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Chemistry- Calcium and Related Constituents
test 4
32
Health Care
Undergraduate 4
10/27/2009

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Cards

Term
What is the active form of calcium?
Definition
ionized calcium
Term
What percent of plasma calcium is ionized?
Definition
45%
Term
What percent of body calcium is in bones and teeth?
Definition
99%
Term
What percent of phosphorus is in hydroxyapatite?
Definition
85%
Term
Phosphorus participates in cell functions such as:
Definition
energy metabolism and gene replication
Term
High levels of phosphorus are associated with what kind of disease ?
Definition
cardiovascular disease
Term
What is the effect of PTH on plasma total and ionized calcium?
Definition
increases calcium
Term
What is the effect of PTH on inorganic phosphate?
Definition
PTH decreases inorganic phosphate
Term
Where is PTH synthesized?
Definition
parathyroid glands
Term
What are the 2 active forms of PTH?
Definition
intact and N-terminal.
Term
What hormone increases both Calcium and Phosphorus levels?
Definition
Vitamin D
Term
What hormone decreases both calcium and phosphorus levels?
Definition
calcitonin
Term
What hormone increases calcium and decreases phosphorus?
Definition
PTH
Term
What is the half life of parathyroid hormone?
Definition
3-4 minutes
Term
Which form of vitamin D is the dietary form found in fish, plants and fungus?
Definition
Vitamin D2; ergocalciferol
Term
Which form of Vitamin D is produced by photosynthesis in the skin from exposure to sunlight?
Definition
Vitamin D3/ cholecalciferol
Term
What is the active form of vitamin D?
Definition
1,25 dihydroxyvitamin D
Term
Which form of vitamin D is tested to assess vitamin D stores?
Definition
25 hydroxyvitamin D
Term
3 methods to measure vitamin d stores?
Definition
immunoassay; hplc; lcmsms
Term
2 causes of tetany
Definition
calcium deficiency; magnesium deficiency
Term
2 methods to measure total calcium?
Definition
colorimetric, atomic absorption
Term
method used to measure ionized calcium?
Definition
ion-selective electrode
Term
2 methods to measure magnesium?
Definition
colorimetric, atomic absorption
Term
What chemical is used to measure inorganic phosphate?
Definition
molybdate
Term
how is inorganic phosphate measured?
Definition
colorimetric method using molybdate
Term
How is PTH measured?
Definition
immunoassay
Term
How is calcitonin measured?
Definition
immunoassay
Term
What are the cells that synthesize the calcified matrix in bone?
Definition
osteoblasts
Term
What is the name for mature osteoblasts embedded in matrix?
Definition
osteocytes
Term
What cells contain enzymes to demineralize and digest bone?
Definition
osteoclasts
Term
4 bone formation markers
Definition
bone specific alkaline phosphatase; osteocalcin; PICP; PINP
Term
5 bone reabsorption markers?
Definition
Tartrate resistant acid phosphatase (TRAP); hydroxyproline; telopeptides; pyridinoline; deoxypiridinoline
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