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Chapter 2
Chapter 2
28
Physiology
Undergraduate 3
04/29/2010

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Term
biomolecule
Definition
Organic molecules associated with living organisms: carbohydrates, lipids, proteins and nucleotides
Term
monosaccharide
Definition
Simple sugars such as glucose 
Term
disaccharide
Definition

ugar composed of two sugar monomers

 

(COH2)2

Term
glucose
Definition

A six-carbon sugar that is a major energy source for the body. Synonym: dextrose
Term
glycogen
Definition

Storage polysaccharide found in animal cells
Term
Lipids
Definition

molecules made up of carbon hydrogen and oxygen, they are not soluble in water as they are non polar

 

There are also lipid related structures phospholipids and steroids and eicosonoids

Term
Fatty acids
Definition

long chains of carbon bound to hydrogen with an carboxyl at the end (-COOH)

 

If there is no double bond between carbon atoms it is called a saturated fatty acid

 

One double bonds in molecule = monosaturated

 

More than two double bonds in the molecule = polysaturated

Term
steroid
Definition
Lipid-related molecules derived from cholesterol structure includes 4 linked carbon molecules
Term
protein
Definition

A chain of more than one hundred amino acids
Term
amino acid
Definition
Molecule with a central carbon atom linked to a hydrogen atom, an amino group, a carboxyl group, and a variable group of atoms designated “R.” The building blocks of proteins
Term
peptide
Definition
A chain of 2-9 nine amino acids
Term
polypeptide
Definition

A chain of 10–100 amino acids
Term
peptide bond
Definition

Bond formed between carboxyl group of one amino acid and amino group of another amino acid
Term
oligiopeptide
Definition
a peptide consisting of 2-9 amino acids linked together
Term
primary structure, of protein
Definition
The sequence of amino acids in the peptide chain
Term
secondary structure, of protein
Definition

Spatial arrangement of amino acids in the chain.
Term
tertiary structure, of protein
Definition

Globular or fibrous three-dimensional shape of a protein molecule

 

Fibrous: pleated sheets or helixes

 

Globular: aminoacids that fold back on themselves creating a complex structure including knobs pockets or channels

 

Globular proteins are soluble in water, they also function as enzymes

Term
quaternary structure, of protein
Definition

Arrangement of a protein with multiple peptide chains
Term
nucleotide
Definition

A biomolecule used for storage and transfer of information and energy; composed of phosphate groups, a five-carbon sugar, and  a base
Term
specificity
Definition

The ability of an enzyme or receptor to bind to a particular molecule or a group of closely related molecules
Term
affinity
Definition
The degree to which a protein is attracted to its ligand
Term
agonist
Definition

Molecules that combine with a receptor and mimic a response
Term
cofactor
Definition
An inorganic or nonprotein organic molecule required for activation of protein
Term
antagonist
Definition
One substance opposes the action of another
Term
competitive inhibitor
Definition

Molecules that bind to the active site of the enzyme, preventing substrate binding
Term
allosteric modulator
Definition
Bind to an enzyme away from the binding site and change the shape of the active site
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