Term
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Definition
| defective osteoclast-mediated bone resorption, unable to acidify howships; chalk like bones |
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Term
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Definition
genetic disorders caused by type 1 collagen defect, very fragile bones
-blue sclera, hearing loss, small teeth |
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Term
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Definition
defect in normal cartilage development
causes plates to seal early, most common cause of dwarfism |
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Term
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Definition
focal derangements of bone resorption and deposition
-pain, bony deformity, warmth, hearding, heart failure |
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Term
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Definition
| gradual and progressive loss of bone mass, bone fractures and pain |
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Term
| Osteolytic stage 1(Paget) |
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Definition
| bone resorption dominates |
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Term
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Definition
| bone deposition approximates resorption rates, new bone is abnormal |
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Term
| Osteosclerotic stage 3 (paget) |
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Definition
| resorption declines harder and more dense bone tissue is formed |
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Term
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Definition
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Term
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Definition
| younger age, osteoclasts regenerate too much, mostly in spongy bone |
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Term
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Definition
| age related bone loss, after age 70, reduced degree of bone deposition during remodeling w/ osteoblasts |
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Term
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Definition
bone loss due to identifiable
physical inactivity, caffeine ingestion
calcium, vitamin D, hormones, biphosponates |
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Term
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Definition
| impairment of mineralization in an essentially normal organic matrix (softened bone) |
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Term
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Definition
children interferes with growth plates before they are closed; vit D deficiency
-bowed legs, +fractures, pigeon breast |
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Term
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Definition
adult counterpart, growth plates closed
caused by: GI malabsorption, renal defect, faulty activation in liver, limited sunlight |
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Term
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Definition
bone inflammation in response to infection by pyogenic bacteria
Staphylococcus, E-Coli, Salmonella
chronic recurrence |
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Term
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Definition
| primary tumor arising from prostate, breast, thyroid, lung, kidney |
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Term
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Definition
| bone breakdown, weakening w/ fractures |
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Term
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Definition
| grows away from the bone, benign |
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Term
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Definition
| most common malignant, metastasizes to lung, long bones |
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Term
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Definition
| 15% arise from previous encounters, pelvis, ribs, femur, humerus |
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Term
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Definition
| rare, manifests as a mass in diaphysis of long bones 10-15 yr males |
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Term
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Definition
most common joint disease in America, degeneration of articular cartilage
-age, gender, race, obesity |
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Term
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Definition
| degeneration of bone into hard, ivory like surface |
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Term
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Definition
| small fractures dislodge pieces into joint of bone |
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Term
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Definition
autoimmune affects many tissues, but mainly joints, idiopathic
rheumatoid factor: Igm against IgG |
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Term
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Definition
| crystals in joint caused by uric acid |
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Term
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Definition
crystals of calcium pyrophosphate dehydrate into articular cartilage leading to inflammation
-knee most common |
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Term
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Definition
axial skeleton, stiffening of the spine
-men, HLA-B27
Bamboo spine: ligaments attach to bone |
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Term
| Duchenne Muscular dystrophy |
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Definition
| x linked recessive-- males, mutation of dystrophin gene |
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