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Chapter 9 end and Beginning of 10
Chapter 9 end and Beginning of 10
45
Microbiology
Undergraduate 1
03/09/2013

Additional Microbiology Flashcards

 


 

Cards

Term
What is Eukaryotic Transcription starting Codon?
Definition
Starting Codon on for Eukaryotic cells is AUG
Term
What is Eukaryotic translation?
Definition
It's Code for a defferent form of Methionine
Term
Eukaryotic mRNA codoes for how many proteins?
Definition
One
Term
The presence of the DNA in the nucleus means that eukaryotic transcription amd translation (can/cannot) be simultaneous?
Definition
Cannot
Term
mRNA eukaruptes must pass through ___1____ and be carried to ___2____ in the cytoplasm for translation.
Definition
1) Pores of the Nuclear memebrane
2) Ribosomes
Term
Eukaryotic genes often have ___1___,
which must be removed before translation
Definition
1)Inrons
Term
What is a Intron?
Definition
Sequences of bases that do not code for protein
Term
What are Exons?
Definition
Coding regions that will be translated into proteins
Term
What is split gene?
Definition
Requires further processing before translation.
Term
Do all introns code for all cell substances?
Definition
Yes
Term
What do genetics of animal viruses have?
Definition
They are Diverse.
Nucleic acid is linear in most viruses, but can be segmented in to several pieces.
Term
In most genetic animals viruses contain what?
Definition
dsDNA or ssRNA, but other patterns exist.
Term
In all Case of Genetics of animals viruses can have?
Definition
-Viral nucleic acid penetrantes the cell
-The nucleic acid is introduced on the the host's gene-processing machinery
-The Virus instructs the host's machinery to synthesize large numbers of new virus particles
-Viral mRNA is translated in to viral proteins on host cell ribosomes using host tRNA
Term
Genetic Regulation of protein synthesis and metabolism when?
Definition
Control mechanisms ensure that genes are ACTIVE only when their products are required.
Term
Prokaryotes organize collections of genes into?
Definition
operons
Term
What is Inducible?
Definition
The operoin is TURN ON by substrate of the enzymes for which the structural genes code (positive feedback)
Term
What is Repressible?
Definition
Contain genes coding for anabolic enzymes; several genes in a series are TURNED OFF by the product synthesized by the enzyme (negative feedback)
Term
Normally the operon is in the __1__ mode and will be turned __2__ only when the substrate is present.
Definition
1) Off
2) On
Term
The operom is kept off bu the presence of what?
Definition
Repressor
Term
When the substrate is present, it acts as an __1__?
Definition
Inducer
Term
What does the Inducer substrate do?
What is a Example?
Definition
Blocks the action of the reperssor, allowing the operon to be "on".
- Lac operon
Term
What is the an example of a lactose metabolism holder?
Definition
E. Coli
Term
What is the regulator in the lactose operon?
Definition
A gene that codes for a protein capable of repressing the operon
Term
What is the repressor in the lactose operon?
Definition
Repressing the operon.
Term
What controls the locus?
Definition
Promotor & operator
Term
What is the Promoter?
Definition
Recognized by RNA polymerase
Term
What is the Operator?
Definition
A sequence that acts as an off/on switch for transcription.
Term
Structural Locus?
Definition
Three genes each coding for a different enzyme needed to catabolize lactose.
Term
What is a repressible operon?
Example?
Definition
Normally the operon is in the "on" mode and will be turned "off" only when the nutrients is no longer reguired.
Arg operon
Term
What is Co-repressor?
Definition
The excess nutrients serves.
Needed to block the actin of the operon.
Term
There are more organism that contain genes in their (genotype/phenotype) then are manifested as a (genotype/phenotype) at a give time.
Definition
Genotype
Phenotype
Term
Example of phase variation?
Definition
Neisseria gonorrohoeae fimbrae production
Streptococcus pneumoniae capusule prodution.
Term
What is a Mutation?
Definition
A change in nucleotide sequence
Term
What is Wild type?
Definition
A miroogranism that exhibits a natural, non-mutated characteristic
Term
What is a Mutant strain?
Definition
When a miroorganism bears a mutation
Term
What is a Spontaneous mutation?
Definition
Random change in the DNA arising from errors in replication.
Term
What is Induced Mutation?
Definition
Results from exposure to known mutagens
Term
What is Point mutations?
Definition
Involve addition, deletion, or substitution of single bases
Term
What is Missense mutation
Definition
Result in different amino acid
Term
What is a Nonsense Mutation?
Definition
Results in premature stop codon
Term
What is Silent Mutation?
Definition
No effect
Term
What is a Back-Mutation?
Definition
Second mutation corrects effect of first mutation
Term
What is Frameshift mutations?
Definition
When one of more bases are inserted into or deleted from a newly synthesized DNA strand.
- Changes the reading frame of the mRNA
- Nearly always result in a nonfictional protein
Term
Positive and Negative effects of Mutations?
Definition
- Mutation are permanentWhat and inheritable
- Most are harmful but some provide adaptive advantages
Term
What type of mutation is this?
ATG(Met) -> ATC (lle)

A. Missense
B. Nonsense
C. Silent
Definition
A. Missense Because it results in different amino acids.
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