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Chapter 12 - Muscle Contraction and Neural Control
Fox, Chapter 12
34
Physiology
Professional
04/16/2012

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Term
skeletal muscle action steps
Definition
1. a muscle shortens when it contracts
2. places tension on tendons connecting it to bone
3. moves the bone at a joint
4. that bone is attached at the muscle insertion
5. the muscle is attached to a bone that doesn't move at the muscle origin
Term
flexor vs. extensor muscles
Definition
1. flexor muscles: decrease the angle btwn two bones at a joint
2. extensor muscles: increase the angle btwn two bones at a joint
Term
skeletal muscle actions (8)
Definition
1. extensor
2. flexor
3. abductor
4. adductor
5. levator
6. depressor
7. rotator
8. sphincter
Term
abductor vs. adductor muscles
Definition
1. abductor: moves limb away from midline of body
2. adductor: moves limb toward midline of body
Term
levator vs. depressor muscles
Definition
1. levator: moves insertion upward
2. depressor: moves insertion downward
Term
muscle fibers
Definition
1. have plasma membranes called sarcolemma
2. are multinucleated
3. are striated
Term
I bands vs. A bands (muscle fibers)
Definition
I bands: lIght bands
A bands: dArk bands
Term
motor unit
Definition
1. single motor neuron and all the muscle fibers it innervates
2. contraction strength comes from motor unit recruitment
3. muscle fibers contract at once
Term
striations
Definition
1. sarcomere: area from one Z line to the next
2. titin: protein that anchors in the thick filaments and allows elastic recoil
Term
sliding filament theory
Definition
1. when muscle contracts, sarcomeres shorten
- A bands don't shorten
- I bands shorten, but thin filaments don't
- Thin filaments slide toward the H zone (center)
Term
thick and thin myofilaments
Definition
thick: composed of protein MYOSIN
thin: composed of protein ACTIN
- have proteins called tropomyosin and troponin that prevent myosin binding at rest
Term
cross bridges
Definition
1. sliding is produced by several cross bridges that form btwn myosin and actin
2. power stroke (myosin head yanks the actin)
3. ADP is released and a new ATP binds
4. myosin releases actin
5. ATP is split
6. myosin head straightens out and binds to actin further back
Term
regulation of contraction
Definition
1. tropomyosin physically blocks cross bridges
2. troponin complex
Term
troponin complex
Definition
troponin I - inhibits binding of myosin
troponin T - binds to tropomyosin
troponin C - binds to calcium
Term
sarcoplasmic reticulum (SR)
Definition
1. modified endoplasmic reticulum that stores Ca2+ when muscle is at rest
2. Ca2+ diffuses out of calcium channels when muscle fiber is stimulated
3. Ca2+ is actively pumped back into the SR at the end of a contraction
Term
twitch
Definition
when a muscle quickly contracts and relaxes after a single shock or voltage
Term
summation
Definition
when a second shock is applies immediately after the first, the second twitch partially piggybacks the first
Term
tetanus
Definition
1. increasing the frequency of electrical shocks decreases the relaxation time btwn twitches
2. complete tetanus: when NO relaxation at a specific frequency (plateau)
Term
treppe
Definition
as the voltage is increased, the number of muscle fibers in vitro increases
(staircase effect)
Term
isotonic vs. isometric contractions
Definition
Isotonic: muscle fibers shorten when the tension produced is JUST GREATER than the load.

Isometric: muscles can't shorten b/c the load is too great
Term
concentric vs. eccentric contractions
Definition
Concentric: muscle fiber shortens when force is greater than the load

Eccentric: muscle may lengthen, despite contraction, if the load is too great (ripping, tearing, overextension of muscle)
Term
muscle strength determined by (4)
Definition
1. number of fibers recruited to contract
2. frequency of stimulation
3. thickness of each muscle fiber
4. initial length of the fiber at rest
Term
where do muscles get their energy? (3)
Definition
1. at rest/mild exercise: fatty acids
2. moderate exercise: gycogen stores
3. heavy exercise: blood glucose
Term
slow-twitch fibers
(type I)
Definition
1. type I
2. slower contraction speed
3. slow to fatigue
4. more mitochondria
5. also called SLOW OXIDATIVE FIBERS
Term
fast-twitch fibers
(type II)
Definition
1. faster contraction speed
2. fatigue fast
3. fewer mitochondria
4. also called WHITE FIBERS
Term
fast-twitch fibers
(type IIA)
Definition
1. fast-twitch, but with high oxidative capacity
2. also called FAST OXIDATIVE FIBERS
Term
why does muscle fatique happen? (5)
Definition
1. lactic acid build up
2. increased PO4 concentration
3. lack of ATP
4. build up of ADP
5. fatigue of upper motor neurons
Term
muscle repair
Definition
1. skeletal muscles have stem cells called satellite cells
- can fuse to damaged muscle cells and repair them or form new
- myostatin inhibits satellite cells
Term
lower motor neurons
Definition
1. alpha: contracting
2. gamma: stretching
3. coactivation (stimulated by upper neurons too)
Term
golgi tendon organs
Definition
1. monitor tension on tendons
Term
muscle spindle apparatus
Definition
1. respond to muscle length
2. muscles requiring more control have more spindles
3. when muscles stretch, spindles stretch
Term
cardiac and smooth muscle
Definition
1. involuntary
2. regulated by autonomic nervous system
3. contraction due to myosin/actin cross bridges stimulated by calcium, like skeletal muscles
Term
cardiac muscle (4)
Definition
1. striated
2. myosin and actin filaments from sarcomeres
3. contraction by sliding filaments
4. short, branched unlike skeletal muscles
Term
smooth muscle
Definition
1. in blood vessel walls, bronchioles, digestive organs, urinary and reproductive tracts
2. peristaltic waves
3. no sarcomeres
4. long actin filaments
5. some myosin filaments
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