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Chapter 13 (quiz 9)
Microbe-human interations
44
Microbiology
Undergraduate 2
04/13/2013

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Term
resident biota?
Definition
human as a habitat
Term
Sites known to harbor bacteria
Definition
all exposed to external environment!
-skin
-respiratory tract
-gastrointestinal tract
-urethra
-external genitalia
-vagina
-external ear canal
-external eye
Term
transient microbes?
Definition
-do not normally reside, just passing through
-most are harmless, some are pathogens
Term
resident microbes?
Definition
-each each has particular populations
-changes over time
Term
Opportunists
Definition
cause disease when given the opportunity
-break down in immunity
-certain medical treatments
-implantation of devices
Term
Methods to acquire the normal microbiota
Definition
1. birth canal
2. food
3. breathing
4. natural succession (with age)
Term
What is a pathogen?
Definition
a microbe whose relationship with its host is parasitic and results in infection and disease
Term
What is infection?
Definition
the colonization of an organism by microorganism-with out without disease
Term
what is communicable?
Definition
the ability of a disease causing microorganism to be spread between indivuals
Term
What are virulence factors?
Definition
microbial components that contribute to the ability to cause disease in a susceptible host
Term
What is virulence?
Definition
it is the degree of pathogenicity;
determined by its ability to establish itself in the host and cause damage
Term
What is pathogencity?
Definition
an organisms potential to cause infection or disease
Term
Steps to infection
Definition
1. Finding a portal
2. attaching firmly
3. surviving host defences
4. causing damage
5. exiting host
Term
Different portals of entry
Definition
skin. gastrointestinal tract, respiratory (great number), urogenital, pregnancy and bith
Term
TOURCH
Definition
toxoplamosis, other, rubella, cytomegalovirus, herpes simplex
Term
Inoculating does
Definition
number of microbes needed to be present to cause infection
microbes with smaller IDs have greater virulence
Term
3 ways the microbes attach to the host
Definition
1. fimbriae
2. capsules
3. spikes
Term
How do the microbes survive the host?
Definition
avoiding phagocytes with anti-phagocytic factors, and some can survive inside the phagcoytes after ingestion
Term
how do the microbes cause the disease?
Definition
exoenzymes, toxins, or block phagocyte response
Term
What do the extracelluar enzymes do?
Definition
the break down and inflict damage on tissues or dissolve that host's defense barriers
Term
Exotoxins?
Definition
effect: specific ell types
composition: small proteins
release: secreted from live cell
Term
Endotoxins?
Definition
effect: systemic, fever, inflammation
composition: lipopolysaccharides
release: released by cell via shedding or during lysis
Term
Necrosis?
Definition
accumulated damage leads to cell and tissue death
Term
progression of infection
Definition
1. incubation
2. prodormal "i feel a little off"
3. invastion "mac truck ran me over"
4. Convalescence- not great but better, usually when people stop there antibiotics
5. Recovery
Term
What is a sign?
Definition
any OBJECTIVE evidence of disease as noted by another... temperature, rash, ect.
Term
what is a symptom?
Definition
the SUBJECTIVE evidence of disease as sensed by patient... my stomach hurts
Term
what is a syndrome?
Definition
when a disease can be identified or defined by a certain complex of signs and symptoms
Term
Signs and symptoms of inflammation
Definition
fever, pain, soreness, swelling.
edema.
granulomas and abscesses.
lymphadenitis.
lesions
Term
Signs of infection in the blood?
Definition
changes in the number of circulating white blood cells
Term
Leukocytosis?
Definition
high WBCs
Term
Leukopenia?
Definition
low WBCs
Term
What is septicemia?
Definition
a general state in which microorganisms are multiplying in the blood and are present in large numbers
Term
What are some portals of exit?
Definition
respiratory, salivary portals, skin scales, fecal exit, urogenital tract, removal of blood or bleeding
Term
What is latency?
Definition
a dormant state
Term
What is a reservoir?
Definition
the primary habitat in the natural world from which a pathogen originates
Term
what is a source?
Definition
the individual or object from which an infection is actually acquired
Term
What is a carrier?
Definition
an individual who inconspicuously shelters a pathogen and spreads it to others without any notice
Term
Types of carriers?
Definition
asymptomatic
incubation
convalescent
chronic
passive
Term
What is a noncommunicable disease?
Definition
does not arise through transmission of infectious agent from host to host
Term
what is a nosocomial infection?
Definition
infectious diseases that are accuired or developed during a hospital stay
Term
What is an epidemic?
Definition
sudden acute disease outbreak affecting many
Term
pandemic?
Definition
a worldwide epidemic
Term
endemic?
Definition
chronic occurrence in a geographical region
Term
sporadic?
Definition
random small outbreaks
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