Term
| What are some of the uses of Aspirin |
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Definition
Mild/moderate fever relief
Anticogulant activity (reduces the risk of death after MI)
Reduce incidents of strokes.
Reduces risk of colorectal cancer. |
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Term
| What are some of the adverse effects of aspirin? |
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Definition
Gastric discomfort and bleeding
Salicylism |
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Term
| Who should not be given aspirin? |
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Definition
Patients receiving anticoagulant therapy such as warfarin, heparin and plicamycin.
Also category D for pregnant women |
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Term
| What are some things to know about aspirin before you administer it? |
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Definition
Aspirin should be discontinued 1 week before surgery (anticoagulant)
Aspirin is excreted in the urine and affects urine testing for glucose and other metabolites |
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Term
| Aspirin would increase the risk of bleeding if given with |
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Definition
| Feverfew, garlic, ginger, and ginkgo |
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Term
| What type of drug is aspirin? |
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Definition
| COX inhibitor; NSAID, antipyretic |
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Term
| What type of drug is ibuprofen? |
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Definition
| Anti-inflammatory, analgesic, antipyretic (NSAID) |
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Term
| What is Ibuprofen prescribed for? |
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Definition
| Mild-moderate pain, fever and inflammation |
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Term
| Administration alerts for ibuprofen? |
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Definition
Give drug on an empty stomach as tolerated*
If pt has allergy to aspirin, could exhibit hypersensitivity reaction to ibuprofen
Pregnancy category B |
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Term
| What are some drug-drug interactions of ibuprofen |
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Definition
Should not be taken with anticoagulants
Can cause lithium toxicity
May lessen effects of diuretics
Use with other NSAIDs, alcohol or corticosteroids may cause serious adverse GI effects |
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Term
| Do not use Ibuprofen with |
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Definition
**Pt for perioperative pain in the setting of coronary artery bypass graft surgery!!!
PT with renal/hepatic impairment |
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Term
| What teachings should patients receiving NSAID therapy receive? |
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Definition
Teach PT to supplement drug therapy with nonpharmacologic measures
Teach PT to abstain from alcohol while taking acetaminophen
Teach PT to IMMEDIATELY report any signs of GI bleeding
Teach PT to IMMEDIATELY report any sign/symptoms of ringing, humming, buzzing in ears, difficulty with balance, dizziness or vertigo or nausea. |
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Term
| Adverse effects of ibuprofen |
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Definition
Nausea, heartburn, epigastric pain.
GI ulceration with high doses
Renal impairment with chronic use |
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Term
| When administering NSAIDs, the nurse should |
|
Definition
Obtain baseline kidney/liver funtion (CBC)
Monitor bleeding time with long term administration
Assess for changes in pain, reduction in temperature and inflammation
Assess for GI bleeding, hepatitis, nephrotoxicity, hemolytic anemia and salicylate toxicity
Use catiously in ederly
Contraindicated in pediatric pts |
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Term
| Prototype for glucocorticoids |
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Definition
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Term
| Glucocorticoids has what contraindications?? |
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Definition
| Patients with active viral, bacterial, fungal, or protozoan infections should not take prednisone. |
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Term
| Adverse effects of glucocorticoids |
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Definition
| Long term use of glucocorticoids results in Cushing's Syndrome (hyperglycemia, fat distribution to shoulders/face, muscle weakness, bruising and bones that fracture easily. |
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Term
| Serious adverse effects of glucocorticoids |
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Definition
hyperglycemia
mood changes, peptic ulcers, cataracts
electrolye imbalances
**Can Mask Infections |
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Term
| What are the most common adverse effects of penicillin |
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Definition
| nausea, vomiting, diarrhea -- most complications in children + older adults |
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Term
| Penicillin is contraindicated in patients with |
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Definition
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Term
| Interactions with penicillin G |
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Definition
decreases effectiveness of oral contraceptives
colestipol decreases absorption of penicillin
potassium-sparing diuretics can cause hyperkalemia when given with penicillin |
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Term
| Penicillin is normally administer by |
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Definition
IM or IV,
oral administration is only absorbs 15%-30%. |
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Term
| What is the pharmacologic and therapeutic class of penicillin G |
|
Definition
Therapeutic: Antibacterial
Pharmcologic: Cell Wall Inhibitor |
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Term
| What would penicillin lab tests look like? |
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Definition
| May give false coombs test and false positive urinary or serum proteins |
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Term
| What is the therapeutic class and pharmacologic class of Claforan |
|
Definition
Therapeutic Class: Antibacterial
Pharmacologic Class: Cell wall inhibitor |
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Term
| What is the most common adverse effect of claforan |
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Definition
Hypersensitivity
So the drug should be used with caution in patients with severe renal disease |
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Term
| What are some drug-drug interactions of claforan |
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Definition
| Probenecid -> may cause cephalosporin toxicity |
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Term
| How do you administer claforan |
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Definition
| Adminiter IM injections deep into large muscle mass to prevent injury to surrounding tissues. |
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