Term
| T/F: chlamydia are obligate intracellular bugs. |
|
Definition
|
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Term
|
Definition
|
|
Term
| do chlamydia have a peptidoglycan layer? |
|
Definition
|
|
Term
| what are the two morphologically distinct forms of chlamydia? |
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Definition
| Elementary Body (EB) & Reticulate Body (RB) |
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|
Term
| which form is metabolically active? |
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Definition
| Reticulate Body (hence why it's twice as big as the EB) |
|
|
Term
| how does chlamydia avoid destruction in a macrophage? |
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Definition
| prevents fusion of phagosome with lysosome |
|
|
Term
| where does chlamydia first differentiate from an EB to an RB? |
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Definition
| within the endosome/inclusion (the thing in which they entered the host cell). |
|
|
Term
| when do RBs redifferentiate BACK into EBs? |
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Definition
| once they reproduced enough and filled the vacuole they were sitting in. The EBs then exit after lysis of host cell and infect other cells. |
|
|
Term
| name 3 species of Chlamydia: |
|
Definition
| trachomatis, psittaci, pneumoniae |
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|
Term
| which species has a method of transmission from sexual contact? |
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Definition
|
|
Term
| which species has a method of transmission from bird droppings? |
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Definition
|
|
Term
| which species has a method of transmission from person to person? |
|
Definition
|
|
Term
| what is the most common cause of STIs? |
|
Definition
|
|
Term
| what genital infections might C. trachomatis cause in women? |
|
Definition
| pelvic inflammatory disease (although nearly 80% of women are asymptomatic) |
|
|
Term
| what is Reiter's Syndrome? |
|
Definition
| Autoimmune disease caused by cross-reactivity of antibodies to C. trachomatis |
|
|
Term
| what major infection from C. trachomatis occurs in newborns? |
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Definition
|
|
Term
| T/F: Endemic trachoma (conjunctivitis) have the same serotypes as those strains that cause genital infections |
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Definition
|
|
Term
| how is endemic trachoma (conjunctivitis) spread? |
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Definition
|
|
Term
| what effects may result on the eye from conjunctivitis (not the newborn type)? |
|
Definition
| scarring and loss of vision |
|
|
Term
| is Lymphogranuloma Venerum (LGV) sexually transmitted? |
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Definition
|
|
Term
| which lymph nodes are involved in LGV? |
|
Definition
|
|
Term
| what is a zoonotic infection? |
|
Definition
| passed from animals to humans |
|
|
Term
| what does C. psittaci induce? |
|
Definition
|
|
Term
| which bug can be the cause of walking pneumonia? |
|
Definition
|
|
Term
| what is the "gold standard" for diagnosing Chlamydia infections? |
|
Definition
| culture them in McCoy cells (host epithelial cells) |
|
|
Term
| are chlamydia free-living? |
|
Definition
| no, they are obligate intracellular bugs |
|
|
Term
| what are the smallest, free-living bacteria? |
|
Definition
|
|
Term
| Mycoplasma pneumoniae is a pathogen in which portion of the respiratory tract (upper or lower)? |
|
Definition
|
|
Term
| which system is infected by Mycoplasma genitalium and Ureaplasma? |
|
Definition
|
|
Term
| T/F: Mycoplasma form pleomorphic filaments |
|
Definition
|
|
Term
| do mycoplasma have a peptidoglycan layer? |
|
Definition
|
|
Term
| do mycoplasma contain cholesterol in their membrane? |
|
Definition
| YES, they are the only bugs that do! |
|
|
Term
| where does Mycoplasma attach to host? |
|
Definition
| on the cilia in trachea (bronchi and bronchioles) |
|
|
Term
| what distinguishes Ureaplasma urealyticum from Mycoplasma? |
|
Definition
| it produces a lot of urease |
|
|
Term
| are mycoplasma intracellular or extracellular? |
|
Definition
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