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| A chemical or drug that binds to a receptor and creates an effect on the body |
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| A chemical or drug that binds to a receptor but does not create an effect on the body; it actually blocks the receptor site from accepting the agonist |
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| Amount of drug that reaches the systemic cirrculation |
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| Method by which the drug is made available to the body |
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| Initial metabolism in the liver of a drug taken orally before the drug reaches the systemic cirrculation |
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| An allergic or immune-mediated reaction to a drug, which can be serious, requiring airway maintenance or ventilatory assistance |
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| An abnormal or unexpected reaction to a drug, other than an allergic reaction, as compared with the predicted effect |
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| Taking a substance, typically in the form of gases, fumes, vapors, mists, aerosols, or dusts, into the body by breathing in |
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| Limited to the area of treatment |
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| Lung Availability/Systemic Availability |
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| Amount of drug that is made available to the lung out of the total available to the body |
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| Any way other than the intestine most commonly an injection |
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| the mechanisms of the drug action by which the a drug molecule causes its effect in the body |
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| the study of genetic factors and their influence on drug response |
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| the time course and disposition of a drug in the body, based on its absorbing, distribution, metabolism, and elimination |
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| A cell component that combines with a drug to change or enhance the function of the cell |
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| Structure-Activity Relation (SAR) |
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Definition
| Relationship between a drug's chemical structure and the outcome it has on the body |
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| A drug interaction that occurs from combined drug effects that are greater than if the drugs were given alone |
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| Pertains to the whole body, whereas the target for the drug in not local, possibly causing side effects |
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| A rapid decrease in response to a drug |
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| Difference between the minimal therapeutic and toxic concentrations of a drug; the smaller the difference the greater chance the drug will be toxic |
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| Describes a decreasing intensity of response to a drug over time |
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| Use of the skin or mucous membrane |
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