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Chapter 2
Epistemology in Science
12
Chemistry
Undergraduate 4
09/07/2013

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Term
Describe the methodology of “strong inference”.
Definition
(1) Devise alternative hypotheses
(2) Devise an experiment, with alternative possible outcomes, each of which
will, as nearly as possible, exclude one or more of the hypotheses
(3) Carry out the experiment to get a clean result
(4) Go to (1)
Term
In what ways are models useful to science?
Definition

Models are useful to predict properties and behavior of phenomena being
studied.
 The predictions (and therefore the model) may be experimentally tested, in
which case the predictions would be “hypotheses”.

Term
What is the conclusion of the Meselson-Stahl experiment?
Definition
DNA replication is semi-conservative.
Term
What is the most salient feature of a model for DNA when one describes DNA replication
as “semi-conservative”?
Definition
DNA is double-stranded.
Term
epistemology
Definition
The theory of knowledge, especially with regard to its methods, validity,
and scope. Epistemology is the investigation of what distinguishes justified belief
from opinion.
Term
inference
Definition
A conclusion reached on the basis of evidence and reasoning.
· The process of reaching such a conclusion.
Term
strong inference
Definition
Elimination of hypotheses through evidence gathering.
Term
statistical inference
Definition
Calculating the probability that a given hypothesis is correct from
evidence.
Term
model-independent realism
Definition
The idea that a physical theory or world picture is a model
(generally mathematical in nature) and a set of rules that connect the model to
observations.
Term
DNA replication
Definition
The process of making a copy of a DNA molecule, resulting in two
identical DNA moleules.
Term
conservative DNA replication
Definition
A parent DNA molecule is completely intact before and
after DNA replication.
Term
semi-conservative DNA replication
Definition
The two strands of a parent DNA molecule are
split between the two replicate DNA molecules such that each replicate has one of
the parent strands.
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