Term
| Primary & recurrent treatment of cold sores |
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Definition
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Term
| Treatments for recurrent cold sores |
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Definition
| Acyclovir, Famciclovir, Penciclovir, and valacyclovir 5 days |
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Term
| Genital and anal HSV infection treatment |
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Definition
| Acyclovir, Famciclovir, and valacyclovir 5-10 days |
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Term
| What agent should be used in the case of resistance to acyclovir, famicyclovir, valacyclovir, and ganciclovir |
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Definition
What agent should be used in the case of resistance to acyclovir, famicyclovir, valacyclovir, and ganciclovir
use Forcarnet by injection! |
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Term
Primary treatment of genital herpes
1st line - severe? not severe?
Other options
Relative dose in HIV?
Recurrent genital herpes?
Frequently recurring ? > 6 times/year |
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Definition
Genital Herpes
Acyclovir - IV if severe, oral if not, 10 day course for first time
Famciclovir and valacyclovir are other options.
Also acyclovir in HIV, use higher dose
Also acyclovir, famciclovir, valacyclovir for recurrent genital herpes x 5 days
> 6 times per year only valacyclovir is used, once daily dose for suppressive therapy. Use for 3-6 months |
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Term
Herpes proctitis - inflammation of rectum
DOC? |
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Definition
Herpes proctitis - inflammation of rectum
DOC - Acyclovir 10 day course |
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Term
Eczema Herpeticum - skin infections
DOC ? |
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Definition
Eczema Herpeticum - skin infections
DOC - Acyclovir, IV if severe 5-7 days |
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Term
Herpes simplex encephalitis
DOC ? course?
Recurrent course |
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Definition
Herpes simplex encephalitis
DOC - Acyclovir, 21 day course IV
Recurrent 10-14 days |
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Term
Herpes Keratoconjunctivitis
DOC ?
Other options? |
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Definition
Herpes Keratoconjunctivitis
DOC - Trifluridine (viroptic), topical drop until 7 days after re-epithelialization
Other options - Idoxuridine topical until 5-7 days AFTER resolution (should be less than 21 days total), acyclovir |
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Term
Varcilla-Zoster Virus (VZV) - Chicken pox
DOC ?
Vaccine in who? |
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Definition
Varcilla-Zoster Virus (VZV) - Chicken pox
DOC - Acyclovir
Use VZV vaccine in all susceptible > 1 year old |
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Term
Acute Herpes Zoster (shingles) With division of trigeminal nerve and duration of rash < 7 days?
With division of trigeminal nerve and duration of rash > 7 days?
Other dermatome, duration of rash greater than 72h?
Other dermatome, duration of rash less than 72h and older than 50?
Other dermatome, duration of rash less than 72h, and older than 50? |
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Definition
Acute Herpes Zoster (shingles) With division of trigeminal nerve and duration of rash < 7 days ? 7 day antivirals
With division of trigeminal nerve and duration of rash < 7 days? Analgesics, possibly neurologic analgesics or others
Other dermatome, duration of rash greater than 72h? Analgesics, possibly neurologic analgesics or others
Other dermatome, duration of rash less than 72h and older than 50? 7 day antiviral course
Other dermatome, duration of rash less than 72h, and older than 50? Analgesics, possibly neurologic analgesics or others, maybe antivirals |
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Term
Guanine nucleoside analogues (acyclovir,famciclovir, valacyclovir)
Safe in pregnancy ? |
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Definition
Guanine nucleoside analogues (acyclovir,famciclovir, valacyclovir)
Safe in pregnancy - YES! |
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Term
| How is acyclovir cleared? |
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Definition
| Renally, dose appropriately |
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