Term
| Penicillins-how do they work |
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Definition
| inhibit enzymes involved in cross-linking of the peptidoglycan chain (transpeptidation reactions), activate a cell's own cell wall lytic enzymes. |
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Term
| penicillins-who/what do they kill |
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Definition
penicillin G, V and methicilin: narrow spectrum, gram positive
Ampicillin, Carbenicillin: broad spectrum, G+ and some G- |
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Term
| Cephalosporins-what do they do |
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Definition
| is similar to penicillin in structure so it does the same thing, prevent peptidoglycan cross linkages |
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Term
| cephalosporins-who do they kill |
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Definition
| broad spectrum: G+ and some G- |
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Term
| penicillin side effects and interesting crap |
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Definition
-least toxic of antibiotics, but 1-5% of US adults are allergic, some die of violent reactions
-comes from a fungus |
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Term
| side effects of cephalosporins |
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Definition
| allergies, renal damage, thrombophebitis |
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Term
| vancomycin-how it kills bacterias |
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Definition
| prevents transpeptidation of peptidoglycan (no cross linkages) but is different from penicillin b/c it binds to the D-Alanine-D-alanine terminal part |
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Term
| vancomycoin who does it kill? |
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Definition
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Term
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Definition
| tinnitis, deafness, kidney damage (nephrotoxcicity), allergies |
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Term
| which drugs inhibit cell wall synthesis? |
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Definition
penecillins
vancomycins
cephalosporins |
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