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Chemistry- Liver Function
Test 2
19
Medical
Undergraduate 4
09/16/2009

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Cards

Term
What is the functional unit of the liver?
Definition
lobules
Term
What makes up a portal triad?
Definition
hepatic artery, portal vein, bile duct
Term
What is the excretory function of the liver?
Definition
Bile formation and excretion into intestine
Term
What is the fuction of Kupffer cells?
Definition
immune mechanisms, phagocytosis in detoxification and protective functions
Term
The liver converts carotene to what?
Definition
vitamin A
Term
Where is prothrombin synthesized?
Definition
in the liver/ parenchymal cells
Term
What two coagulation factors are produced in the liver?
Definition
fibrinogen, prothrombin
Term
What three vitamins are stored in the liver?
Definition
A, D, B12
Term
What happens to bilirubin in the liver?
Definition
It's converted to bilirubin diglucuronide (conjugated bilirubin)
Term
How is bilirubin excreted?
Definition
As urobilin in feces and urobilinogen and bilirubin in urine
Term
Which form of bilirubin is water soluble- conjugated or unconjugated?
Definition
conjugated
Term
What method is used to measure bilirubin (direct and indirect)?
Definition
Jendrassik-Grof
Term
In the Jendrassik-Grof method, what reacts with bilirubin to form a colored compound (azobilirubin)?
Definition
diazotized sulfanilic acid
Term
What two primary bile acids are produced from bilirubin in the liver?
Definition
cholic acid and chenodeoxycholic acid
Term
Where is bile stored?
Definition
in the gall bladder
Term
What does jaundice indicate?
Definition
liver disease
Term
Which type of jaundice is characterized by unconjugated hyperbilirubinemia with no bilirubin in urine?
Definition
prehepatic/hemolytic jaundice
Term
Obstruction of bile duct would be what kind of jaundice?
Definition
posthepatic jaundice
Term
What kind of jaundice is caused by gall stones?
Definition
posthepatic jaundice
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