Term
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Definition
| Microbes that have therapeutic use. |
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Term
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Definition
| Make whit and red blood cells. |
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Definition
| Epithelial cells covered with mucus. |
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Term
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Definition
| Molecules that damage microbial membranes. |
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Definition
| Breaks down peptidoglycan. |
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Term
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Definition
| Antimicrobial peptide produced by paneth cells. |
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Term
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Definition
| The aggregate microbial population that inhabits a person/physical area. |
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Term
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Definition
| A type of bacteria that can colonize after antibiotic overuse destroys the normal flora. |
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Term
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Definition
| Blood borne proteins that tag pathogens or attack them directly. |
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Term
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Definition
| Engulf bacteria, kill virus infeced cells or attack them directly. |
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Definition
| Process by which extracellular material is taken up. |
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Term
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Definition
| Local accumulation of fluid and cells involved in the immune response. |
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Term
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Definition
| Movement of cells and fluids into connective tissue. |
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Term
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Definition
| Signalin molecules of innate and adaptive immunity involved in inflammation and other immune responses. |
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Term
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Definition
| Adhesion molecules on leukocytes and endothelial cells. |
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Term
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Definition
| Inflammation gone wrong. Results from the body's systemic over-response to infection. |
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Term
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Definition
| Phathogen recognizing lymphocyte is amplified. |
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Term
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Definition
| How a lymphocyte can remember a pathogen after coming in contact with it once. |
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Term
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Definition
| Can differentiate into any other type of cell. |
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Term
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Definition
| Any white or red blood cell. |
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Term
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Definition
| Neutrophils, Eosinophils, Basophils, Monocyte/Macrophage, Dendritic, Mast Cells |
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Term
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Definition
| most abundant, phagocyte, effector cells of innate immunity, short-lived pus |
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Term
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Definition
| worms/intestinal parasites, amplify inflammation, Bind IgE, very toxic-pathogen and host, chronic asthma |
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Term
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Definition
| rare, unknown function, Bind to IgE |
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Term
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Definition
| Circulate in blood, bigger than PMLs, look similar, immature form of macrophage. |
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Term
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Definition
| Scavengers, phogcytose pathogens, cells, and debris, secrete cytokines |
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Term
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Definition
| Star-shaped cell found in tissue, cellular messenger adn carries cargo, dendrites are the main feature, activate T cells in the lymph node |
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Term
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Definition
| Connective tissue, granules, degranulation major contributer to inflammation and allergies. |
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Term
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Definition
Large lymphocytes-NK cells
Small lymphocytes-B and T cells |
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Term
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Definition
| large lymphocyte with granular cytoplasm, effector cell of innate immunity |
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Term
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Definition
| Kill viral infected cells, secrete cytokines that interfere with virus infections |
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Term
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Definition
| Adaptive IR, small and immature, activated by pathogen, B and T cells |
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Term
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Definition
| Megakaryocyte, erthrocyte |
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Term
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Definition
| Giant nucleus, resident of bone marrow, fusion of precursor cells, fragments to make platelets. |
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Term
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Definition
| gas transport, Infected by Plasmodium falciparum |
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Term
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Definition
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Term
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Definition
| Thoracic duct, lymphatic vessels, lymph nodes |
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Term
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Definition
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Term
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Definition
| Site of T cell development |
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Term
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Definition
| The site of WBC productionx |
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Term
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Definition
| Blood filtering organ, removes old/damaged red cells. |
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Term
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Definition
| Gut-associated lymph tissue. |
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Term
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Definition
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Term
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Definition
| A collection of proteins that work together to tag pathogens for opsonization, destruction, and recruit inflammatory molecules. |
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Term
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Definition
| Activation of zymogens and amplification of signal. |
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Term
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Definition
| Attachement of complement to pathogen surface. |
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Term
| Alternative Complement Pathway |
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Definition
| Pathogen surface creases local environment conducive to complement activation. |
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Term
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Definition
| Mannose-binding lectin binds to pathogen surface. |
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Term
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Definition
| C-reactive protein or antibody binds to specific antigen on the pathogen surface. |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Complement Control Proteins |
