Term
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Definition
| Chemicals that affect the physiology in any manner |
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Term
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Definition
| drugs used to treat diseases |
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Term
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Definition
| chemically modified antibiotics |
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Term
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Definition
| completely synthesized in the lab |
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Term
| Antibiotics are produced by what microorganisms? |
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Definition
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Term
| Who invented the cure for syphilis and when? |
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Definition
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Term
| What is the treatment for syphilis? |
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Definition
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Term
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Definition
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Term
| What mold (fungi) does penicillin come from? |
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Definition
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Term
| What bacteria causes syphilis? |
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Definition
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Term
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Definition
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Term
| What kind of antibiotic is prontosil? |
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Definition
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Term
| Who invented tetracycline? |
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Definition
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Term
| What are the two generas that fungi microorganisms produce into an antimicrobial agent? |
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Definition
| Penicillium and cephalosporium |
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Term
| What are the four generas of microorganisms that produce antimicrobials from bacteria? |
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Definition
| Bacillus, streptomyces, micromonospora, and pseudomonoas |
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Term
| What antimicrobial drug is described: Antimicrobial drug that inhibits protein synthesis in bacteria by blocking the initiation of translation and causes the misreading of mRNA? |
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Definition
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Term
| What antimicrobial drug is described: inhibits protein synthesis in bacteria by blocking the attachment of tRNA to the ribosome. |
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Definition
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Term
| What antimicrobial drug is described: inhibits protein synthesis in bacteria by preventing peptide bonds from being formed? |
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Definition
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Term
| What antimicrobial drugs are described: inhibits protein synthesis by preventing the continuation of protein synthesis. |
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Definition
| macrolides and lincosamides |
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Term
| Which antimicrobial drug is described: inhibit protein synthesis by interfering with a distinct step of protein synthesis. |
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Definition
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Term
| Which antimicrobial drug is described: inhibit protein synthesis in bacteria by interfering with the initiation of protein synthesis |
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Definition
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Term
| Which two antimicrobial drugs affect the 30S subunit of ribosomes? |
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Definition
| Aminoglycosides/Tetracyclines |
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Term
| Macrolides, Chloramphenicol, lincosamides, oxazolidinones, and streptogramins affect which subunit of the ribosome? |
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Definition
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Term
| What part of the ribosome contains the enzymatic portion that forms peptide bonds? |
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Definition
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Term
| What parts of the ribsome play a role in the initiation of protein synthesis? |
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Definition
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Term
| Humans or eukaryotes have what type of ribosomes and are composed of what subunits? |
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Definition
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Term
| What are two examples of antimicrobials that affect metabolism (antimetabolise)? |
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Definition
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Term
| If a microbial affects metabolism it is going to affect _______. |
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Definition
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Term
| Antimicrobial drugs that affect metabolism block what pathway? |
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Definition
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Term
| In bacteria, folate does what? |
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Definition
| synthesize nucleotides for DNA & RNA |
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Term
| Sulfonamides are effective they are _______ to _______ which is crucial in the synthesis of nucleotides required for DNA and RNA synthesis. |
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Definition
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Term
| sulfonamides bind to the enzyme that converts PABA into what? They compete to bind and this decreases production and then causes death |
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Definition
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Term
| The antimicrobial that binds to the enzyme involved in the conversion of dihydrofolic acid to THF. |
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Definition
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Term
| Cells use ribosomes to translate proteins using information from ______ templates. |
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Definition
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Term
| Both 30s and 50s play a role in the initiation of protein synthesis, condon recognition, and in the docking of tRNA. Which one contains the enzymatic portion that actually forms the peptide bonds? |
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Definition
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Term
| What antimicrobial drugs change the shape of the 30s subunit preventing the ribosome to read condons of mRNA and block the tRNA docking site preventing growth of polypeptide? |
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Definition
| Aminoglycosides and tetracyclines |
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Term
| These drugs: Chloramphenicol, lincosamides, and macrolides deal with which subunit of ribosome? |
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Definition
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Term
| Which drug block the enzymatic site of 50s subunit which prevents translation? |
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Definition
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Term
| What antimicrobials bind to a different portion of the 50s preventing movement of the ribosome from one codon to the next. Translation is frozen and protein synthesis is halted? |
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Definition
| Macrolides and Lincosamides |
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Term
| What antimicrobial inhibits protein synthesis by stopping protein synthesis by blocking initiation of translation. |
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Definition
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Term
These antimicrobials do what?
Aminoglycosides (streptomycin/gentamicin)
Tetracyclines
chloramphenicol
macrolides
lincosamides
(erythromycin/streptograms)
oxazolidinones |
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Definition
| inhibit protein synthesis |
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Term
These antimicrobials do what?
Sulfonamides
Trimethoprim |
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Definition
| Inhibition of metabolic pathway |
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Term
| __________ drugs are antimetabolic that kill bacteria by inhibiting nucleic acid synthesis. |
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Definition
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Term
| Polyenes, Azoles, Allyamines,Griseofulvin and Flucytosine are what kind of drugs? |
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Definition
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Term
| Which antifungal drugs action is to disrupt the plasma/cytoplasmic membrane? |
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Definition
| polyenes, azoles, allyamines |
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Term
| This type of drug kills fungi because it attaches to ergosterol and in the process distrupts the cell membrane and causes lysis of the cell |
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Definition
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Term
| This type of drug acts by inhibiting the synthesis of ergosterol. |
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Definition
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Term
| terbinafine is what kind of antifungal? |
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Definition
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Term
| What is the antimicrobial that works against bacteria and disrupts the cytoplasmic/plasma membrane? |
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Definition
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Term
| What antifungal deactivates tubulin, preventing cytokinesis and segregation of chromosomes during mitosis? |
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Definition
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Term
| To get rid of ring worm you should use which antifungal? |
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Definition
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