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| Exaggerated, life-threatening hypersensitivity reaction to a previously encountered antigen |
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| Protective protein produced by B lymphocytes in response to the presence of a foreign substance called an antigen, which the immune system regards as harmful to the host |
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| Substance that is recognized as harmful to the host and stimulates the formation of antibodies in an immunocompetent individual |
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| Acquired specific resistance, mediated by T cells, that produces reactive subsances or directly exerts a cytotoxic effect on a cell that is identified as harmful |
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| Organism in or on which another, usually parasitic, organisim is nourish and harbored |
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| Acquired specific resistance,mediated by B cells, that produces antibodies that bind to and dispose of antigens |
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| Able to develop an immune response; able to recognize antigens and respond to them |
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| Study of disease states associated with over-reactivity or under-reactivity of the immune response |
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| Infection occurring in a person with a weakened immune system and caused by microorganism that under normal conditions, would not bring about disease |
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| Treatment that provides relief, but not a cure |
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| Liquid portion of blood that remains after the removal of fibrinogen |
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| Neutrophils; Eosinophils; Basophils |
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| most numerous circulating leukocyte - protective action: phagocytosis; first cell to appear @ the site of injury or infection |
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| Begins the allergic reation - releases Histamines & Heparin |
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| End allergic reactions & parasites by releasing substances that neutralize toxic compounds |
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| abnormal condition; increase (used primarily with blood cells) |
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| other; differing from the normal |
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- Associated with bone marrow failure - Diminished numbers of white blood cells and platelets due to bone marrow suppression - Serious form of anemia that may be fatal |
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| Folic-Acid deficiency anemia |
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| Normal levels achieved by increasing folic acid in the diet or eliminating contributing causes |
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- Associated with premature destruction of red blood cells - Usually accompanied by jaundice |
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- Associated with loss of blood volume - Normal levels achieved with correction of underlying disorder |
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| Most common type of anemia worldwide |
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- Chronic, progressive disorder found mostly in people older than age 50 - Treated with B12 injections |
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- Most common genetic disorder in people of African descent - Characterized by red blood cells that change from their normal shape to crescents and other irregular shapes that cannot enter capillaries when oxygen levels are low, resulting in severe pain and internal bleeding - Manifests only in patients with both genes for the trait, not those with only one gene for the trait, who are merely carriers of the disease |
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| Condition of marked variation in the size of erythrocytes, when observed on a blood smear |
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| Accumulation of serous fluid in the peritoneal or pleural cavity |
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| Prescence of viable bacteria circulating in the bloodstream, and considered as "travelers" rather than a blood infection |
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| Recipient's immune system attacks a transplanted organ or tissue resulting in its destruction |
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| graft-versus-host reaction (GVHR) |
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| Condition that occurs following bone marrow transplants where the immune cells in the transplanted marrow produce antibodies against the host's tissues |
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| Localized accumulation of blood, usually clotted, in an organ, space, or tissue due to a break in or severing a blood vessel |
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| Any disorder caused by abnormalites in the hemoglobin molecule |
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| Destruction of RBCs with a release of hemoglobin that diffuses into the surrounding fluid |
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| Arrest of bleeding or circulation |
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| Immunity developed as a consequence of exposure to an antigen and the subsequent development of antibodies |
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| Immunity in which antibodies or other immune substances formed in one individual are transferred to another individual to provide immediate, temporary immunity |
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| Any disease of the lymph nodes |
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| Malignant neoplastic disorder of lymphatic tissue (not related to Hodgkin disease) |
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| Systemic disease associated with the presence and persistence of pathogenic microorganisms or their toxins in the blood; also called "blood infection" |
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| Blood test to detect the presence of antibodies, antigens or immune substances |
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| Blood test that measures the amount of antibodies in blood;commonly used as an indicator of immune status |
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| activated partial thromboplastin time (APTT) |
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| Test that screens for deficiencies of some clotting factors, valuable for preoperative screening for bleeding tendencies |
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| Test to determine the presence of pathogens in the bloodstream |
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| complete blood count (CBC) |
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| Series of tests that includes hemoglobin; hematocrit; red blood cell (RBC); white blood cell (WBC); platelet counts; differential WBC count; RBC indices; and RBC & WBC morphology |
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| Test tht enumerates the distribution of WBCs in a stained blood smear counting the different kinds of WBCs and reporting each as a percentage of the total examined |
