Term
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Definition
| Dissolves, reaches bloodstream |
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Term
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Definition
| dosage and routes of administration |
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Term
| Advantages of aerosolized agents by inhalation |
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Definition
| 1. smaller doses 2. fewer side effects 3. rapid onset of action 4. targeted to respiratory system 5. painless administration & safe |
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Term
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Definition
| binds to receptor and causes reaction |
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Term
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Definition
occurs in the aqueous compartments of the body, such as the interstitial spaces or within a cell. Diffusion occurs by a concentration gradient. |
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Term
| Carrier mediated transport |
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Definition
| transport of amino acids, sugars, peptides, etc. |
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Term
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Definition
| The name indicating the drug's chemical structure |
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Term
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Definition
| A name/number assigned by a manufacturer to an experimental chemical that shows potential as a drug. |
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Term
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Definition
| depends on PKp (PH at which drug is 50/50 ionized/non-ionized), ambient PH, whether drug is weak acid or base |
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Term
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Definition
| chemical, code, official, generic, and trade (or brand) |
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Term
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Definition
| oral, suppository, under tongue (sublingual), trough gastric tube |
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Term
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Definition
| The name assigned by the United States Adopted Name (USAN) Council when chemical appears to have therapeutic use and the manufacturer wishes to market the drug. Often loosely based on chem. structure. A.k.a. "non-proprietary". |
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Term
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Definition
| for systemic or local effect |
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Term
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Definition
| drug must be lipid-soluble, to diffuse across membrane |
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Term
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Definition
| targeted/limited to the area of treatment |
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Term
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Definition
| The liver is a primary site of drug metabolism and biotransformation, and the kidneys are the site of primary drug excretion, although drug and metabolites can be excreted in the feces as well. |
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Term
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Definition
| Airway surface liquid, epithelial cells, basement membrane, interstitium, capillary vascular network. |
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Term
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Definition
| If drug is FDA approved, generic name becomes official name |
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Term
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Definition
| drugs for rare diseases with higher cost to develop than expeted return |
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Term
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Definition
| Physician's Desk Reference |
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Term
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Definition
Injectable:
Intravenous - IV
Intramuscular - IM
Subcutaneous - SC |
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Term
|
Definition
| effects of the drug on body |
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Term
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Definition
| what the drug does to the body |
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Term
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Definition
| factors determining absorbtion, distribution, metabolism, breakdown, and elimination |
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Term
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Definition
| what body does to the drug |
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Term
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Definition
| The study of drugs (chemicals), including their origin, properties, and interactions with living organisms. |
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Term
| Phases of drug from dose to effect |
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Definition
1. administration phase
2. pharmacokinetic phase
3. pharmacodynamic phase |
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Term
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Definition
| engulfment (as in WBC destroying bacteria) |
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Term
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Definition
| Prevention of health problems |
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Term
| Respiratory care pharmacology |
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Definition
| the application of pharmacology to the treatment of pulmonary disorders |
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Term
|
Definition
1. Enteral
2. Parenteral
3. Inhalation
4. Transdermal
5. Topical |
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Term
| Source of drug preparation |
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Definition
| Most common: chemical synthesis or animal, plant and mineral |
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Term
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Definition
| Pertains to the whole body |
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Term
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Definition
| Marketing name by drug company |
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Term
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Definition
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Term
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Definition
| United States Pharmacopeia - National Formulary |
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Term
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Definition
| a drug or chemical that is able to bind to a receptor (has affinity) but causes no response (zero efficacy) |
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Term
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Definition
| a drug or chemical that is able to bind to a receptor (has affinity) but causes no response (zero efficacy) |
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Term
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Definition
| An effect that is the opposite of, or unusual, or an absence of effect, compared with the predicted usual effect in an individual. |
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Term
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Definition
| An allergic or immune-mediated reaction to a drug, which can be serious, requiring airway maintenance or ventilatory assistance. |
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Term
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Definition
| Describes a decreasing intensity of response to a drug over time. |
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Term
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Definition
| Describes a rapid decrease in responsiveness to a drug. |
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Term
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Definition
refers to hereditary differences in the way the body handles specific drugs |
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Term
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Definition
Approximately 1 in 3000 individuals has a genetically determined variant of this enzyme. As a result, a patient may take several hours to recover from the drug and begin to breathe spontaneously |
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