Shared Flashcard Set

Details

Cells: The Living Unit (ch.3)
cells
32
Physiology
Undergraduate 1
09/18/2010

Additional Physiology Flashcards

 


 

Cards

Term

What is the cell theory?

Definition

states that all organisms are made of cells and that all cells come from other cells

Term

What are the 2 main compartments of the cell?

Definition

cytoplasmic compartment and nuclear compartment

Term

Describe the structure, components, functions and characteristics of the plasma membrane

Definition

a. is a barrier,boundary, of a cell

b. is selctive and semipermeable

    i.  hydrophobic core is selective against particles that arelarge/charged

       and do not allow them to cross in/out of cell without the help

       of a carrier/channel

c. is a bilayer of phospholipids-2 hydrophilic surfaces(heads) and 2 hydrophobic cores(hydrocarbon tails)

d. composed of :

phospholipids-have a phosphoric hydrophilic head and 2 hydrocarbon tails. cholesterol- lipid that helps form rafts in the membrane and control amt of space between phospholipids and thus how much the phospholipids components can drift

proteins-

glycocalyx- sugar coating of the surface of the cell; used as signaling molecules

 

Term

What are the functions of the proteins in the plasma membrane?

Definition

1. channels allow charged/large particles to pass through the membrane

2.carriers change shape to transport particles across the membrane

3.signaling molecules- for communication with other cells

4.receptors- for binding and signaling molecules

5.cellular junctions- connect neighboring cells

6. enzymes- catalyze reactions on the internal/external surface of the cell

7.recognition- for the immune system to recognize the cell as "self"

Term

What is the fluid-mosaic theory?

Definition

fluid=able to move

mosaic= made of many things

the membrane is made of many things and those parts are able to change their position along the membrane

Term
What is a specificity receptor?
Definition
receptors have specific shapes and can only bind substances that fit their shape
Term
What does eukaryotic mean?
Definition
has a true nucleus- the DNA is kept within an organelle called a nucleus, so it is not in the same compartment as the ctoplasmic components
Term
What is a competition receptor?
Definition
a receptor can only bind one substance at a given time. If mroe than one substance have the shape that fits the receptor, they compete for the binding site
Term
What is saturation?
Definition

"to fully occupy"

if all the recpetors present are currently full, they are saturated

Term
What is transport maximum?
Definition
the amount of substance that can occupy all of the present receptors is the transport max.(the amt. of substance that can be transported at a given time
Term
What are autocrines?
Definition
molecules released by a cell that will bind to receptors on that same cell to signal that cell to do something
Term
What are paracrines?
Definition
molecules that are released by a cell and will bind to receptors on that cell's neighbors(close by) to change their function
Term
What are hormones?
Definition
molecules released by cells that will enter the blood stream to travel to distant cells(target cells) and bind to their receptors to alter their function
Term
What are neurotransmitters?
Definition
molecules released by a neuron that will bind to another neuron or a cell of an effector organ to cause a response
Term
List and describe the different modes of action of membrane proteins(receptors)
Definition

ligand receptor-when the ligand binds to the receptor, the gate opens

G-protein receptors- attached to receptor protein.When a signal binds to the receptor the G protein is released and shifts in the membrane to activate another component in the membrane(such as an enzyme or channel)

enzyme receptors- some enzymes in the plasma membrane have receptors and are tuned on/off by a signal molecule. The is one way for the body to control when substrate is made by the enzyme

integrin receptors- attached to the cytoskeleton of the cell. When a signal molecule binds it triggers a change in the cytoskeleton

 

Term
List and describe the 3 cell junctions
Definition

tight junction-"button" type proteins between cells that "seal the gap" so that particles cannot pass between cells

desmosomes-"anchoring" protiens that hold neighboring cells tightly together. Important for cells that are under pressure(heart)

gap junctions-"tunnel" like protiens that allow molecules to pass directly from the inside of one cell to the inside of the neighboring cell

Term
What is glycocalyx? What is MHC and why is it important?
Definition
It is the sugar coating on the surface of cell. Various sugars can be found on the protiens and lipids of the cell membrane and serve as cell signaling molecules
Term
What is membrane transport?
Definition
The act of bringing a particle across a membrane. can be accomplished by: channels, carries or vesicles
Term
What is diffusion?
Definition
the movement of particles through space (across a membrane)
Term
What are the 3 types of diffusion?
Definition

simple diffusion- no energy or channel is needed. Particle can diffuse across the membrane of its own accord without help.(very small particles with no charge)

