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Chapter 29
Sensory Visceral Neurons & Visceral Reflexes
39
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Undergraduate 3
11/08/2015

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Term
mechanoreceptors
Definition
record the tension of the tissue in which they are located; make up a large group of the visceral receptors
Term
Are sensations of pain mostly from stretch receptors that give rise to sensations of pain by responding to strong dilation of a hollow organ & to forceful contractions of the smooth musculature or from chemoreceptors sensitive to substances in the tissue produced by inflammation or ischemia?
Definition
chemoreceptors sensitive to substances in the tissue produced by inflammation or ischemia
Term
What do chemoreceptors in the vascular system react to?
Definition
carbon dioxide & oxygen concentration in the blood
Term
Do visceral receptors typically have large or small receptive fields?
Definition
large receptive fields with a low density of nerve endings
Term
What does it mean that visceral receptors exhibit marked "spatial summation"?
Definition
the threshold for eliciting action potentials becomes lower as the area of stimulation increases
Term
4 places where visceral afferents leading from nociceptors do NOT follow the sympathetic nerves
Definition
1. neck of the bladder
2. prostate
3. cervix uteri
4. rectum
Term
What do "pain fibers" from the bladder/prostate/cervix uteri/rectum follow?
Definition
parasympathetic pelvic nerves to the sacral spinal nerves
Term
What do fibers carrying nociceptive signals from the arteries in the extremities & the body wall follow?
Definition
the spinal nerves together with the sympathetic efferent fibers
Term
Where do the sensory signals from the visceral organs primarily end after passing through the dorsal roots?
Definition
the dorsalmost parts of the dorsal horn (lamina 1)
Term
Where do the sensory fibers following the cranial nerves end?
Definition
the solitary nucleus in the medulla
Term
What produces the visceral reflexes of coughing & respiratory adjustments?
Definition
stimulation of receptors in the lungs & the airways
Term
What reflex is caused by irritation of the mucosa of the stomach?
Definition
the vomiting reflex
Term
What stimulates the emptying reflexes of the rectum & the bladder?
Definition
stimulation of stretch receptors in their walls
Term
Signals from what kinds of receptors in the bronchial walls contribute to inhibition of inspiratory movements when the lungs have been inflated to a certain extent?
Definition
stretch receptors
Term
When is substance P released from the free nerve endings that cause the cough reflex in the lungs?
Definition
exposure to irritant gases
Term
Where is the J (juxtapulmonary) receptor located?
Definition
close to the lung alveoli
Term
What feelings do signals from the J receptors cause when these signals reach consciousness?
Definition
shortness of breath (dyspnea)
Term
What is normal adult bladder capacity?
Definition
about 500 mL
Term
Why does urine not leak out of the bladder in the filling phase?
Definition
intraurethral pressure is kept higher than intravesical pressure
Term
detrusor muscle
Definition
the smooth muscle of the bladder wall; in the filling phase, it is relaxes while the striated external sphincter in the pelvic floor is tonically active
Term
Normal emptying of the bladder requires coordinated control of what 2 kinds of neurons?
Definition
1. parasympathetic preganglionic neurons in the S3-S4 segments
2. alpha motoneurons in the S1-S3 segments
Term
What neurotransmitter is responsible for the parasympathetic control of the detrusor muscle?
Definition
ACh
Term
Where is the pontine micturition center (the neuronal network that coordinates the spinal reflexes involved in micturition) located?
Definition
the dorsolateral pons
Term
What mediates the marked emotional influence on micturition (ex. frequent urination in association with nervousness & fear)?
Definition
connections from the amygdala to the PAG
Term
In terms of urination, what is associated with damage of the pyramidal tract in the spinal cord?
Definition
urge incontinence as a sign of impaired central bladder control
Term
2 cell groups involved in the voluntary control of micturition
Definition
1. medial parts of the frontal lobe
2. medial parts of the hypothalamus
Term
In terms of urination, what is caused by damage to the frontal lobes?
Definition
urge incontinence
Term
2 muscles that must coordinate for successful expulsion of semen
Definition
1. smooth muscles closing the upper urethra
2. striated muscles of the pelvic floor (sphincter muscles & muscles around the penile cavernous bodies, esp. the bulbospongiosus muscle)
Term
2 cell groups that control the spinal reflex centers for erection & ejaculation
Definition
1. cell groups in the reticular formation of the pons (close to those controlling micturition)
2. cell groups in the hypothalamus
Term
Descending connections from what part of the brain inhibits the spinal reflex centers of erection & ejaculation?
Definition
an area in the ventral part of the upper medulla that sends descending connections that act on parasympathetic & sympathetic preganglionic neurons & alpha motoneurons
Term
Do visceral disease processes (ex. appendicitis) initially cause a vague discomfort & nausea or do they initially cause pain?
Definition
vague discomfort with nausea
Term
Is visceral pain typically accompanied by slow pulse, lowered blood pressure, & cold sweat?
Definition
yes!
Term
Are nausea/vomiting & a tendency to keep still frequent in patients with visceral pains?
Definition
yes!
Term
What part of the brain orchestrates most of the symptoms of visceral pain?
Definition
the periaqueductal gray (PAG)
Term
What causes the pain of migraine?
Definition
dilation of the extracranial arteries & subsequent inflammation
Term
Why does referred pain occur?
Definition
the diseased organ & the site of referred pain receive sensory innervation from the same spinal segments
Term
Where is the pain arising in the heart usually referred to?
Definition
the ulnar aspect of the left arm or the upper part of the chest
Term
Where is pain from the diaphragm usually referred to?
Definition
the shoulder
Term
2 areas of the skin where bladder pain is usually referred to
Definition
1. an area of the skin innervated by the spinal segments S2-S3
2. an area of the skin higher up on the back innervated by the lower thoracic & upper lumbar segments
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