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Chapter 21
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36
Biochemistry
Undergraduate 2
04/17/2012

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Term
NAD+ vs. NADH
1 High energy vs. low energy?
2. oxidized coenzyme?
3. Reducing agent vs. Oxidizing agent?
4. NAD+ --> NADH
endergonic/exergonic?
5. Purpose?
Definition
1. High= NADH; Low= NAD+
2. NAD+ is the oxidizied coenzyme.
3. NAD+ = oxidizing agent
NADH = reducing agent
4. NAD+ -> NADH = Endergonic
5. Purpose: Recieve energy from food and take it to be transferred to ATP.
Term
Oxidative Phosphorylation
IN:
1. Reduced _______
2. ________
3. ________ groups
4. ________

OUT:
5. Oxidized _______
6. ________
7. ________
Definition
IN:
1. Reduced Cofactors (NADH)
2. Oxygen
3. Phosphate Groups (Pi)
4. ADPs

OUT:
5. Oxidized Cofactors (NAD+)
6. Water
7. ATPs
Term
In Oxidative phosphorylation, how is the concentration gradient maintained?
Definition
Answer: By using O2 to make water.
Term
Define Kinetic Energy.
1. Examples?
Definition
Definition: Anything that moves

Examples:
-Motion of Objects
-Light
-Sound
-Electricity
-Heat
Term
In Oxidative phosphorylation, where does the energy to form the concentration gradient come from?
Definition
Answer: NADH
Term
Citric Acid Cycle:
IN:
1. ______ (2 Cs)
2. Oxidized _______ (4)
3. 1 _____ equivalent
4. _____(inorganic phosphate ion)

OUT:
5. 2 _____
6. ________
7. reduced ______ (4)
8 1 _____ equivalent.
Definition
IN:
1. Acetyl CoA (2 Cs)
2. Oxidized coenzymes NAD+ (4)
3. 1 ADP equivalent
4. Pi (inorganic phosphate ion)

OUT:
5. 2 CO2
6. Reduced coenzymes NADH (4)
7. 1 ATP equivalent.
Term
Define Glycogen
1. purpose?
Definition
Definition: Molecule animals use for short term quick access storage as carbohydrates. [Polyglucose]

Purpose: energy storage in animals.
Term
Define Amylose
1. purpose?
Definition
Definition: Carbohydrate plants make [polyglucose]

Purpose: Storage of energy in plants for later use.
Term
Define Potential Energy
1. examples
Definition
Definition: Anything that could release energy

Examples:
-Objects at an elevation
-Batteries
-Gasoline
-Nuclear
-Chemical Bonds.
Term
Exergonic
1. Define
2. Oxidation vs reduction?
3. Examples
4. Products vs reactants.
Definition
1. Definition: Spontaneous reactant that releases.
2. Oxidation
3. Examples: Oxidation, burning wood, push a brick wall.
4. Products vs Reactants: reactants have more energy.
Term
Energy
Definition
Term
What is the catabolic system we use in our bodies?
Definition
Answer: Energy from food to NADH
NADH to ATP
Term
Which molecule contains Vitamin B?
-FADH2 -Coenzymes A
-ATP -Citric Acic
-NADH -FAD+
-NAD+
Definition
Answer: FADH2, FAD, NADH, NAD+, Coenzymes A
Term
Mitochondria
1. Define
2. What happens here?
3. What is imbedded into the inner membrane?
4. Where is the pH lower?
Definition
1. Power house of the cell
2. Citric Acid Cycle
Oxidative phosphorylation
3. OxPhos proteins
4. in the inter-membrane space.
Term
1._____ ATP for every

