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Chapter 16 - Respiratory Physiology
Fox, Chapter 16
24
Physiology
Professional
04/19/2012

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Term
two zones
Definition
1. respiratory zone: gas exchange
2. conduction zone: gets air into respiratory zone
Term
respiration
Definition
1. ventilation (breathing)
2. gas exchange btwn blood/lungs and btwn blood/tissues
Term
gas exchange in lungs
Definition
1. diffusion
2. higher O2 concentration in lungs, so diffuses into blood
3. higher CO2 conc. in blood, so diffuses out
Term
alveoli
Definition
1. air sacs in lungs where gas exchange happens
2. 300 million of them
Term
type I alveolar cells
Definition
1. 95-97% total surface area where gas exchange occurs
Term
type II alveolar cells
Definition
1. secrete pulmonary surfactant and reabsorb sodium and water
Term
thoracic cavity
Definition
1. heart, trachea, esophagus, and thymus
2. lungs fill the rest of the cavity
Term
ventilation
Definition
1. air moves from higher to lower pressure
Term
inhalation
Definition
1. intrapulmonary pressure is lower than atmospheric pressure
Term
exhalation
Definition
1. intrapulmonary pressure is greater than atmospheric pressure
Term
intrapleural pressure
Definition
lwoer than intrapulmonary and atmospheric pressure in both inhalation and exhalation
Term
Boyle's law
Definition
pressure of gas is inversely proportional to its volume
Term
elasticity
Definition
lungs return to initial size after being stretched
Term
surface tension
Definition
1. resists distension
2. exerted by fluid secreted in alveoli
3. raises pressure of alveolar air
Term
surfactant
Definition
1. excreted by type II alveolar cells
2. reduces surface tension btwn water molecules
3. prevents collapse
Term
tidal volume
Definition
1. amount of air expired or inspired in quiet breathing
Term
vital capacity
Definition
1. maximum amount of air that can be forcefully exhaled after a maximum inhalation
Term
total lung capacity
Definition
1. amount of gas in the lungs after a max. inspiration
Term
restrictive disorders
Definition
lung tissue is damaged
vital capacity reduced
forced expiration normal
ex: emphysema
Term
obstructive disorders
Definition
lung tissue normal
vital capacity normal
forced expiration reduced
ex: asthma
Term
partial pressure
Definition
1. pressure of an individual gas
2. = % of that gas X total pressure
Term
hyperventilation
Definition
- CO2 falls
- pH rises
Term
acidosis
Definition
- low pH
respiratory acidosis: hypoventilation
metabolic acidosis: loss of bicarbonate, excessive acid production
Term
alkalosis
Definition
high blood pH
- respiratory alkalosis: hyperventilation / low CO2
- metabolic acidosis: overproduction of bicarbonates
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