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Chapter 2: Chemical Level of Organization
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86
Physiology
Undergraduate 1
05/16/2013

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Term
atomic number
Definition
total protons
Term
mass number
Definition
protons + neutrons
Term
isotopes
Definition
same #protons, different # neutrons
Term
atomic weight
Definition
actual mass of an atom, expressed in daltons (da). Usually an average of the naturally occurring isotopes
Term
% of TBA: O
Definition
65
Term
% of TBA: C
Definition
18.6
Term
% of TBA: H
Definition
9.7
Term
% of TBA: N
Definition
3.2
Term
% of TBA: Ca
Definition
1.8
Term
% of TBA: P
Definition
1
Term
% of TBA: K
Definition
0.4
Term
% of TBA: Na
Definition
0.2
Term
% of TBA: Cl
Definition
0.2
Term
single covalent bond
Definition
one pair of electrons shared between atoms
Term
double covalent bond
Definition
two pairs of electrons are shared between atoms
Term
polar covalent bond
Definition
covalent bond that creates a polar molecule
Term
reactants
Definition
atoms or molecules present before chemical reaction
Term
products
Definition
atoms or molecules present after a chemical reaction
Term
metabolism
Definition
sum of all reactions occurring in the body at a given moment.
Term
work
Definition
the movement of an object or change in physical structure of matter
Term
energy
Definition
the capacity to perform work
Term
kinetic energy
Definition
movement energy - can be transferred to another object to perform work
Term
potential energy
Definition
stored energy - has the potential to to do work, if released. E.g., object sitting on edge of table, charged battery.
Term
mole
Definition
quantity with a weight in grams equal to an element's atomic weight. E.g., the atomic weight of oxygen is 16, so 1 mole of oxygen weighs 16 g.
Term
molecular weight
Definition
sum of the atomic weights of all its components
Term
chemical decomposition
Definition
AB -> A+B
Term
hydrolysis
Definition
A form of decomposition involving water:
AB+H2O -> A-H + B-OH
Term
catabolism
Definition
the collective decomposition reactions in the body. Covalent bonds are a form of stored energy, so when they are broken down, energy is released.
Term
chemical synthesis
Definition
A+B -> AB
Term
dehydration synthesis
Definition
A-H + B-OH -> AB + H20
Term
anabolism
Definition
the sum of all synthesis reactions in the body. Creating covalent bonds costs energy, so the body must find an equilibrium between catabolic and anabolic reactions, using the former to feed the energy needs of the latter.
Term
exchange reaction
Definition
AB+CD -> AC + BD
Term
activation energy
Definition
the amount of energy required to start a reaction
Term
catalyst
Definition
compound that accelerates chemical reactions without being consumed itself
Term
enzyme
Definition
promote chemical reactions by lowering the activation energy requirements. enzymes are generally proteins.
Term
metabolic pathway
Definition
A series of interlocking steps in which a molecule is manipulated into a final product by a sequence of enzymes.
Term
exergonic
Definition
Chemical reaction that releases more energy than it takes.
Term
endergonic
Definition
Chemical reactions that require more energy than they produce.
Term
metabolites
Definition
All the molecules that cam be synthesized or broken down by chemical reactions inside our bodies.
Term
nutrients
Definition
essential metabolites that are normally obtained from the diet.
Term
organic compounds
Definition
always contain carbon and hydrogen as their primary structural ingredients. E.g. sugars, fats, proteins, nucleic acids.
Term
Inorganic compounds
Definition
generally do not contain carbon and hydrogen as their primary structural ingredients. E.g. CO2, H2O, O2, acids
Term
Thermal inertia
Definition
The tendency of a large mass of water to change temperature slowly.
Term
Solution
Definition
A mixture of two or more substances.
Term
Solvent
Definition
The medium in which solutes are dissolved.
Term
Solute
Definition
The atoms, ions, or molecules which are dissolved in the solution.
Term
Dissolve
Definition
The breaking down of crystalline compounds into individual molecules within a solvent, or volume of another chemical. In the body, the solvent is usually water, and solutes include ions and sugars.
Term
Ionization
Definition
(dissociation) - the breaking of ionic bonds of compounds within an aqueous solution. Produces ions.
Term
Hydration sphere
Definition
The sheath of water molecules surrounding an ion in an aqueous solution.
Term
Hydrophilic
Definition
Molecules that readily interact with water molecules in solution.
Term
NaCl ->
Definition
Na+ + Cl-
Term
KCl ->
Definition
K+ + Cl-
Term
CaPO4 (Calcium Phosphate) ->
Definition
Ca++ and PO4-- (phosphate)
Term
NaHCO3 (Sodium bicarbonate) ->
Definition
Na+ and HCO3- (bicarbonate)
Term
MgCl2 (Magnesium Chloride) ->
Definition
Mg++ and 2Cl-
Term
Na2HPO4 (sodium hydrogen phosphate) ->
Definition
2Na+ and HPO4-- (hydrogen phosphate)
Term
Na2SO4 (Sodium sulfate)
Definition
2Na+ and SO4-- (sulphate)
Term
Colloid
Definition
A solution with dispersed large particles, such as proteins or starches. These molecules will remain dissolved indefinitely.
Term
Suspension
Definition
Solution with very large particles that will settle out if left undisturbed (e.g. blood,lipids in water).
Term
Hydrogen ion
Definition
A proton; the principle molecule of acidity.
Term
carboxylic acid group
Definition

