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Chapter 11
Radiation Isodose Distribution
35
Physics
Graduate
05/01/2010

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Term
Horns are created by what?
Definition
Flattening filter which is designed to overcompensate near surface in order to obtain flat isodose curves at 10cm.
Term
Define Penumbra
Definition
Dose rate decreases rapidly as a function of lat distance from the CA.
Term
What is the falloff near the edge of the beam caused by?
Definition
Geometric penumbra and reduced side scatter
Term
Physical Penumbra consists of...?
Definition

Physical penumbra consists of:

-Geometric penumbra (due to finite source size)

-Transmission penumbra ( due to transmission through jaws)

-Scatter penumbra (due to in-phantom scatter)

Term
What does Physical Penumbra depend on?
Definition

Energy

Source size

SSD

Source to collimator distance

Depth in phantom

Term
Definition on Physical Penumbra?
Definition
the lateral distance between two specific isodose lines at a specified depth (eg lateral distance between 80 and 20% isodose lines at the depth of Dmax.)
Term
What do you measure Isodose curves with?
Definition

Most reliable- Ionization chambers because of flat energy response and precision

Solid state detectors (diodes), ideal for e- measurements

Film, not the easiest

Term
What is "Golden Data" and if using it what do you need to do?
Definition
It is preloaded isodose info from manufacturer. Must
-verify PDD data in a water phantom
-a deviation of 2% or less is acceptable up to a d=20cm.
Term
At higher energy, what is the attributes to the side scatter?
Definition
Collimators
Term
What has greatest effect on Iso curves,
-collimators
-flattening filter
-other absorbers?
Definition
Flattening filter. if no filter, conical field distribution.
Filter causes change in beam quality
Term
Flatness definition
Definition

The variation of dose relative to the CA over the ventral 80% of the f.s. at 10cm depth.

A variation of +/- 3% is acceptable.

Term
Symmetry definition
Definition

The variation of dose at any pair of points symmetrically situated with the CA ray.

It shouldn't differ by more that 2%.  

Term
What distance should be kept between wedge and skin?
Definition
15cm which will preserve the skin-sparing effect
Term
Wedge systems:
Individualized
Universal
Physical
Definition
Wedge systems: Individualized- a seperate wedge for each beam width to minimize the loss of beam output Universal-a single wedge for all beam widths, fixed centrally in the beam, always used in linacs Physical-Individual 15,30,45,60 (varian) and Universal, one 60degree mix open and wedge fields(elekta)
Term
Wedge Factor
Definition

Wedge factor= Dose with wedge/Dose without wedge

measured at a suitable depth beyond dmax (5 to 10cm)

Presence of wedge decreases the output and hardens the beam

Term
Physical wedges affect the beam how?
Definition

-Harden the beam

-Compton scattering which results in energy degradation (beam softening)

-Hardening also affects the DD distribution, wedged PDD should be measured

Term
POP advantages/disadvantages?
Definition

-Simple

-Less chance of a geometric miss

-Fairly homogeneous through the tumor

 

Disadvantages

-Excessive dose to normal tissue, often more than the tumor dose

Term
Tissue Lateral Effect
Definition
As the pt thinckness increases or the beam NRG decreases: -The central axis maximum dose near the surface increases relative to the midpoint dose
Term
WA/HA
Definition
WA= 90- HA/2
Term
GTV
Definition

ICRU 50

gross palpable or visible extent of tumor.

may consist of primary tumor, metastatic lymphadenopathy or other metastases. 

Term
CTV
Definition

ICRU 50

Clinical Target Volume

It contains the GTV and sub-clinical microscopic disease. Must be tx'd adequately for cure.

Term
Internal Margin (IM)
Definition

ICRU 62

added to the CTV to compensate for physiological movements and size, shape, and position of the CTV during therapy.

CTV+IM=ITV (internal target volume) commonly asymmetric around the CTV, accounts for movement, respiration, filling of bladder/rectum.

Term
Set-up margin (SM)
Definition

ICRU 62

accounts for uncertainties in pt positioning and alignment during tx planning and delivery.

Term
PTV
Definition

ICRU 50

 

PTV=CTV+IM+SM

Term
Treated Volume
Definition

ICRU 50

The volume enclosed by an isodose surface deemed appropriate to achieve tx goal.

Term
Irradiated Volume
Definition

ICRU 50

The tissue volume which receives a dose that is considered significant in relation to normal tissue tolerance. Depends on treatment technique used

Term
ICRU reference point
Definition

-Always at the center of the PTV

-and when possible, at the intersection of the beam axes

The dose at the ICRU reference point is the ICRU reference dose

-For single field: on CA at center of target

-for  POP equal weight: on CA, midplane.

-for POP unequal weight: at center of target

 

Term
Geometric Penumbra
Definition

Depends on Source size, distance from source, SDD.

exists both inside and outside of the geometric boundaries of the beam.

edge sharpness... also depends on reduced side scatter, so geometric penumbra isn't best to describe beam edge sharpness- use physical penumbra

Term
Rotational therapy dose rate
Definition

Diso= Dref x T

Dref= reference dose rate related to quantity T.

T is the avg TAR or TMR.

If using TMR, Diso=D0 x Sc x Sp x TMR

D0 is the Dmax for a 10x10 field at SAD

Term
Example of Rotational calc:


250 rad at iso
SAD=100
avg TMR=0.746, Sc=0.98, Sp=0.99
Machine output is 200MU/min
Definition

Diso=Do x Sc x Sp x avgTMR

=200 x 0.98 x 0.99 x 0.746= 144.8 rad/min

 

Tx time= 250 rad/144.8rad/min= 1.73min

 

Total MU to be set= 200MU/min x 1.73 min= 345MU

Term
Hot spot
Definition
An area outside the target volume that is hotter than the prescribed dose. Must be at least 2cm² to be clinically significant
Term
Mean target dose
Definition
the mean of the absorbed dose at a large number of points uniformly distributed in the target area
Term
Median Target Dose
Definition
value between the max and min absorbed dose values within the target.
Term
Modal Target dose
Definition
The absorbed dose that occurs most frequently within the target area.
Term
What is Integral Dose?
Definition
a measure of the total energy absorbed in the treated volume. If the volume receives a uniform dose, then it equals mass x dose. It is one way to compare dose distributions of different-quality beams. Its units are kg·Gy or joule (since 1Gy=1J/kg). Try to keep intregral dose to a minimum.
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