Term
|
Definition
-floxacin
Rx: Gram negative infections
Mech: Inhibits Type II topoisomerases
Bactericidal
Cartilage damage and tendon rupture |
|
|
Term
|
Definition
Quinolone
CAN'T BE USED WITH TIZANDINE ADMINISTRATION |
|
|
Term
|
Definition
Rx: Mycobacterium
DO NOT USE WITH Neisseria meningitidis
DO NOT GIVE WITH CLARITHROMYCIN |
|
|
Term
|
Definition
Rx: Meningococcal disease and Mycobacterium
DO NOT USE WITH Neisseria meningitides
MAY REDUCE CYCLOSPORINE CONCENTRATION |
|
|
Term
|
Definition
-mycin, -micin, -kacin
Rx: Serious Gram-negative infections
Mech: Binds to 16S rRNA
AE: Ototoxicity, acute renal failure, and neuromuscular blockade
Bactericidal |
|
|
Term
|
Definition
| Act synergistically with B-lactams |
|
|
Term
|
Definition
Aminoglycoside
Rx: Alternative treatment for Gonorrhea
Mech: Permits formation of 70S complex
Bacteriostatic |
|
|
Term
|
Definition
-cycline
Rx: Corynebacterium acnes, Haemophilus influenza, Vibrio cholera, spirochetes, Mycoplasma pneumoniae, Chlamydia species, and rickettsial species (GRAM (-) AND GRAM (+))
CI: Last half of pregnancy, Infancy, and Childhood up to 8 yrs |
|
|
Term
|
Definition
Binds to 16S rRNA
Rx: Malaria prophylaxis |
|
|
Term
|
Definition
Rx: Broad spectrum, Skin infections, Abdominal infections, and Community-Acquired pneumonia
AE: GI disturbances |
|
|
Term
|
Definition
-thromycin
Drugs: C.A.T.E.
Mech: 23S rRNA
ALL DRUGS ARE BACTERIOSTATIC
AE: Acute cholestatic hepatitis and ototoxicity |
|
|
Term
|
Definition
| Rx: Corynebacterium acnes, Legionella pneumophila, Treponema pallidum, Mycoplasma pneumoniae, and Chlamydia |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Rx: H. influenza and Moraxella catarrhalis |
|
|
Term
|
Definition
Macolide
AE: Fulminant hepatic necrosis |
|
|
Term
|
Definition
Mech: Binds to the 23S rRNA
Rx: Broad-spectrum (especially anaerobes) and rickettsiae
AE: GRAY BABY SYNDROME
DO NOT USE WITH PENICILLINS OR AMINOGLYCOSIDES
INHIBITS MITOCHONDRIAL FUNCTION
Bacteriostatic |
|
|
Term
|
Definition
Mech: 23S rRNA inhibitors
Rx: Anaerobic organisms
AE: Pseudomembranous colitis and jaundice
Bacteriostatic |
|
|
Term
|
Definition
Streptogramins
Mech: 23S rRNA inhibitors
Rx: Vancomycin resistant Enterococcus faecium (VREF), Skin infections caused by S. aureus and S. pyogenes |
|
|
Term
|
Definition
Mech: Binds to 23S rRNA (exact mech is unknown)
Rx: G(+); VREF, MRSA, S. agalactiae, S. pneumoniae, and S. pyogenes
Rx: Nosocomial pneumonia and complicated diabetic foot infections
AE: Peripheral neuropathy and OPTIC NEUROPATHY |
|
|
Term
|
Definition
Mech: 23S rRNA inhibitors
Rx: Impetigo (S. pyogenes and MRSA); G(+)
TOPICAL APPLICATION |
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|
