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Chemistry- fluid and electrolyte balance
test 3
37
Medical
Undergraduate 4
10/13/2009

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Cards

Term
What portion of body water is in intracellular fluid?
Definition
2/3
Term
What portion of body water is in extracellular fluid?
Definition
1/3
Term
What portion of extracellular fluid is in plasma?
Definition
1/3
Term
What portion of extracellular fluid is interstitial fluid?
Definition
2/3
Term
What two factors affect the distribution of body water?
Definition
osmolality and protein
Term
what regulates movement of fluid between interstitial space and intracellular space through cell wall?
Definition
osmolality
Term
what regulates movement of fluid between plasma and interstitial space through capillary wall?
Definition
osmolality and hydrostatic blood pressure
Term
In hypotonic fluid loss, what is lost?
Definition
just water.
Term
in isotonic fluid loss, what is lost?
Definition
water and sodium
Term
What part of the body responds to water deficit?
Definition
hypothalamus
Term
What two things does the hypothalamus do in response to water deficit?
Definition
activates thirst sensation, secretes ADH
Term
What kind of IV would you use to increase blood volume?
Definition
albumin or plasma expander
Term
what disorder of volume excess doesn't cause edema formation?
Definition
SIADH- syndrome of inappropriate ADH secretion
Term
What are the two disorders of volume excess that cause edema formation?
Definition
nephrotic syndrome, congestive heart failure
Term
Which causes more serious problems- sodium depletion or water depletion?
Definition
sodium depletion
Term
what is the most abundant cation in extracellular fluid?
Definition
sodium- 90% of all extracellular cations
Term
what is hypernatremia?
Definition
elevated sodium in blood
Term
What are the three causes of hypernatremia?
Definition
decreased water intake, increased water loss, osmotic diuresis
Term
In renal hypernatremia, what happens to urine osmolality?
Definition
it's low or normal
Term
what happens to urine osmolality in extrarenal hypernatremia?
Definition
it is increased.
Term
which is more common, hypernatremia or hyponatremia?
Definition
hyponatremia
Term
What causes hyponatremia in conjunction with volume depletion?
Definition
vomiting, diarrhea, diuretics
Term
what causes hyponatremia in conjunction with euvolemia?
Definition
psychogenic polydypsia, SIADH
Term
What causes hyponatremia in conjunction with volume excess?
Definition
congestive heart failure, nephrotic syndrome
Term
What condition would you see pseudohyponatremia?
Definition
multiple myeloma
Term
what is hyperkalemia?
Definition
elevated potassium in blood
Term
what could cause pseudohyperkalemia? 4 things
Definition
increased platelet count, increased wbc count, hemolysis, ischemic blood draw
Term
which has higher potassium, serum or plasma?
Definition
serum
Term
What is hypokalemia?
Definition
decreased potassium in blood
Term
In the ion-selective electrode method for measuring potassium, what kind of membrane binds potassium?
Definition
valinomycin membrane
Term
what is the effect of HCO3 loss on chloride?
Definition
it causes hyperchloremia
Term
what is the effect of HCO3 excess on chloride?
Definition
hypochloremia
Term
What is the effect of compensated respiratory acidosis or metabolic alkalosis on chloride?
Definition
hypochloremia
Term
What is the formula for anion gap?
Definition
(Na + K) - (HCO3 + Cl)
Term
What is the normal range for anion gap?
Definition
10-20 or 7-16 if not using K
Term
What does increased anion gap indicate?
Definition
presence of increased concentration of anions other than HCO3 and Cl.
Term
What does decreased anion gap indicate?
Definition
lab error
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