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Definition
| Properdin, Factor H and I, and CD59 |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Binds to MAC and stops polymerization. |
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Term
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Definition
| decay-accelearting factor |
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Term
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Definition
| Membrane co-factor protein |
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Term
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Definition
| Is on a macrophage and binds to C3b on pathogen. |
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Term
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Definition
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Term
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Definition
| Induce inflammatory response. Bind to receptors on phagocytes, mast cells, neutrophils adn endothelial cells. |
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Term
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Definition
| Increase vascular permeability and increases access to bacteria adn recruits immune cells. |
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Term
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Definition
| Caused by anaphylatoxins to mast cells and basophils |
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Term
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Definition
| release increases vasopermeability. |
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Term
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Definition
| Includes plasma enzymes and platelets. |
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Term
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Definition
| Inactivate bacterial proteases. |
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Term
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Definition
| Antimicrobial peptides that are 35-40 amino acids long. |
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Term
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Definition
| Punch holes in membranes. |
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Term
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Definition
| neutrophils and paneth cells |
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Term
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Definition
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Term
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Definition
| Provide host defense against microbes in the small intestine. |
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Term
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Definition
| long-lived, reside in tissue, early response |
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Term
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Definition
| Receptors and plasma proteins that recognize carbohydrates. |
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Term
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Definition
| recognizes negatively charged ligands |
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Term
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Definition
| Mannose receptor, Glucan receptor, and CD14 |
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Term
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Definition
| Innate receptor family with ability to detect and signal presence of pathogens. |
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Term
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Definition
| The pathogen-recognition domain is a repeating unit (extracytoplamic) |
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Term
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Definition
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Term
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Definition
| Recognizes LPS with help from MD2 adn CD14, adn initiates kinase cascade that results in transcription factor translocation. |
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Term
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Definition
| Helps TLR4 recognized LPS. |
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Term
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Definition
| Transcription factor involved in initiating the kinase cascade. |
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Term
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Definition
| IKKy x-chromosome gene that helps in bacterial infectiosn. |
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Term
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Definition
| Help defend agains viral and intracellular bacteria. |
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Term
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Definition
| Inflammatory cytokines, helps defend againgst extracellular bacteria. |
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Term
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Definition
| Inflammatory cytokines, help defend against extracellular bacteria. |
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Term
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Definition
| cytokines that are chemoattractants. |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
| large family binds to proteins |
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Term
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Definition
| Passage of cell through gaps in the blood vessel endothelial cells. |
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Term
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Definition
| Includes P-selectin and S-Lewis |
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Term
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Definition
| Endothelial cell molecule involved in rolling adhesion. |
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Term
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Definition
| Leukocyte molecule involeved in rolling adhesion. |
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Term
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Definition
| Endothelial cell thigh binding adhesion. |
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Term
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Definition
| Leukocyte involved in tight binding adhesion and diapedesis. |
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Term
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Definition
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Term
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Definition
| secretion of plasma protein from hepatocytes |
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Term
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Definition
| Involved in acute-phase response |
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Term
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Definition
| 15-18 binding sites, does not bind to single mannose residues on human cells but multiple residues on pathogens. |
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Term
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Definition
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Term
| Classical C3 convertase, C4b2a |
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Definition
| Formed by C2a binding to surface of C4b, it also cleaves C3 |
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Term
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Definition
| Binds to phosphocholin on pathogen, results in convergence of classical and lectin pathways. |
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Term
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Definition
| Respond to viral infected cells by changing expression of host genes. |
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Term
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Definition
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Term
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Definition
| activates sectreiong of cytokines by Natural killer cells. |
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Term
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Definition
| Sectreted to activate macrophages. |
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Term
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Definition
| Response caused by Type I Interferons. |
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Term
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Definition
| Response caused by Type 1 interferon. |
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