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Chapter 8
Human Biology
28
Biology
Undergraduate 1
10/10/2012

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Term
Protein
Definition

macromolecule

made up of repeating subunits known as amino acids 

Term
Antithrombin Protein
Definition

anti- clot

*helps prevent blood clots 

Term
Amino Acids
Definition

building blocks of proteins 

20 different types 

Term
Chromosomes 
Definition

consist of many genes

 

Term
Genes 
Definition
hold instructions to make certain proteins
Term
Gene Expression
Definition
take information in DNA and make proteins 
Term
Why are cells different? 
Definition
all cells have exactly the same genetic composition, but depending on the type of cell different GENES are expressed.
Term
Genotype 
Definition
genetic make- up based on DNA
Term
Phenotype 
Definition
physical attributes of organisms- based on expression of DNA and the environment.
Term
Thrombosis 
Definition

*autosomal recessive trait

blood clots when/ where it shouldn't

Term
Regulatory Sequence 
Definition
1st part of gene: when and how much protein a gene makes 
Term
Allele 
Definition
alternative version of the same gene that has different nucleotide sequences
Term
Coding Sequence 
Definition
determines the amino acid sequence of the encoded protein
Term
recessive
Definition
need 2 copies of the same allele in order to be expressed 
Term
dominant
Definition
only need 1 copy of the same allele in order to be expressed 
Term
Gene Therapy
Definition
cure disease by replacing defective genes with functional ones
Term
Transgenic Organism
Definition
produce massive amounts of the drug in a relatively short period of time
Term
step two of making a transgenic organism
Definition

insert desired gene (antithrombin making) into nucleus 

-offspring is a clone

Term
step three of making a transgenic organism
Definition
isolate the desired protein
Term
transcription occurs in the:
Definition
nucleus
Term
translation occurs in the:
Definition
cytoplasm
Term
transcription
Definition

-copies the coding sequence of DNA into mRNA 

-polymerase causes RNA to absorb info from DNA to create a chain of amino acids 

-makes single stranded DNA

Term
uracil
Definition
replaces thymine in RNA
Term
translation
Definition

-mRNA combines with ribosomes 

-codon specifies a specific amino acid 

-amino acids are added and the strand folds up into  3-D shape (protein)

Term
mRNA 
Definition
messenger RNA
Term
tRNA
Definition

transfer RNA 

-brings appropriate amino acid to mRNA

Term
codon
Definition
3 nucleotides
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