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Chapter 8 Bio Test
Cell Cycle
27
Biology
9th Grade
01/28/2009

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Term
Chromosomes become visable when ________
Definition
the nuclear membrane breaks down
Term
Sorting and distributing chromosomes is _____
Definition
mitosis
Term
period between divisions of cell
Definition
interphase
Term
Parts of Interphase
Definition
G1, G0, G2, S
Term
Most Adult cells are in which stage
Definition
G0
Term
G1 and G2 are the ____ stages
Definition
prepping and preparing
Term
What happens in Synthesis
Definition
each 23 sets of chromosomes creates another identical set
Term
division of a whole cell is called ______
Definition
cytokinesis
Term
Nitrogen bases and # of hydrogen bonds between them
Definition
adenine-thymine 2
guanine-cytosine 3
Term
other components of chromosomes besides nitrogen bases
Definition
deoxyribose sugar, phosphate
Term
3 steps of Synthesis
Definition
Binding of enzymes to existing DNA
Unwinding the double helix
synthesis of a new matching strand for each old one
Term
Place where enzymes bind to chromosomes
Definition
replication origins
Term
combination of DNA and proteins is called a ________
Definition
replisome (unwinds DNA)
Term
DNA repels itself because____
Definition
it has a negative charge
Term
What keeps the DNA from getting tangled and helps it fit in the nucleus? How?
Definition
Nucleosomes (made up of histones) has a slightly positive charge and the DNA wraps itself around it
Term
Nucleosomes combined with DNA is called____
Definition
chromatin
Term
mutagenic is ____
Definition
an environmental factor that mutates cells
Term
process of repairing mutated cells
Definition
excision repair
Term
sister chromotids are connected at the ______
Definition
centromere
Term
seperation of sister chromotids is called _______
Definition
chrmosome segregation
Term
daughter cells with abnormal number of chromosomes are called ______
Definition
aneuploid cells
Term
stages of mitosis
Definition
prophase- nuclear envelope breaks down, chromosmes condense, microtubules go around nucleus and form mitotic spinle and then attatch to proteins and form spindle poles, microtubules bind to kinetochore,
metaphase- chromosomes are in ring between two poles and form mitaphase plate
anaphase- enzymes break down centromere, sister chromotids seperate to spindle poles
telophase- necluer envelope re-froms around the chromosomes, forming 2 cells
Term
protein complex in centromere is called _____
Definition
kinetochore
Term
cyclins are highest when and activate what? What are the two types?
Definition
G1 cyclins peak in S phase, mitotic cyclins peak in metaphase. they activate kinases
Term
process of tumor spreading through body
Definition
metastasis
Term
2 signals cancerous cells ignore
Definition
proto-oncogenes (regulare cell cycle) and tumor surpressors (checkpoints)
Term
when cell is halted it is in _______
Definition
cell cycle arrest
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