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Chapter115 - UTI
UTI
10
Medical
Professional
09/08/2011

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Cards

Term
Drug of choice for most UTIs ?

When should it not be used?
Definition
Most UTIs - SMX/TMP

Do not use it in case of sulfa allergy
Term
Empiric treatment of uncomplicated UTIs

1st line

2nd line

When should treatment Bactrim last 1 week?
Definition
Empiric treatment of uncomplicated UTIs

1st line -
SMX/TMP 3 days, TMP 3 days, or Nitrofurantoin 5 days

2nd line - FQs 7 days, cephalexin 7 days.

Bactrim treatment should last 7 days in women with symptoms lasting over a week, or recurrent UTI in last month
Term
Empiric treatment of UTIs with pyelonephritis

1st line moderate , severe
Definition
Empiric treatment of UTIs with pyelonephritis

1st line - FQs 7-14 days moderate, Aminoglycosde + if enterococcus add ampicillin.
Term
Empiric treatment of Complicated UTIs

Moderate

Severe
Definition
Empiric treatment of Complicated UTIs

Moderate: 7-10 day treatment with either SMX/TMP, FQs, Nitrofurantoin, TMP

Severe: Aminoglycosides with ampicillin if enterococcus for 10-14 days
Term
Empiric treatment of UTIs with prostatitis

Acute

Chronic
Definition
Empiric treatment of UTIs with prostatitis

Acute - Aminoglycoside with cloxacillin if S. aureus, or with ampicillin if enterococcus

Chronic - FQs 4-6 weeks!
Term
Which FQs can be used in UTIs?
Definition
CLON

Cipro, levo, oflo, nor
Term
Pregnancy w UTI - Asymptomatic bacteriuria and symptomatic cystitis

treatment?

What is teratogenic? which trimester

Preferred therapy in pyelonephritis & pregnancy?
Definition
3-7 day treatment amoxicillin, nitrofurantoin, amox/clav, cephalexin

SMX/TMP, or TMP are teratogenic 1st trimester.

Avoid FQs in pregnancy.

Preferred therapy in pyelonephritis & pregnancy is ceftriaxone
Term
Which UTI Abxs can be used in breastfeeding?
Definition
Breastfeeding - FQs, amoxicillin, nitrofurantoin, amoxicillin, and cephalosporins, SMX/TMP

NOT aminoglycosides.
Term
Prevention of UTIs in pregnant women preferred agents
Definition
Preferred agents - Nitrofurantoin or cephalexin
Term
UTIs

Contraindications in SMX ?

Contraindication in Nitrofurantoin?
Definition
SMX - sulfa allergy

Nitrofurantoin - CrCl < 60, OR pyenonephritis
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