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Chapter 14
micro chapter 14
45
Microbiology
Undergraduate 1
04/04/2011

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Term
pathology
Definition
the scientific study of disease
Term
etiology
Definition
the study of a cause of a disease
Term
pathogenesis
Definition
the manner in which a disease develops
Term
infection
Definition
colonization of the body by pathogens; the presence of a particular type of organism in a part of the body where it is normally not found
Term
disease
Definition
an abnormal state in which the body is not functioning normally; occurs when an infection results in any change from a state of health
Term
commensalism
Definition
one organism benefits, the other is unaffected
Term
microbial anatagonism
Definition
the normal microbiota can benefit the host by preventing the overgrowth of harmful organisms
Term
normal microbiota protect the host by...
Definition
occupying niches that pathogens might occupy, producing acids, and producing bacteriocins
Term
bacteriocins
Definition
proteins that will kill similar species but leave the producer intact
Term
probiotics
Definition
live microbes applied to or ingested into the body, intended to exert a beneficial effect
Term
symptom
Definition
change in body function that subjective changes that are not apparent to an observer (pain, headache)
Term
sign
Definition
objective changes that the physician can observe and measure
Term
syndrome
Definition
a specific group of symptoms or signs that can accompany a particular disease
Term
communicable
Definition
spreads from one host to another directly or indirectly
Term
contagious
Definition
diseases that are easily spread from one person to another
Term
incidence
Definition
number of people in a population who develop a disease during a particular time period; indicator of the spread of a disease
Term
prevalence
Definition
number of people in a population who develop a disease at a specified time; regardless of when it first appeared; both old and new cases; indicator of how seriously and how ling a disease affects a population
Term
endemic disease
Definition
constantly present in a population
Term
epidemic disease
Definition
many people in a given area acquire a certain disease in a relatively short period
Term
pandemic disease
Definition
an epidemic disease that occurs worldwide
Term
herd immunity
Definition
immunity in most of a population; immunity in part of the population protects the rest of the population.
Term
focal
Definition
a local infection enters the blood or lymph and spreads to other specific parts of the body
Term
septicemia
Definition
blood poisoning, a systemic infection arising from the multiplication (growth) of pathogens in the blood
Term
bacteremia
Definition
bacteria in the blood
Term
SIRS
Definition
severe inflammatory response syndrome (sepsis if due to a bacterial infection)
Term
incubation period
Definition
time interval between the initial and the first appearance of any signs or symptoms
Term
prodromal period
Definition
relatively short period that follows the period of incubation in some diseases characterized by early, mild symptoms of disease (general aches, malaise)
Term
period of convalescence
Definition
the person regains strength and the body returns to its prediseased state
Term
zoonoses
Definition
diseases that occur primarily in wild and domestic animals and can be transmitted to human
Term
nonliving
Definition
two major reservoirs are soil and water; improperly prepared foods
Term
fomite
Definition
any nonliving object involved in the spread of an infection
Term
droplet
Definition
microbes are spread in droplet nuclei that travel only short distances
Term
vectors
Definition
arthropods, especially fleas, ticks and mosquitos
Term
biological
Definition
an active process of biting and the disease reproducing within the vector
Term
nosocomial infections
Definition
one that does not show any evidence of being present or incubating at the time of admission to the hospital; it is acquired as a result of the hospital stay and other healthcare facilities. 5-15% of all hospital patients
Term
epidemiology
Definition
study of where diseases occur and how they are transmitted in populations
Term
john snow
Definition
1848-1849. mapped cholera occurrence in London
Term
ignaz semmelweis
Definition
1846-1848. number of births and maternal deaths and hand washing prevented puerperal sepsis (childbirth fever)
Term
florence nightingale
Definition
1858. recorded statistics of epidemic typhus in the english civilian and military populations
Term
descriptive
Definition
collection and analysis of data that describes the occurrance of the diseases under study; information about the affected individual and the place and period in which the disease occurred; usually retrospective (snow)
Term
analytical
Definition
comparison of a diseased group and a health group; case control method- looks for factors that might have preceeded the disease (nightengale); cohort methods; studies two populations; one that has had contact with the agent causing a disease and another that has not (blood transfusion)
Term
morbidity
Definition
incidence of a specific notifiable disease
Term
mortality
Definition
deaths from notifiable diseases
Term
morbidity rate
Definition
number of people affected by a disease in a given period of time in relation to the total population
Term
mortality rate
Definition
the number of deaths resulting from a disease in a population in a given period of time in relation to the total population
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