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Chapter 9
DNA structure and replication
25
Biology
Kindergarten
01/14/2013

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Term
ribose
Definition
5-carbon sugar, found in RNA
Term
deoxyribose
Definition
similar to ribose, found in DNA
Term
adenine
Definition
DNA base; equal amounts as thymine
Term
thymine
Definition
DNA base, equal amounts as adenine
Term
guanine
Definition
DNA base, equal amounts as cytosine
Term
cytosine
Definition
DNA base, equal amounts as guanine
Term
gene
Definition
section of a DNA molecule whose sequence of building blocks (4 bases) specifies the sequence of amino acids in a particular protein
Term
nucleotide
Definition
A single building block of DNA (adenine, thymine, guanine, cytosine)
Term
purines
Definition
two-ring structure; adenine and guanine
Term
pyrimidines
Definition
single-ring structure; thymine and cytosine
Term
sugar-phosphate backbone
Definition
chains that form when nucleotides form chemical bonds between the deoxyribose sugars and phosphates
Term
antiparallelism
Definition
the opposing orientation of the two nucleotide chains in a DNA molecule
Term
complementary base pairs
Definition
specific purine-pyrimidine couples ( A with T, G with C )
Term
histones
Definition
proteins around which DNA coils to form a beads on a string like structure
Term
nucleosome
Definition
one "bead" of tightly wrapped DNA on a chromosome
Term
chromatin
Definition
the totality of the chromosome substance - 30% histone proteins, 30% DNA binding proteins, 30% DNA, 10% RNA
Term
semiconservative
Definition
manner in which DNA replicates; the double helix separates and each half creates another double helix to form two from one.
Term
replication fork
Definition
a site where DNA is locally opened; resembles a fork
Term
DNA polymerase (DNAP)
Definition
an enzyme that builds a polymer (which is a chain of building blocks) and is the major replication enzyme in addition to the RNA primer
Term
ligase
Definition
enzyme that seals the sugar-phosphate backbone of the bonded building blocks, making a DNA strand
Term
primase
Definition
directs synthesis of a short RNA primer, which initiates replication
Term
helicase
Definition
enzymes that unwind and hold apart the replicating DNA
Term
annealing helicase
Definition
rewinds any sections of DNA that remain unwound at the end of the process
Term
FACT:
Definition
Some of the DNA sequence encodes protein, but most does not.
Term
ANOTHER FACT:
Definition
DNA is synthesized in a 5' to 3' direction, discontinuously on one strand
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