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Chapter 11 Cell Communication
Campbell Biology Chapter 11 Cell Communication
17
Biology
11th Grade
11/27/2011

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Term
signal transduction pathway
Definition
process by which a signal on a cell's surface is converted into a specific cellular response
Term
local regulator
Definition
substance that influences cells in the vicinity
Term
hormones
Definition
chemicals that are released into the circulatory system to travel to distant target cells
Term
ligand
Definition
small molecule that binds to a larger one, usually to a receptor on the cell surface
Term
G protein linked receptor
Definition
plasma membrane receptor that works with the help of a G protein
Term
G protein
Definition
loosely attached to the cytoplasmic side of the plasma membrane, functions as a switch. When GDP is bound=off. When GTP is bound = active
Term
tyrosine kinase
Definition
enzyme that catalyzes the transfer of phosphate groups from ATP to the amino acid tyrosine on a substrate protein
Term
tyrosine-kinase receptors
Definition
membrane receptors that attach phosphates to protein kinases
Term
ligand gated ion channels
Definition
protein pores in the plasma membrane that open or close in response to a chemical signal, thus allowing or blocking the flow of specific ions such as Ca+2 or Na+1
Term
protein kinase
Definition
enzyme that transfers phosphate groups from ATP to a protein
Term
protein phosphatase
Definition
enzymes that remove phosphate groups from proteins
Term
second messengers
Definition
small,nonprotein, water soluble molecules or ions (Ca+2 or cAMP)
Term
cyclic AMP (cAMP)
Definition
second messenger, involved in epinephrine breakdown of glucagon)
Term
adenylyl cyclase
Definition
enzyme built into the plasma membrane that converts ATP to cAMP in response to epinephrine binding to a receptor protein
Term
diacylglycerol (DAG)
Definition
second messenger, produced by the cleavage of phospholipid in plasma membrane
Term
inositol triphoshpate (IP3)
Definition
second messenger, produced by the cleavage of phospholipid in plasma membrane
Term
calmodulin
Definition
calcium ion binding protein present in high levels in eukaryotic cells; changes shape when calcium binds to it then binds to other proteins and activates or deactivates them
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