[image]

Fatty acids, amino acids

Term
Amino group
Definition

[image]

Amino acids

Term
Hydroxyl group
Definition
[image]
Term
Phosphate group
Definition
[image]
Term
isomers
Definition
Same molecular formula, but different structures. E.g. glucose and fructose.
Term
common monosaccharides
Definition
glucose, fructose
Term
common disaccharides
Definition
sucrose (table sugar), lactose, maltose
Term
polysaccharides
Definition
glycogen, starch
Term
ratio of C:H:O in carbohydrates
Definition
1:2:1
Term
ratio of C:H in lipids
Definition
1:2
Term
compare saturated and unsaturated fatty acids
Definition
saturated: each carbon has four single covalent bonds (2 H per C)
unsaturated: one or more double bonds between C's, thus some C's only bond to 1 H.
Term
Eicosanoids: Key structural aspects and types.
Definition
Lipids derived from arachidonic acid (an essential fatty acid). Leukotrienes and prostaglandins are eicosanoids.
Term
Steroids: Key structural aspects and types.
Definition
Steroids have a carbon-ring framework. Cholesterol and the sex hormones are examples.
Term
Phospholipid: structure and examples
Definition
Diglyceride tail, connected to a phosphate group, then a nonlipid group. Used in cell membrane.
Term
Glycolipid: structure and example
Definition
Diglyceride tail, connected to a carbohydrate. Utilized in the cell membrane for cell recognition and for recognition of substances outside the cell.
Term
micelle
Definition
Glycolipid/phosopholipid droplet formed in water, in which the tails are oriented inward, and the heads outward. Micellles form during digestion.
Term
What 2 components do each amino acid contain.
Definition
An amino group, and a carboxylic group.
Term
Explain primary protein structure.
Definition
The sequence of amino acids in the protein
Term
Explain secondary protein structure.
Definition
Folding of proteins into either Alpha-helix or pleated sheets.
Term
Explain tertiary protein structure.
Definition
Complex coiling of of the protein into a 3D shape. Results from interactions between the polypeptide chain and surrounding water molecules.
Term
Explain quaternary structure.
Definition
Further folding of the protein. Results from the interaction between individual polypeptide chains.
Term
substrates
Definition
reactants in an enzymatic reaction.
Term
How are enzymes turned on or off?
Definition
Changes to the tertiary or quaternary shape.
Term
Saturation limit
Definition
The substrate concentration required to have the maximum rate of reaction.
Term
What are the components of AMP/ADP/ATP.
Definition
Adenine, connected to ribose, connected to 1-3 phosphate groups.
Term
Name the components and structure of DNA
Definition
deoxiribose sugar
nitrogenous base: adenine, thymine, guanine, cytosine
phosphate group
in a double helix
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