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| erythrocyte sedimentation rate (ESR; sed rate) |
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| Measurement of the distance RBCs settle in 1 hour when whole blood is placed in a narrow tube |
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| Measurement of the amount of hemoglobin found in a whole blood sample |
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| measurement of the percentage of packed RBCs in a whole blood sameple; also called "crit" |
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| Serological test performed on a blood sample to detect the presence of a nonspecific antibody called the Heterophile antibody that is present in the serum of patients with infectious mononucleosis |
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| Test used to evaluate portions of the coagulation system and indirectly measure prothrobin; also called "pro time" |
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| Mathamatical calculation of the size, volume, and concentration of hemoglobin for a average red blood cell |
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| Test used to assess the absorption of radioactive vitamin B12 by the GI system |
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| Radiographic examination of lymph nodes after injection of a contrast medium |
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| Radiographic examination of lymph nodes or tissues after injection of contrast medium in lymph vessels |
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| Draw in or out using suction |
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| Procedure using a syringe with a thin aspirating needle that is inserted (usually in the sterum or pelvic bone) to withdraw a small sample of bone marrow fluid for microscopic evaluation |
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| Representative tissue sample removed from a body site for microscopic examination, usually to establish a diagosis |
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| Removal of a small core sample of tissue from bone marrow for examination under a microscope and, possibly, for analysis using other tests |
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| Removal of the first lymph node (also called the sentinel node) that receives drainage from cancer-containing areas and the one most likely to contain malignant cells |
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| Injecting of blood or blood components into the bloodstream |
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| Transfusion prepared from the recipient's own blood |
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| Transfusion prepared from another individual whose blood is compatible with that of the recipient |
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| Grafting of living tissue from its normal position to another site or from one person to another |
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| transplantation autologous bone marrow |
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| Harvesting, freezing (cryoperserving),and reinfusing the patient's own bone marrow; used to treat bone marrow hypoplasia following cancer therapy |
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| transplantation homologous bone marrow |
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| Transplantation of bone marrow from one individual to another; used for treating aplatic anemia and immunodeficiency disorders |
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Prevent blood clot formation by inhibiting one or more clotting factors
Generic/Trade Names: enoxaparin/Lovenox heparin/Hep-Lock, Hep-Lock U/P warfarin/Coumadin |
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Kill or damage rapidly metabolizing cells
Generic/Trade names: doxorubicin hydrochloride/ Adriamycin PFS, Adriamycin RDF, Rubex |
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| antiprotozoals, antibiotics, & sulfa drugs (to treat PCP) |
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Treat Pneumocystis carnii pneumonia (PCP)
Generic/Trade Names: trimetrexate glucuronate/Neutrexin trimethoprim, sulfamethoxazole/Bactrim, Septra pentamidine/NebuPent, Pentam-300 |
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| antivirals (to treat HIV-AIDS) |
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Prevent the replication of viruses withing host cells
Generic/Trade Names: nelfinavir/Viracept lamivudine & zidovudine/Combivir zidovudine/AZT; Retrovir |
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Prevents and treat disorders resulting from a lack of prothrombin, which is commonly caused by a vitamin K deficiency
Generic/Trade name: phytonadione/Vitamin K, Mephyton |
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Prvent or control bleeding
Generic/Trade Names: aminocaproic acid/Amicar |
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Dissolved blood clots by destroying the fibrin strands that make up the clot
Generic/Trade Names: alteplase/Activase, t-PA streptokinase/Streptase urokinase/Abbokinase, Abbokinase Open-Cath |
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| blood groups A, AB, B & O |
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| aquired immunodeficiency syndrome |
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| acute lymphocytic leukemia |
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| acute myelogenous leukemia |
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| activated partial thromboplastin time |
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| basophil (type of white blood cell) |
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| chronic lymphocytic leukemia |
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| chronic myelogenous leukemia |
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| differential count (white blood cells) |
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| eosinophil (type of white blood cell) |
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| erythrocyte sedimentation rate; sedimentation rate |
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| hemolytic disease of the newborn |
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| human immunodeficiency virus |
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| idiopathic thrombocytopenia purpura |
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| mean corpuscular hemoglobin; mean cell hemoglobin (average amount of hemoglobin per cell) |
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| mean cell hemoglobin concentration (average concentration of hemoglobin in a single red cell) |
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| mean cell volume (average volume or size of a single red blood cell; high MCV = macrocytic cells; low MCV = microsytic cells) |
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| posteroanterior; pernicious anemia |
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| polymorphonuclear leukocyte |
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| prothrombin time, physical therapy |
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| partial thromboplastin time |
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| red blood cell, red blood count |
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| systemic lupus erythematosus |
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| white blood cell, white blood count |
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