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Chapter 10
Lipids
18
Biochemistry
Undergraduate 3
03/21/2016

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Term
phospholipids
Definition
when a polar head group is joined to the hydrophobic moiety by a phosphodiester linkage in glycerophospholipids & some sphingolipids
Term
glycolipids
Definition
sphingolipids which lack phosphate but have a simple sugar or complex oligosaccharide at their polar ends
Term
glycerophospholipids
Definition
membrane lipids in which two fatty acids are attached in ester linkage to the first & second carbons of glycerol & a highly polar or charged group is attached through a phosphodiester linkage to the third carbon (AKA phosphoglycerides)
Term
ether lipids
Definition
can be found in some animal tissues & some unicellular organisms; one of the two acyl chains is attached to glycerol in ether (not ester) linkage
Term
plasmalogens
Definition
ether lipids which have an ether-linked chain that contains a double bond between C-1 & C-2 (rather than being saturated as in the alkyl ether lipids)
Term
platelet-activating factor
Definition
an ether lipid; acts as a potent molecular signal
Term
galactolipids
Definition
the type of membrane lipids that predominate in plant cells; one or two galactose residues are connected by a glycosidic linkage to C-3 of a 1,2-diacylglycerol
Term
sphingolipids
Definition
the class of membrane lipids which have a polar head group & two nonpolar tails but contain no glycerol (unlike glycerophospholipids & galactolipids)
Term
ceramide
Definition
the compound that results when a fatty acid is attached in amide linkage to the -NH2 on C-2; structurally similar to a diacylglycerol
Term
sphingomyelins
Definition
contain phosphocholine or phosphoethanolamine as their polar head group & are classified along with glycerophospholipids as phospholipids
Term
glycosphingolipids
Definition
occur largely in the outer face of plasma membranes & have head groups with one or more sugars connected directly to the -OH at C-1 of the ceramide moiety; do not contain phosphate
Term
cerebrosides
Definition
have a single sugar linked to ceramide; those with galactose are characteristically found in the plasma membranes of cells in neural tissue & those with glucose in the plasma membranes of cells in nonneural tissues
Term
globosides
Definition
glycosphingolipids with two or more sugars (usually D-glucose, D-galactose, or N-acetyl-D-galactosamine)
Term
neutral glycolipids
Definition
cerebrosides & globosides; they have no charge at pH 7
Term
gangliosides
Definition
the most complex sphingolipids that have oligosaccharides as their polar head groups & one or more residues of N-acetylneuraminic acid (a sialic acid) at the termini
Term
sterols
Definition
structural lipids present in the membranes of most eukaryotic cells
Term
cholesterol
Definition
the major sterol in animal tissues that is amphipathic (a polar head group & a non-polar hydrocarbon body about as long as a 16-carbon fatty acid in its extended form)
Term
bile acids
Definition
polar derivatives of cholesterol that act as detergents in the intestine by emulsifying dietary fats to make them more readily accessible to digestive lipases
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