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chapter 12
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27
Biology
Undergraduate 3
08/12/2011

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Term
evol.
mito.
chloroplast
Definition
anerobic pre. eukaryotic cell endocytosed aerobic cell
Term
evol
nuclear membrane
E.R
Definition
prokaryotic cell (DNA) NO NUCLEUS
Term
transportation through compartments
Definition
1. GATED-in and out of the nucleus
2. TRANSMEMBRANE- whole molecule are moved
3. VESSICULAR- small molecules
Term
GATED TRANSPORT
Definition
in and out of nucleus
proteins regulated
Term
TRANSMEMBRANE
Definition
from cytosol to E.R
whole molecules are moved
Term
VESSICULAR
Definition
small molecules are moved
we package cargo
vessicles bud off
Term
signal patch
Definition
regulate membrane transports
Term
gated-in and out of nucleus
Definition
nucleus has pores / complex
Term
NUCLEAR PORE
Definition
each complex moves 500 molecules/sec
Term
PROTEINS OF NUCLEAR MEMBRANE
Definition
cytosolic fibres- transport molecules and cargo
lock in over all shape -octagon shape
Term
column subunits
Definition
Span membrane. link cytosolic structures to nuclear structures
Term
Lumenal subunits
Definition
interact with cloumn and intermembrane space
Term
Annular sub.
Definition
extend into pore, gating mechanism
Term
Nuclear fibrils
Definition
Extend into nucleus
linked together as nuclear basket
Term
NPC
Definition
is highly selective 5KDa passes freely
Term
nuclear import receptors
Definition
bind to NLS TO mediate proteins comming in and out
Term
RAN GTPase
Definition
help in directionality
need accesory molecule
function diff than ATPase
is in nucleus and cytosol
Term
RAN GAP
Definition
cytosol
Term
RAN GEF
Definition
nucleus
Term
TOM COMPLEX
Definition
translocase of outer mito. membrane
Term
SAM transporter
Definition
beta - barrel in outter membrane
Term
TIM COMPLEX
Definition
TIM 23-transport of mito. matrix protein
TIM 22- " of inner membrane protein
Term
OXA
Definition
proteins made w/in mito.
Term
R.E.R
Definition
SORTING PROTEINS
PROTEIN SYNTHESIS
has ribosomes attached
connected to nuclear membrane
Term
S.E.R
Definition
detoxification
mediates b/w golgi and RER
sterin production and lipid synthesis
Term
transport into ER
Definition
1. CO-TRANSLATION translocation- protein syntesis and polypeptied transport occur same time
2. POST- TRANSLATION TRANSLOCATION- Protein synths. firts
polypep. transport later
Term
cytosolic protein determins if ribosome binds
Definition
true
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