Term
|
Definition
1-2 days
coagulation & infiltration of cells
(platelets, neutrophils, macrophages) |
|
|
Term
| Proliferation/new tissue formation |
|
Definition
3-4 days after injury
*Fibroblasts
collagen synthesis, epithelialization, contraction of wound, cellular differentiation |
|
|
Term
| Biochemical mediators of phase II |
|
Definition
| TGF-B, Angiogenesis factors, MMPs |
|
|
Term
|
Definition
| stimulates fibroblasts to secrete procollagen |
|
|
Term
|
Definition
| Stimulate vasclar endothelial cells to form capillary beds. |
|
|
Term
|
Definition
| Degrade and remodel extracellular matrix proteins |
|
|
Term
|
Definition
| secrete collagen and other conective tissue proteins |
|
|
Term
|
Definition
| specialized cells responsible for wound contraction |
|
|
Term
| Remodeling and maturation |
|
Definition
Continuation of cellular differentiation, scar tissue formation, scar remodeling
*Fibroblasts are main cell of remodeling |
|
|
Term
|
Definition
| Stimulates BC ad fibroblast growth |
|
|
Term
|
Definition
| Causes tumor cytotoxicity and induces fever |
|
|
Term
| Mediators of inflammation |
|
Definition
| Prostaglandins and Leukotrienes |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Histamine-like effects & increased vascular permeability |
|
|
Term
|
Definition
| Prevent viruses from infecting host cells |
|
|
Term
| Acute inflammation (systemic effects) |
|
Definition
| Fever caused by release of IL-1 by neutrophils and macgrophages |
|
|
Term
|
Definition
| Lymphocytic & macrophagic infiltration |
|
|
