Term
| Skeleton stores (4) minerals: |
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Definition
1. Calcium
2. Phosphate
3. Carbonate
4. Magnesium |
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Term
| What secretes ground substance |
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Definition
|
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Term
| ground substance is made up of what 2 thins? |
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Definition
1. proteoglycans
2. Hyaluronic Acid |
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Term
| Bone matrix is laid by what? |
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Definition
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Term
|
Definition
1. ground substance
2. collagen
3. other proteins |
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Term
| Osteoblasts are derived from what type of cells? |
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Definition
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Term
| osteoblasts produce ___________ |
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Definition
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Term
| Osteoblasts respond to which hormone? |
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Definition
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Term
| Osteoblasts produce which protein with an affinity for mineral constituents? |
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Definition
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Term
| What type of cells synthesize osteoid? |
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Definition
|
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Term
|
Definition
| non-mineralized bone matrix |
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Term
| Which type of cell mineralizes bone matrix? |
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Definition
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Term
| What stimulates osteoblasts in addition to PTH? |
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Definition
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Term
| osteoblasts use intercellular calcium signaling to include ___________ activity. |
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Definition
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Term
| Cytokine receptor activator nuclear factor kapp-B ligand |
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Definition
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Term
| What is expressed on OSTEOBLASTS and is necessary for forming osteoclasts? |
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Definition
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Term
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Definition
| bone is shaped according to its function |
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Term
| _____________ can be stimulated by colony stimulating factor and interleukins 1,3,6 |
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Definition
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Term
| Osteoblasts are affected by _________ _________ |
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Definition
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Term
| Osteoblasts loosen their grip on the bone surface under the effect of _______________ |
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Definition
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Term
| Once resorption is complete, osteoclasts disappear and either _____________ or revert back to _________ ________ or ____________. |
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Definition
1. degenerate
2. revert back to parent cell
3. move away from the scene. |
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Term
| Calcitonin is produced in the ... |
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Definition
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Term
| Osteoclasts are thought to form from _____________ |
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Definition
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Term
| Osteoclasts are thought to form from _____________ |
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Definition
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Term
| Osteoclasts attach to bone through |
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Definition
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Term
| Large, multinucleated cells |
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Definition
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Term
| osteoclasts resorb bone through _______ and _______ __________ |
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Definition
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Term
| osteoclasts contain lysosomes filled with |
|
Definition
Hydrolytic enzymes...
used to degrade bone. |
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Term
| Proteinases produced by osteoclasts help digest _____________ |
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Definition
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Term
| Osteoblasts surrounded in lacunae by osteoid as it hardens secondary to deposited minerals = |
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Definition
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Term
| synthesize matrix molecules for bone calcification |
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Definition
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Term
| ____________ work as mechanosensors in bone |
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Definition
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Term
| once bone around osteoblasts becomes minerals they are called |
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Definition
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Term
| ___________ obtain nutrients from capillaries in the canaliculae |
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Definition
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Term
| ____________ aid in modifying bone matrix through release of enzymes to dissolve minearalized walls of lacuna to prepare bone for remodeling |
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Definition
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Term
made up of extracellular elements of bone:
collagen, ground substances, minerals, proteins... |
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Definition
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Term
| where mineralization takes place |
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Definition
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Term
| collagen molecules assemble in 3 tiny chains to form: |
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Definition
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Term
| fibrils make a staggered pattern that will be the space for ____________ |
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Definition
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Term
| strengthen bone and assist bone calcium deposition |
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Definition
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Term
| control collagen interactions that lead to fibril formation |
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Definition
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Term
| bone mineralization (2 minerals) |
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Definition
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Term
| In addition to collagen fibers in the bone, the components of the bone matrix include (3)... |
|
Definition
1. proteoglycans
2. glycoproteins
3. calcium and phosphate minerals. |
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Term
|
Definition
| majority of minerals in the body |
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Term
|
Definition
| made up of calcium and phosphorous |
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Term
| haversian systems are located in _________ bone |
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Definition
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Term
| Haversian systems include (5) things: |
|
Definition
1. haversian canal
2. lamellae
3. lacunae
4. osteocyte
5. canaliculi |
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Term
| Instead of haversian systems, spongy (cancellous) bone has: |
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Definition
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Term
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Definition
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Term
|
Definition
| concentric layers of bone matrix around haversian canal |
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Term
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Definition
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Term
|
Definition
| concentric layers of bone matrix around haversian canal |
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Term
|
Definition
| tiny spaces btwn lamella with osteocytes inside |
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Term
| outer layer of bone. Contains blood vessels and nerves |
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Definition
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Term
| cancellous bone is located inside of compact bone inside of the ___________ portion of the long bone. |
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Definition
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Term
| red marrow is in which type of bone |
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Definition
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|
Term
yellow marrow is inside:
it is made up of: |
|
Definition
diaphysis of cortical bone
fat |
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|
Term
| canals that help with comuncation and secretion for repair process. they are between osteocytes. Blood vessels run through them |
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Definition
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Term
| haversian canals are joined horizontally by : |
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Definition
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Term
| Does yellow marrow ever help red marrow in hematopoiesis? |
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Definition
| yes, but only in times of stress |
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Term
| In children, the epiphysis and metaphysis are separated by ___________ |
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Definition
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Term
| the bone that sits on the back of your kene behind the patella = |
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Definition
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