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Chapter 31
The Amygdala, The Basal Forebrain, & Emotions
47
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Undergraduate 3
12/01/2015

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Term
2 parts of the neocortex that are strongly implicated in processing of emotions
Definition
1. prefrontal cortex
2. insula
Term
basal forebrain
Definition
cell groups in the basal parts of the hemispheres that are densely interconnected with both limbic structures & the neocortex; participates in both emotional & cognitive processing
Term
2 nuclear groups of the amygdala
Definition
1. small corticomedial (central nucleus)
2. large basolateral (lateral nucleus)
Term
What is the central task of the amygdala?
Definition
the establishment of links between stimuli & their emotional value
Term
How does damage to the amygdala affect social interactions?
Definition
it leads to difficulties in social interactions
Term
4 places where the corticomedial nuclei of the amygdala receive afferents from
Definition
1. olfactory bulb
2. hypothalamus
3. intralaminar thalamic nuclei
4. septal nuclei
Term
What type of fibers does the corticomedial nuclei of the amygdala receive from the ventral tegmental area in the mesencephalon?
Definition
dopaminergic
Term
What is the path of ascending fibers of spinal lamina I nociceptive neurons to the amygdala?
Definition
end in parts of the parabrachial area that project to the central amygdaloid nucleus
Term
What type of information does the lamina I-parabrachial-amygdaloid pathway contribute to?
Definition
the emotional aspects of pain
Term
4 places where the basolateral nuclei of the amygdala receives afferents from
Definition
1. thalamic nuclei
2. prefrontal cortex
3. temporal lobe
4. cingulate gyrus
Term
Do the basolateral nuclei (lateral nucleus) of the amygdala receive one type or many types of sensory information?
Definition
many types
Term
Does the amygdala receive information about fear-provoking stimuli & their context?
Definition
yes!
Term
Is there a major efferent pathway from the amygdala to the hypothalamus?
Definition
yes!
Term
stria terminalis
Definition
collections of the efferent fibers from the amygdala to the hypothalamus that are visible macroscopically & arch over the thalamus
Term
What do effernts from the amygdala to the thalamus allow for?
Definition
they enable signals from the amygdala to reach the prefrontal cortex
Term
2 places where the basolateral nuclei of the amygdala send efferents
Definition
1. ventral striatum
2. basal nucleus
Term
How do projections from the amygdala to the basal nucleus show up on an EEG?
Definition
they show up as an activation of the EEG
Term
How does the amygdala impact learning?
Definition
we remember better the material that has an emotional coloring
Term
3 brain stem nuclei that receive efferents from the amygdala
Definition
1. PAG
2. reticular formation
3. parasympathetic cranial nerve nuclei
Term
What are connections between the amygdala & PAG involved in?
Definition
eliciting conditioned fear behavior
Term
4 movements elicited by stimulation of the corticomedial nuclear group of the amygdala
Definition
1. smacking
2. salivation
3. licking
4. chewing
Term
3 movements elicited by stimulation of the basolateral nuclear group of the amygdala
Definition
1. lifting head
2. pupils are dilated
3. looking around
Term
Does the sight of faces expressing anger or fear cause an activation or a deactivation of the amygdala as shown via fMRI?
Definition
activation
Term
How do amygdaloid lesions affect the ability to recognize facial expressions?
Definition
they lead to difficulty with recognizing facial expressions
Term
How does the amygdala work as a sort of alarm?
Definition
it evaluates very rapidly a stimulus for its threatening value & initiates appropriate behavior
Term
Is the amygdala necessary for expression of emotions?
Definition
yes!
Term
What are connections between the basolateral amygdala & the ventral striatum necessary for?
Definition
establishing stimulus-reward associations
Term
What are connections from medial parts of the prefrontal cortex with the amygdala necessary for?
Definition
unlearning (extinction) of the conditioned fear response
Term
How does the prefrontal cortex act on the amygdala during extinction?
Definition
it inhibits the amygdala; the synaptic changes underlying the associations do not disappear
Term
What is the cingulate gyrus involved in?
Definition
organization & initiation of various kinds of goal-directed behavior
Term
Does stimulation of the motor cortex produce vasomotor changes in the ipsilateral or contralateral body half?
Definition
contralateral
Term
What does stimulation of the frontal eye field produce?
Definition
pupillary dilation
Term
What is the difference between the roles of the rostral part of the anterior cingulate cortex (ACC) (the anterior part of the cingulate gyrus) & the caudal part?
Definition
rostral = affect regulation

caudal = cognitive task
Term
What is the ACC of the cingulate gyrus important for?
Definition
the choice of behavior in response to conflicting stimuli
Term
What do parts of the cingulate gyrus & the anterior insula work together to do?
Definition
alter activity in relation to emotions such as admiration & compassion
Term
What are the orbitofrontal & ventromedial parts of the prefrontal cortex important for?
Definition
emotional regulation
Term
What is the orbitofrontal cortex important for?
Definition
behavioral flexibility (the ability to alter behavior when needed & to choose among conflicting choices)
Term
5 brain parts that monitor the energetic demands involved in performing a task
Definition
1. amygdala
2. nucleus accumbens
3. orbitofrontal cortex
4. insula
5. ACC
Term
What is another name for the basal forebrain?
Definition
substantia innominata
Term
3 overlapping regions of the basal forebrain
Definition
1. ventral striatopallidum
2. extended amygdala
3. basal nucleus
Term
Where are ACh neurons of the basal forebrain found?
Definition
in a thin disc close to the basal surface of the hemisphere (basal nucleus) & in the septal nuclei & the diagonal band of Broca that extend dorsally close to the midline
Term
Between what 2 structures does the diagonal band of Broca form a transition?
Definition
the basal nucleus & the septal nuclei
Term
2 places where the basal forebrain gets ACh afferents from
Definition
1. locus coeruleus
2. ACh cell groups in the dorsolateral pons
Term
3 places where the basal forebrain gets afferents from
Definition
1. hypothalamus
2. cingulate gyrus
3. nucleus accumbens of the ventral striatum
Term
3 things the septal nuclei influence
Definition
1. autonomic functions
2. emotions
3. behavioral reactions
Term
2 things the ACh neurons in the basal forebrain are important for
Definition
1. attention
2. memory
Term
Where do patients with Alzheimer's disease have a lot of cell loss?
Definition
in the basal nucleus
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