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chapter 12
dna replication
28
Biology
11th Grade
04/27/2010

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Term
Pyrimidine bases
Definition
single ringed bases ( thymine, cytosine, and uracil)
Term
Chargaff
Definition

scientist that stated purine bases=pyrimidine bases

a-t

c-g

Term
Crick and Watson
Definition
first scientists to build a DNA structure and measured the width of the helix and the spacing of the bases
Term
double helix
Definition
twisted ladder shape of DNA formed by two strands of nucleotides
Term
histones
Definition
beadlike proteins that DNA coils around
Term
nucleosome
Definition
formed from negatively charged phosphate groups and positively charged histone proteins
Term
semiconservative replication
Definition
parental strands of DNA separate, serve as templates, and produce DNA molecules that have one strand of parental DNA and one new strand
Term
DNA helicase
Definition
an enzyme responsible for unwinding and unzipping the double helix
Term
DNA polymerase
Definition
enzyme that catalyzes the addition of appropriate nucleotides using free nitrogen bases and attaching them to the new DNA strand
Term
DNA ligase
Definition
links the two sections of DNA
Term
Eukaryotic replication
Definition
DNA unwinds in multiple areas and multiple replications occur at the same time
Term
prokaryotic replication
Definition
circular DNA strand is opened at the one origin in the replication process
Term
messanger RNA, mRNA
Definition
long strand of RNA nucleotides that are formed complemetary to one strand
Term
Ribosomal RNA, rRNA
Definition
associates with proteins to form ribosomes in the cytoplasm and is the most unique form of genetic information
Term
transferRNA, tRNA
Definition
smaller segments of RNA nucleotides that transport amino acids to the ribosome
Term
Transcription
Definition
DNA code is transferred to mRNA in the nucleus
Term
RNA polymerase
Definition
enzyme that regulates RNA synthesis, binds to a specific section where an mRNA will be synthesized. ( unzipps and pairs back up)
Term
template strand
Definition
strand of DNA that is read by RNA polymerase
Term
introns
Definition
intervening sequences not found in final mRNA and arent copied
Term
Exons
Definition
coding sequences that remain in the final mRNA
Term
codon
Definition
three-base code in DNA or mRNA
Term
translation
Definition
tRNA molecules act as the interpreters of the mRNA codon sequence
Term
anticodon
Definition
3-base coding sequence at the middle fold opposite of the codon
Term
mutation
Definition
permanent change occurs in a cells DNA
Term
mutagens
Definition
substances which cause mutation
Term
point mutation
Definition
type of DNA mutation involving the change in just one base pair
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