Term
| Characteristics of Viruses |
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Definition
| Serious diseases (rabies, HIV, Hepatitis C, Polio, Yellow Fever, Ebola), Either DNA or RNA, No membrane or organelles, No metabolic activity, Nucleocapsid and then some have Envelope. |
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Definition
| only 1 host due to affinity of viral surface (proteins/glycoproteins) for complementary on host cell wall. "specificity". Others, many diff cells. |
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Definition
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Definition
| Infected Tobacco Mosaic plants, took leaves, ground them very fine to juice, took juice through porcelain filters so no bacteria, put on wounds in healthy ones - got infected! |
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Term
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Definition
| Isolated and Crystalized TMV. |
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Term
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Definition
| Made of protein subunits - Capsomeres (1 or more proteins. |
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Term
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Definition
| Helical, Polyhedral, Complex. |
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Term
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Definition
| Common in animal viruses. Cytoplasmic membrane around the capsid. Acquired when release from host cell. comprised of proteins and phospholipids. |
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Term
| Classification of Viruses |
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Definition
| Intl. Committee on Taxonomy of Viruses. Based on type of NA, presence of envelope, shape, and size. |
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Term
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Definition
| Lytic and Lysogenic. Depend on host cells organelles and enzymes. Lysis & death of host cell. |
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Term
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Definition
| 1.Attachment - tail fiber proteins match. 2.Entry - Lysozyme weakens ppg of wall, tail sheath injects viral DNA at 2200 psi. 3.Synthesis - Viral enzymes degrade DNA and direct synthesis of viral DNA & proteins. 4.Assembly - Assembly of viral components. 5.Release - lysozyme degrades wall and cell lyses (bursts) |
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Definition
| Same but DNA goes into chromosome & virus is inactive (prohpage). when cell replicates, prophage is also replicated and transmited to daughter cells |
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Term
| Replication of Animal Viruses |
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Definition
| Attachment via glycoprotein spikes not tail fibers. Entire virion enters cell. Synthesis in nucleus and cytoplasm. Release by budding, host cell slowly lyses. |
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Term
| Latency of Animal Viruses |
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Definition
| Dormant for months or years |
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Term
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Definition
| uncontrolled cell division. Benign tumers- 1 place, not harmful. Malignant - invade and travel and form cancers. Lose contact inhibition. 1st hit:Protooncogenes to oncogenes. 2nd hit:Virus also into repressor gene. Viruses cause 15% of human cancers |
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Definition
| Epithelial tissue - better cause on surface. see/find faster |
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Definition
| Connective tissue - Deeper in body. |
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Term
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Definition
| Bacteria - plaque assay. Animals&plants - tmv expensive. Eggs - cheap, vaccines problems for allergy to eggs. Tissue - Diploid:embryonic only 100 gen. Continuous: Longer from tumor cells |
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Term
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Definition
| Small circular RNA that infect plants, lack capsid. None infect animals or humans |
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Term
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Definition
| Infectious, lack NA, made of PrP. Ex: Bovine spongiform Encephalopathy, Creutzfeldt-Jakob Disease, Kuru, scrapie, Chronic Wasting Disease. |
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Term
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Definition
| Ingestion of infected tissue, infected transplants, mucous membrane contact, skin abrasions with infected tissue. |
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Term
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Definition
| incineration only. No treatment. |
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