2._____ C Fragment
Definition
Answer:
1. 12 ATP for every
2. 2 C Fragments (acetic acid)
Term
Where is most of the CO2 from catabolism produced?
Definition
Answer: Citric Acid Cycle
Term
True or False:
During OxPhos, the coenzymes (NAD) combine with oxygen.
Definition
Answer: False, they are oxidized.
Term
Citric Acid Cycle
1. Purpose?
2. How does energy go in?
3. How does energy come out?
4. Activators and Inhibitors?
Definition
1. Suck energy out from Acetyl CoA and put to reduced coenzymes
2. Goes in as Carbon in CoA
3. Comes out in 90% of reduced coenzymes (NADH) 10% of ATP equivalent
4. Activators: ADP, NAD+
Inhibitors: ATP, NADH
Term
In what form do Carbons enter the Citric Acid Cycle?
Definition
Answer: Acetyl CoA
Term
In what form does the Redox Coenzymes exit the Citric Acid Cycle?
Definition
Answer: NADH
Term
What happens if your body doesn't have enough B Vitamins?
Definition
Answer: Can't make ATP
Term
What are the 3 main nutrients involved in the catabolism of food?
Definition
Answer: [Triglycerides]
Lipids (glycerol and fatty acids)
Carbohydrates (glucose and other sugars)
Protein (Amino Acids)
Term
Catabolism vs. Anabolism
1. Which uses ATP?
2. Which is involved in the formation of ATP?
3. Exergonic vs endergonic?
Definition
1. Anabolism
2. Catabolism
3. Anabolism is endergonic
Catabolism is exergonic.
Term
Antioxidants
1. Purpose
2. What vitamins do they contain?
3. Where can these be found (food) examples?
Definition
1. neutralize free radicals ->" protection"
2. Vitamin A, C, E
3. Foods with dark color; Exampl: Spinach, blueberries, raisins, beets, cherries.
Term
Coenzymes A
1. CoA is a _____ group
2. Purpose
3. True or False: Contains B Vitamin?
Definition
1. CoA is an acetyl-carrying group
2. Purpose: get a high energy Acetyl group from food and take them to where they're needed.
3. True
Term
True or False?
Bonds between phosphate groups have higher energy in them than most bonds.
1. Where are these bonds found?
Definition
Answer: True
Can provide enough energy from almost any reactant.

1. ATP
Term
1 glucose= _______ ATP Molecules
Definition
Answer: 26 ATP Molecules
Term
Where is the only place O2 is used in catabolism?
Definition
Answer: Oxidative Phosphorylation.
Term
Define Anabolism
1. Big vs small?
Definition
Definition: Metabolic reactant pathways that build larger biological molecules including those can store energy from smaller pieces "Building"

1. Big vs Small: Small -> Big
[ATP -> ADP +Pi]
Smaller molecule -> complicated Molecule
Term
What is involved in the transport of acetyl groups?
Definition
Answer: Acetyl CoA
Term
Free Radicals:
1. Define
2. What is the body's response
3. What do they do in the body?
4. What do they contain that makes them harmful?
5. True or False: Our Body makes free radicals.
Definition
1. Harmful oxygen by-products
2. Antioxidants
3. Cause cell injury; break covalent bond.
4. An extra unpaired electron
5. TRUE
Term
ATP
1. What does it stand for?
2. What can be found in its structure?
3. ATP is a truck for _____
4. ATP contains _____ bonds
5. True or False: Contains B vitamin?
6. Name of the enzyme that converts ADP-> ATP
Definition
1. Adenosine triphosphate.
2. Adenine, Ribose
3. ATP is a truck for just the right amount of Energy
4. ATP contains high energy phosphate bonds.
5. False.
6. ATP synthesis.
Term
Define Catabolism
1. Big vs. small?
Definition
Definition: Metabolic reaction pathways that break down food molecules and release biochemical energy.

1. Big Vs Small: Big -> Small.
Term
Define Metabolism
Definition
Definition: all chemical reactions that take place in an organism

Anabolism + Catabolism
Term
Principle source for energy for animals?
Definition
Answer: Oxidation of glucose.
Term
Endergonic
1. Define
2. Oxidation vs. Reduction
3. Examples
4. Reactants vs. Products
Definition
1. Reaction that needs energy to occur
2. Reduction
3. Examples: Building anything, Reduction, Making a brick wall.
4. Products have more energy.
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