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Chemical Senses
Basic Neuro: Chemical Senses
58
Medical
Professional
03/20/2012

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Cards

Term
Posterior tongue region
Definition
Location of Bitter taste
Term
Posterior lateral tongue region
Definition
Location of Sour taste
Term
Tip of the tongue
Definition
Location of Sweet/Umami taste
Term
Tip and anterior lateral region of the tongue
Definition
Location of Salty taste
Term
10mM
Definition
Threshold for salty (NaCl)
Term
20mM
Definition
Threshold for sweet (sucrose)
Term
O.008mM
Definition
Threshold for bitter (quinine)
Term
0.0001mM
Definition
Threshold for bitter (strychnine)
Term
2mM
Definition
Threshold for sour (citric acid)
Term
45
Definition
age when taste buds begin to decline
Term
25
Definition
percent of taste buds on foliate
Term
25
Definition
percent of taste buds on fungiform
Term
50
Definition
percent of taste buds on circumvallate
Term
Where are the most taste buds located on the tongue?
Definition
circumvallate
Term
posterior medial region of the tongue
Definition
circumvallate
Term
posterior lateral region of the tongue
Definition
foliate
Term
anterior lateral region of the tongue
Definition
fungiform
Term
tea, cranberries
Definition
astringents
Term
hot pepers, ginger
Definition
pungents
Term
mixtures of tastes
Definition
can be perceived as a separate taste
Term
70
Definition
percent of medium tasters
Term
15
Definition
percent of non-tasters
Term
15
Definition
percent of supertasters
Term
2x more taste buds
Definition
supertasters
Term
increased perception of bitter taste (ie PROP, PTC)
Definition
supertasters
Term
strong aversion to essential flavonoids like brussel sprouts, kale
Definition
supertasters
Term
Amiloride-sensitive Na channel
Definition
Salt
Term
H+ sensitive TRP channel
Definition
Acids (sour)
Term
TRP channel is similar to
Definition
Nociceptors
Term
T2R / Gustducin / PLC / IP3 / TRPM5 channel
Definition
Amino acids
Term
T1R2 / T1R3 / G protein
Definition
Sweet
Term
neurons go to specific areas for type of taste and location of taste
Definition
Labeled line coding
Term
Geniculate ganglion
Definition
CN VII, ant 2/3 tongue
Term
Petrosal gangion
Definition
CN IX, Pos 1/3 tongue
Term
Nodose ganglion
Definition
CN X, pharynx
Term
Taste buds --> (one of three nerves and ganglion) --> ?
Definition
gustatory area of solitary nucleus
Term
Taste buds --> (one of three nerves and ganglion) --> Solitary nucleus --> ?
Definition
VPM
Term
Taste buds --> (one of three nerves and ganglion) --> Solitary nucleus --> VPM -> ?
Definition
gustatory cortex (ant insula-frontal operculum) also called the postcetral parietal cortex
Term
compared to a rat we have very _____ olfactory receptor cells and a ______ area of olfatory epithelium
Definition
few, small
Term
is a G protein coupled receptor
Definition
oderant receptor proteins
Term
mice have 1500 expressed oderant receptor protein genes humans only have
Definition
400
Term
G-olf protein increases
Definition
cAMP in olfactory cells
Term
G-olf cascade turns on
Definition
Na/Ca channel (in), Ca gated Cl channel (out), and Na/Ca exchanger (Ca out and Na in)
Term
slow adaptation
Definition
50% olfactory receptor cells depolarize in first second
Term
we know that smell goes away after about a
Definition
minute or so
Term
we have low threshold conc for
Definition
noxious chemicals to detect them at low levels
Term
there are distinct cortical regions to detect
Definition
certain smells
Term
terminate in globs, glomeruli
Definition
Bipolar olfactory cells
Term
major projection from glomeruli
Definition
Mitral cells
Term
secondary projection from glomeruli, may sharpen signal in mitral cells
Definition
Tuft cells
Term
local lateral inhibition on mitral cells
Definition
Granule cells
Term
no thalmic relay
Definition
in olfactor signal transduction
Term
unable to small a certain odorant
Definition
Anosmia
Term
lead to salivation digestive processes
Definition
aroma
Term
gag reflex
Definition
noxious smells
Term
synchronization
Definition
reproductive and endocrine
Term
species specific (vomeronasal organ)
Definition
pheromones
Term
fMRI studies when males and females are exposed to androgens and pheromones
Definition
support that we can detect pheromones
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