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Chapter 22 Pharmacology
Pharmacology, Dr. T, EU
87
Biology
Undergraduate 4
11/21/2011

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Term
Schedule I Drugs
Definition

are not considered to be legitimate for medical use in the USA. They are used for research only and they cannot be perscribed, having a high risk of abuse

ex. LSD, heroin, marijuana

Term

Schedule II Drugs

 

Definition

have accepted medical use but have a high potential for abuse or addiction. These drugs must be ordered by written prescritpion and cannot be refilled without a new, written prescription.

ex. Morphine, cocaine, codeine, Demerol, Dilauded

Term
Schedule III Drugs
Definition

have moderate potential for abuse or addiction, low potential for physical dependence. These drugs may be ordered by written prescription or by telephone order. Prescription expires in six months. They may not be refilled more than five times in a six-month period.

Ex. Tylenol with codeine, Butisol, Hycodan

Term
Schedule IV Drugs
Definition
have less potential for abuse or addiction than those of Schedule III, with limited physical dependence. These drugs may be ordered by written prescription or by telephone order. They may be refilled up to five times over a six-month period. Prescription expires in six months.
Term
Schedule V Drugs
Definition
have a small potential for abuse or addiction. These drugs may be ordered by written prescription or by telephone order and there is no limit on prescription refills. Some of these drugs may not need a prescription.
Term
Adverse Reaction
Definition
The body's reaction to a drug in an unexpected way that may endanger a patient's health and safty.
Term
Anaphylactic Shock
Definition
A life-threatening, hypersensitive reaction to food or drugs. The patient experiences acute respiratory distress; hypotention; edema; tachycardia; cool, pale skin; cyanosis; and possibly convulsions shortely after administration of the medication.
Term
Bacteriostatic
Definition
Stopping or controlling the growth of bacteria.
Term
Brand Name
Definition
The name under which the drug is sold by a specific manufacturer. This name is owned by the manufacturer, and no other company may use that name. Each brand name carries a registered trademark symbol. Also known as trade name.
Term
Buccal Medication
Definition
Medication placed in the mouth next to the cheek, where it is absorbed into the mucous membrane lining of the mouth.
Term
Chemical Name
Definition
The chemical name for a drug is the description of the chemical structure of the drug. It is listed in the Hospital Formulary along with the chemical formula diagram.
Term
Chemotherapy
Definition
The treatment of diseases by using drugs that have a specific deadly effect on disease-causing microorganisms. These drugs are used in the treatment of certain infections and cancer.
Term
Contraindication
Definition
Any special symptom or circumstance that indicates that the use of a particular drug or procedure is dangerous, not advised, or has not been proven safe for administration.
Term
Controlled Substances
Definition

Drugs that have a potential for abuse. These drugs are placed into five categroes, ranging from Schedule I drugs to Schedule V drugs, which are the least dangeous and least likely to be abused;

also known as schedule drugs.

Term
Controlled Substances Act
Definition
The federal law concerned with the manufacture, distribution, and dispensing of controlled substances. These drugs have the potential of being abused and of causing physical or psychological dependence.
Term
Cumulation
Definition
menas that a drug level begins to accumulate in the body with repeated doses because the drug is not completely excreted from the body before another dose is administered.
Term
Desired Effect
Definition
The effect that was intended; that is, if the drug lowered the blood pressure as was intended, the desired effect was achieved.
Term
Drug
Definition
Any substance that when taken into the body may modify one or more of its functions.
Term
Drug Action
Definition
Describes how a drug produces changes wtihin the body
Term
Drug Effect
Definition
describes the change that takes place in the body as a result of the drug action
Term
Drug Enforcement Administration
Definition
The government agency responsible for administering and enforcing th Controlled Substances Act
Term
Drug Facts and Comparisons
Definition

A reference book for health care professionals that provides information on drugs according to their therapeutic classifications.

This reference compares the various drugs within each category with other products.

Term
First Dose
Definition
Initial Dose
Term
First-Dose Effect
Definition
An undesired effect of a medication that occurs within 30 to 90 minutes after administration of the first dose.
Term
Food and Drug Administration
Definition
The government agency responsible for administering and enforcing the Food, Drug, and Cosmetic Act wtihin the US
Term
Generic Name
Definition
The name established when the drug is first manufactured. The name is protected for use by only the original manufacterer for a period of 17 years. After that time, the name of the drug becomes public property and can be used by any manufacturer.
Term
Hospital Formulary
Definition
A reference book that lists all of the drugs commonly stocked in the hospital pharmacy. This book provides information about the characteristics of drugs and their clinical usage.
Term
Hypotension
Definition
Low blood pressure; less than normal blood pressure.
Term
Idiosyncrasy
Definition

An unusual, inappropriate response to a drug or to the usual effective dose of a drug. This reaction can be life threatening.