 

facilitative diffusion-a channel or carrier is needed for the partivle to cross the membrane, but energy does not need to be applied

 

active diffusion- both a carrier and energy are needed to transport the particle across the membrane

Term
Describe concentration gradient?
Definition
the concentration of the substance changes from one area of space to the next
Term
What is osmosis?
Definition
it is specifically the diffusion of water across a membrane. Water will diffuse across a membrane to dilute a substance until the concentration of that substance is equal on either side of the membrane
Term
Describe the tonicity of a solution campared to a cell in the body
Definition

hypotonic- concentration of solute in the solution is LESS than the concentration of solution inside a cell. This will cause water to flow into the cell to dilute the solute

 

hypertonic-concentration of solute in the solution is GREATER than the concentration of solute inside the cell. This will cause water to move out of the cell to dilute the solute

 

isotonic-the concentration of solute is equal in solution and in the cell. Water still moves. Just has no NET movement- for every one that goes into the cell, one will come out and vice versa

Term
Describe primary and secondary active transport. What is the difference between the two?
Definition

both use energy and a carrier to transport a substance across a membrane against its concentration gradient. 

primary-a substance loads into a carrier. Energy from binding a phosphate from ATP to the carrier is used to change the carrier's position and then the substance is released to the other side of the membrane.  The bond from the phosphate can be broken to once again provide energy to the carrier to face it to the original position(can bring another molecule with it).

 

secondary- a carrier uses energy from the bonding phosphate  from ATP to transport a molecule actoss the membrane against its conc. grad. to make it so that the molecule is available bind to another carrier loaded with a second substance and cause that carrier to change position and transport them across the membrane. So the 2nd substanceis transported at the esspense of the energy used to move the first across the membrane.

Term
What is vesicular transport? What do cells use it for? List and describe the 2 types of vesicular transport
Definition

vesicular transport- moving a substance into/out of/within the cell with the use of a vesicle.

 

cells use it for moving substances from one place to the next within the cell (such as from rough ER to Golgi), or for taking substances into the cytoplasm or out into the ECF.

 

2 main types are endocytosis (taking in) and exocytosis (releasing out).

endocytosis- the plasma membrane envelops the substance outside the cell and pinches off from the membrane and now you have a vesicle in the cytoplasm with substance in it. PINOCYTOSIS= endocytosis of fluids, PHAGOCYTOSIS= endocytosis of a solid

exocytosis- vesicle within the cell docks with the plasma membrane and releases the substance to the ECF.

Term
List and describe the components of the endomembrane system
Definition

a.rough ER-used for protein synthesis. It's continuous with the membrane of the nucleusat its pores

 

b.smooth ER- used for lipid synthesis and detoxification of some substances

 

c.golgi apparatus- receives vesicles containing the protein made by the rough ER. Will modify these proteins by adding sugars to them if needed, then put them back into vesicles to be transported to another area of the cell, or to the plasme membrane for exocytosis

 

d.lysosomes- contain acids or substances like peroxides to break down cellular debris or substances that were endocytosed and need to be destroyed

Term
What is transepithelial movement? What are some examples?
Definition

this is when a cell takes in substances via channels or carriers in its membranes, then releases them from the other end of the cell. Can be facilitative, simple, or active processes.

 

ex:cells in the mucosa of the gut-nutrient molecules are taken in the apical surface facing the lumen, then released from the other side of the cell toward the blood supply

Term
What is membrane potential?
Definition
a value assigned to the amount of electric energy associated with the membrane due to different ion concentrations, and therefore change, then released from the other side of the membrane
Term
List and describe the three components to the cytoskeleton
Definition

a.microtubles- tubulin protein that can form chains. Used for intracellular movements (they are used to move chromosomes during mitosis)

 

b.microfilaments- include actin and are used to constrict or contract a cell, such as the pinching motion when a cell divides

 

c.intermediate filaments- these provide structural support of a cell internally, like support beams of a building

Term
Describe cilia. What is its structure and its function?
Definition
apical modifications that are made of microtubles units(9+2 formation). They function in movement of substance across a lining, such as an edd along the fallopian tube.
Term
What is mitochondria? What process does it perform? What is the important product of that process?
Definition
membrane bound organelles that perform Kreb's and ETC of cellular respiration. The end product is ATP, water and HEAT
Term
What is adenosine triphosphate? How is it made? What is it used for?
Definition
ATP, the body's primary energy molecule. It is formed from what we eat. Three phosphates are added to an adenosine molecule. This can be recycled and is usually represented as ADP+Pi = ATP
Supporting users have an ad free experience!