
- adverse effects- dry mouth |
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Term
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Definition
- blocks M3
- dilates pupil for exam
- adverse effects- blurred near vision |
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Term
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Definition
- competitive nicotinic receptor blocker
- ganglionic blocker
- used in patches for smoking cessation |
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Term
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Definition
| - tachycarida, increased BP, broncial, calivary, and sweat secretions |
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Term
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Definition
- blocks Nm (competitive blocker)
- used for muscle relaxation |
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Term
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Definition
- blocks Nm (competitive blocker)
- used for muscle relaxation
- adverse effects: histamine release, allergy |
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Term
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Definition
- depolarizing blocker of Nm
- Produces a persistent partial depolarization by not allowing the threshold of AP to be achieved
- 2 phases: I- Produces persistent partial depolarization by not allowing the threshold for AP to be achieved. This is followed by desensitization of nicotinic receptors to action of ACh and closing of Na channels leading to paralysis of muscle.
- closes Na channels
- muscle relaxation |
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Term
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Definition
| trimethaphan, hexamethonium |
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Term
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Definition
| excessive salvation, to produces cycloplegia |
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Term
| contraindications of cholinergic antagonists |
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Definition
| glaucoma, GI obstruction or atony |
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Term
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Definition
ganglionic inhibitor
binds to Na channel to prevent Na influx |
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