Term
| what functional group is found in more medications than any other type of functional group? |
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Definition
| nitrogen-containing functional groups |
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Term
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Definition
| oreganic derivatives of ammonia in which one or more of the hydrogens are replaced by an aromatic or alkyl group |
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Term
| what categories are amines put into |
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Definition
| primary, secondary, tertiary |
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Term
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Definition
| the nitrogen is attached to one other R group |
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Term
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Definition
| the nitrogen is bonded to two R groups |
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Term
| what suffix is used when naming amines? |
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Definition
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Term
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Definition
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Term
| what is the simplest aromatic amine? |
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Definition
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Term
| which forms the strongest hydrogen bonds: amines or alcohols? |
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Definition
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Term
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Definition
| because nitrogen is less electronegative than oxygen |
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Term
| are the boiling points for amines higher or lower than alcohols? |
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Definition
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Term
| the bp for tertiary amines is less than the other amines. Why? |
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Definition
| because tertiary amines are not able to form hydrogen bonds among themselves |
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Term
| Amines with fewer than (?) carbons are soluble in water? |
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Definition
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Term
| what is the most distinguishing feature of amines? |
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Definition
| their behavior as weak bases |
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Term
| in acidic solution, is the salt or amine favored |
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Definition
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Term
| how are quaternary ammonium salts different from other ammonium salts |
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Definition
| there is no hydrogen attached |
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Term
| amines reac with acid chlorides or acid anhydrides to form |
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Definition
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Term
| what is the characteristic functional group of amides |
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Definition
| a carbonyl group attached to a nitrogen |
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Term
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Definition
| the single bond linking the carbonyl carbon and nitrogen atoms in the group |
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Term
| what must be used in the formation of amides |
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Definition
| primary and secondary amides |
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Term
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Definition
| a class of drugs structurally similar to epinepherine used to stimulate the CNS |
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Term
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Definition
| a class of nitrogen containing organic compounds obtained from plants |
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Term
| what state is formamide at room temp? |
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Definition
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Term
| what state are all the other unsubstituated amides? |
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Definition
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Term
| are the mp and bp of amides high or low? |
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Definition
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Term
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Definition
| because amides can form a complex network of intermolecular hydrogen bonds |
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Term
| why do disubstituated amides have a lower boiling point than monosubstiuated or unsubstituated amides? |
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Definition
| because the alkyl or aromatic groups attached make less room for hydrogen, thus there is less hydrogen bonding |
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Term
| are amides water soluble? |
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Definition
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Term
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Definition
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Term
| during hydrolysis, the amide is cleaved into what two compounds? |
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Definition
| a carboxylic acid and an amine or ammonia |
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Term
| what are the products when an amide undergoes hydrolysis under acidic conditions? |
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Definition
| carboxylic acid and an amine salt |
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Term
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Definition
| carboxylate acid and an amine |
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