 

ex. anaphylactic chock

Term
Inhalation Medication
Definition
Medication is sprayed or breathed into the nose, throat, and lungs. It is absorbed into teh mucous membrane lining of the nose and throat and by the alveoli of the lungs.
Term
Initial Dose
Definition
The first does of a medication
Term
Intradermal Medication
Definition

Medication inserted just beneath the epidermas, using a syringe and needle.

 

are used for alergy testing, tuberculin skin testing, and some vaccinations

Term
Intramuscular Medication
Definition

Medication injected directly into the muscle.

 

used for administering antibiotics, medications that might be irritating to the layers of the skin and medications that reqire dosages larger than the amount allowed for a subcutaneous injection

Term
Intravenous Medication
Definition

Medication injected directly into the vein, entering the bloodstream immediately.

 

used when medication is needed quickly and for administering medications over a period of time, by adding the mediation to a bag of intravenous fluids

Term
Local Effect
Definition
A response (to a medication) confined to a specific part of the body
Term
Maintenance Dose
Definition
The dose of a medication that will keep the concentration of the medication in the bloodstream at the desired level.
Term
Official Name
Definition

Generic name;

The name established when the drug is first manufactured. The name is protected for use by only the original manufacterer for a period of 17 years. After that time, the name of the drug becomes public property and can be used by any manufacturer.

Term

Over the Counter

(OTC)

Definition
Medication available without a prescription
Term
Package Insert
Definition
An information leaflet placed inside the container or package of prescription drugs. The FDA requires that the drug generic name, indications, contraindications, adverse effects, dosage, and route of administration be described in the leaflet.
Term
Parenteral Medication
Definition
Any route of administration not involving the gastrointestinal tract, e.g., topical, inhalation, or injection
Term
Pharmacist
Definition
One who is licensed to prepare and dispense drugs
Term
Pharmacodynamics
Definition
The study of how drugs interact in the human body.
Term
Pharmacology
Definition
The field of medicine that specializes in the study of drugs, including their source, appearance, chemistry, actions, and uses.
Term
Pharmacy
Definition
A place for preparing or dispensing drugs
Term
Physicians' Desk Reference
Definition
A reference book that provides the same information found in package inserts that accompany each container of medication: description of the drug, actions, indications and usage (why medication is prescribed), contraindications, warnings, precautions, adverse reactions, overdosage, and dosage and administration.
Term
Potency
Definition
Strength
Term
Potentiation
Definition

The effect that occurs when two drugs administered together produce a more powerful response than the sum of their individual effects.

 

Patients who are taking blood thinners are advised to avoid taking aspirin, which will potentiate the thinning effect on the blood.

Term
Rectal Medication
Definition

Medication inserted into the rectum and slowly absorbed into the mucous membrane lining of the rectum. It is in the form of a suppository, which melts as the body temperature warms it, or a retention enema.

 

Advantage: one method of choice when the patient is nauseated or cannot take medications orally.

Disadvantage: absorption is slow and irregular.  

Term
Route of Administration
Definition
The method of introducing a medication into the body.
Term
Side Effect
Definition
An additional effect on the body by a drug thatwas not part of the goal for that medication. Nausea is a common side effect of many drugs.
Term
Standards
Definition
Rules that have been established by control the strength, quality, and purity of medications prepared by various manufactureres.
Term
Subcutanous Medication
Definition

Medication injected into the subcutaneous layer, of fatty tissue, of the skin.

 

are used for administering insulin, hormones, and local anesthetics.

Term
Sublingual Medication
Definition
Medication placed under the tongue, where it dissolves in the patient's saliva and is quickly absorbed through the mucous membrane lining of the mouth.
Term
Systemic Effect
Definition
A generalized response to a drug by the body. The drug has a widespread influence on the body because it is absorbed into the bloodstream.
Term
Tachycardia
Definition
Rapid heartbeat, over 100 beats per minute
Term
Therapeutic Dose
Definition
The dose of a medication that achieves the desired effect.
Term
Tolerance
Definition

The body's decreased reponse to the effect of a drug after repeated dosages.

 

Characteristic of drug addiction

Term
Topical Medication
Definition

Medication applied directly to the skin or mucous membrane for a local effect to the area.

 

Advantage: easy method, convenient

Disadvantage: slow absorption through the skin  

Term
Toxicology
Definition
The study of poisons, their detection, and their effects and establishing antidotes and methods of treatment for conditions they produce and prevention of poisoning.
Term
Trade Name
Definition
Brand name copyrighted by a pharmaceutical company
Term
United States Pharmacopeia
Definition
An authorized publication of the United States Pharmacopeial Convention that contains formulas and information tht provide a standard for preparation and dispensation of drugs. Recognized by the U.S. government as the official listing of standardized drugs.
Term
Vaginal Medication
Definition

Medication inserted into the vagina; may be in the form of a suppository, cream, foam, or tablet.

The medication dissolves as the body temperature warms and melts it.

Term
Oral
Definition

An oral medication is one that is given by mouth and swallowed.

 

This drug is then slowly absorbed into the bloodstream through the lining of the stomach and intestines.

Advantage: easiest and safest method; most economical

Disadvantage: slow method of absorption; possibility of being destroyed by the gastric juices 

Term
Sublingual
Definition

A sublingual medication is one that is placed under the tongue.

 

Quickly absorbed through the mucous membrane lining of the mouths; also known as hypoglossal

 

Advantage: more rapid absorption rate than oral; higher concentration of medication reaches the bloodstream by not passing through the stomach

Disadvantage: not a convenient rought of administration for bad-tasting medicine or those that might irritate the mucous membrane.  

Term
Buccal
Definition

is one that is placed in the mouth next to the cheek. It is in tablet form.

The medication is absorbed into the mucous membrane lining of the mouth.

Advantage: more rapid absorption rate than oral; higher concentration of medication reaches the bloodstream by not passing through the stomach; effects of the medication stop if the tablet is removed

Disadvantage: possibility of swallowing the pill 

Term
Inhalation
Definition

Medications administered by inhalation are those that are sprayed or inhaled into the nose, throat, and lungs.

Medication is absorbed into the mucous membrane lining of the nose and throat and by the alveoli of the lungs.

 

Advantage: good absorption due to large surface contact area; provides rapid treatment

Disadvantage: sometimes difficult to regulate the dosage; not suitable for medications that might irritate the mucous membrane lining 

Term
Transdermal
Definition

A method of applying a drug to unbroken skin. The drug is absorbed continuously and produces a systemic effect.

 

medications is packages in an adhesive-backed disk that releases medication into the bloodstream at a controlled rate.

Advantage: good method of administring medications that need to be released slowly into the bloodstream over a period of time.

 

Term
Parenteral
Definition
Any route of administration not involving the gastrointestinal tract, e.g., topical, inhalation or injection.
Term
Analgesic
Definition

Relieves pain

 

ex. acetylsalicylic acid (aspirin)

acetaminophen (Tylenol)

Term
Anesthetic
Definition

Partially or completely numbs or eliminates sensitivity with or without loss of consciousness.

 

ex. Lidocaine (xylocaine)

Term
Antiarrhythmic
Definition

Corrects cardias arrhythmias (irregular beats)

ex. diagoxin (Lanoxin)

propranolol

hydrochloride (Inderal)

Term

Antibiotic

(anti-infective)

Definition

Stops or controls the growth of infection-causing microorganisms

 

Term
Anticoagulant
Definition
Prevents clot continuation and formation
Term
Anticonvulsant
Definition
prevents or relieves convulsions (seizures)
Term
Antidepressant
Definition
prevents, cures, or alleviates mental depression
Term
Antidiabetic
Definition
Helps control the blood sugar level
Term
Antiemetic
Definition
Prevents or relieves nausea and vomiting
Term
Antitussive
Definition
Relieves cough due to various causes
Term
Antiulcer Agent
Definition
Treats and prevents peptic ulcer and gastric hypersecretion
Term
Antiviral Agent
Definition
Treats various viral conditions such as serious herpes virus infection, chickenpox, and influenza A
Term
Beta Blocker
Definition
Treats hypertension, angina, and various abnormal heart rythms
Term
Bronchodilator
Definition
Expands the bronchial tubes by relaxing the bronchial muscles
Term
Calcium Channel Blocker
Definition
Treats hypertension, angina, and various abnormal heart rhythms
Term
Hormone
Definition
treats deficiency states where specific hormone level is abnormally level
Term
Hypnotic
Definition
Induces sleep or dulls the senses
Term
Laxative
Definition
Prevents constipation or promotes the emptying of the bowel contents with ease.
Term
Lipid-Lowering Agent
Definition
Reduces blood lipd (fat) levels)
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